Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ATM22_RS04460 Genome accession   NZ_CP060528
Coordinates   945530..946159 (+) Length   209 a.a.
NCBI ID   WP_002473914.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain LM087     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 940530..951159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ATM22_RS04430 (ATM22_04395) - 940635..941171 (+) 537 WP_002494124.1 hypothetical protein -
  ATM22_RS04435 (ATM22_04400) - 941322..942308 (-) 987 WP_002494125.1 aromatic acid exporter family protein -
  ATM22_RS04440 (ATM22_04405) map 942482..943237 (+) 756 WP_002494126.1 type I methionyl aminopeptidase -
  ATM22_RS04445 (ATM22_04410) - 943395..943781 (+) 387 WP_001830382.1 hypothetical protein -
  ATM22_RS04450 (ATM22_04415) liaF 943796..944497 (+) 702 WP_002473931.1 cell wall-active antibiotics response protein LiaF -
  ATM22_RS04455 (ATM22_04420) vraS 944494..945540 (+) 1047 WP_002494127.1 sensor histidine kinase Regulator
  ATM22_RS04460 (ATM22_04425) vraR 945530..946159 (+) 630 WP_002473914.1 two-component system response regulator VraR Regulator
  ATM22_RS04465 (ATM22_04430) - 946216..947394 (-) 1179 WP_001830411.1 YihY/virulence factor BrkB family protein -
  ATM22_RS04470 (ATM22_04435) - 947801..948085 (-) 285 WP_002473916.1 YtxH domain-containing protein -
  ATM22_RS04475 (ATM22_04440) - 948093..948557 (-) 465 WP_001830437.1 low molecular weight protein-tyrosine-phosphatase -
  ATM22_RS04480 (ATM22_04445) - 948698..948913 (+) 216 WP_002494128.1 DUF1128 domain-containing protein -
  ATM22_RS04485 (ATM22_04450) - 948915..950156 (+) 1242 WP_002494129.1 aminopeptidase -
  ATM22_RS04490 (ATM22_04455) - 950236..950766 (+) 531 WP_002447436.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23598.22 Da        Isoelectric Point: 4.7218

>NTDB_id=476598 ATM22_RS04460 WP_002473914.1 945530..946159(+) (vraR) [Staphylococcus epidermidis strain LM087]
MAIKVLFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKEAITKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPQIKVV
MLTSFIEDKEVYRALDSGVDSYILKTTSASDIADAVRKTYEGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=476598 ATM22_RS04460 WP_002473914.1 945530..946159(+) (vraR) [Staphylococcus epidermidis strain LM087]
GTGGCGATTAAAGTTTTATTTGTTGATGATCATGAAATGGTAAGAATCGGTATTTCAAGCTATCTTTCAACTCAAGAAGA
TATAGAAGTAGTAGGTGAGGGTGCTTCTGGTAAAGAGGCTATCACTAAAGCGCATGAGCTAAAACCAGATTTAATATTAA
TGGATTTACTTATGGACGATATGGATGGTGTAGAAGCAACTACTGAAATTAAAAAAGATTTACCTCAAATTAAAGTAGTC
ATGTTAACAAGCTTTATAGAGGATAAAGAAGTTTATCGTGCACTTGATTCTGGAGTAGATAGTTATATTTTAAAGACAAC
AAGTGCAAGTGATATAGCTGACGCTGTGCGTAAAACGTATGAAGGTGAATCAGTATTTGAACCAGAAGTGTTAGTAAAAA
TGCGCAACCGTATGAAAAAACGTGCCGAGCTTTATGAAATGTTAACAGAAAGAGAAATGGAGATCCTATTACTTATAGCT
AAAGGATACTCTAACCAAGAGATTGCAAGCGCCTCTCATATCACCATCAAAACAGTAAAAACTCATGTAAGTAACATACT
GAGTAAATTAGAAGTTCAAGATCGAACACAAGCAGTAATCTATGCGTTCCAGCATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.215

100

0.952
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373