Detailed information NTG0476990

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: H7797_RS05405
• Genome accession: NZ_CP060639
• Coordinates: 1073213..1074523 (-)
• Length: 436 a.a.
• NCBI ID: WP_085634321.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY153
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 1068213..1079523

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7797_RS05380 (H7797_05355)	-	1068818..1069870 (-)	1053	WP_002989701.1	BMP family protein	-
H7797_RS05385 (H7797_05360)	-	1069964..1070353 (-)	390	WP_011285547.1	cytidine deaminase	-
H7797_RS05390 (H7797_05365)	-	1071006..1071599 (-)	594	WP_010922352.1	class I SAM-dependent methyltransferase	-
H7797_RS05395 (H7797_05370)	coaA	1071867..1072787 (+)	921	WP_014407609.1	type I pantothenate kinase	-
H7797_RS05400 (H7797_05375)	rpsT	1072841..1073089 (+)	249	WP_009881183.1	30S ribosomal protein S20	-
H7797_RS05405 (H7797_05380)	ciaH	1073213..1074523 (-)	1311	WP_085634321.1	sensor histidine kinase	Regulator
H7797_RS05410 (H7797_05385)	ciaR	1074516..1075190 (-)	675	WP_002984519.1	response regulator transcription factor	Regulator
H7797_RS05415 (H7797_05390)	-	1075537..1078074 (-)	2538	WP_014407610.1	M1 family metallopeptidase	-
H7797_RS05420 (H7797_05395)	phoU	1078279..1078932 (-)	654	WP_002984514.1	phosphate signaling complex protein PhoU	-

Sequence

Protein

• Length: 436 a.a.
• Molecular weight: 50084.61 Da
• Isoelectric Point: 9.2692

>NTDB_id=476990 H7797_RS05405 WP_085634321.1 1073213..1074523(-) (ciaH) [Streptococcus pyogenes strain TSPY153]
MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYSSVDSSLVSVSNNASSYANRTMARISSFYFDTENNII
KALPDSDSSKLLGTPAANTDIILFSANGTILNAFDAFSNYQNFHLDKRRLGSIETTSLMNFYGQEEKYHTITVRVHIKNY
PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQN
QVNRSLRMDKALLKQLITILFDNAIKYTDKNGIIEIIAKTTDKNLLISVIDNGPGITDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVMSLKGNITVKDNDPKGSIFEVKL

Nucleotide

• Length: 1311 bp

>NTDB_id=476990 H7797_RS05405 WP_085634321.1 1073213..1074523(-) (ciaH) [Streptococcus pyogenes strain TSPY153]
ATGAATAAATTAAAAAAAGAGATTTTATCAGATAACTATAACCACTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTCATTATGACTATTATTATCTTACAGATTATGCGGTTTGGCGTTTATTCGTCAGTTGACAGTAGTTTAGTTTCTGTTA
GTAATAATGCAAGTAGCTATGCTAATCGTACGATGGCTAGAATATCTTCTTTTTACTTTGATACTGAAAATAACATTATT
AAGGCGCTGCCTGATTCAGATAGTTCTAAGTTATTAGGAACGCCTGCAGCTAATACAGATATCATTTTGTTTAGTGCTAA
TGGAACAATTTTAAATGCTTTTGATGCGTTTTCTAACTATCAAAATTTTCATTTAGATAAACGCCGGTTGGGGAGTATTG
AAACCACCAGTTTAATGAATTTTTATGGACAAGAAGAAAAATACCATACGATAACTGTAAGGGTTCATATCAAAAATTAT
CCTGCAGTTGCCTATATGATGGCAGTAGTAAATGTGGAACAATTAGACCGCGCTAATGAACGTTACGAGCGCATTATTAT
TATAGTTATGAGTGTTTTTTGGCTAATTTCTATTTTAGCAAGTATTTATTTAGCCAAGTGGAGCAGAAAACCTATTTTAG
AAAGCTATGAAAAACAAAAAATGTTTGTTGAAAATGCTAGTCATGAACTAAGGACCCCTTTGGCGGTCTTACAGAATCGT
CTGGAATCGCTTTTTCGTAAGCCCAACGAAACGATATTAGAAAATAGTGAGCATCTCGCTTCTAGTTTAGACGAGGTTCG
CAACATGCGCATCTTAACAACTAATTTATTAAATTTAGCAAGACGAGATGATGGCATTAATCCACAGTGGACTCATTTAG
ATACAGATTTTTTTAATGCTATTTTTGAGAATTATGAACTAGTTGCTAAAGAATATGGAAAAATATTTTATTTTCAGAAC
CAAGTCAATAGATCGTTAAGAATGGATAAGGCTTTACTAAAACAATTAATAACGATTTTATTTGACAATGCTATTAAATA
TACAGATAAAAATGGTATTATTGAAATTATAGCGAAAACAACGGACAAAAATTTATTAATTTCTGTTATTGATAATGGTC
CAGGGATAACAGATGAAGAAAAGAAAAAGATTTTTGATCGTTTTTATCGAGTTGACAAAGCTAGAACACGGCAAACAGGT
GGATTTGGCTTGGGGTTGGCTTTAGCTCAGCAAATCGTGATGTCTTTAAAAGGAAATATTACAGTAAAGGATAATGATCC
TAAAGGTAGTATTTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (220-285)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (329-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	57.666	100	0.578
ciaH	Streptococcus pneumoniae Rx1	51.37	100	0.516
ciaH	Streptococcus pneumoniae D39	51.37	100	0.516
ciaH	Streptococcus pneumoniae R6	51.37	100	0.516
ciaH	Streptococcus pneumoniae TIGR4	51.37	100	0.516