Detailed information NTG0476597

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ATM22_RS04455
• Genome accession: NZ_CP060528
• Coordinates: 944494..945540 (+)
• Length: 348 a.a.
• NCBI ID: WP_002494127.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain LM087
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 939494..950540

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ATM22_RS04430 (ATM22_04395)	-	940635..941171 (+)	537	WP_002494124.1	hypothetical protein	-
ATM22_RS04435 (ATM22_04400)	-	941322..942308 (-)	987	WP_002494125.1	aromatic acid exporter family protein	-
ATM22_RS04440 (ATM22_04405)	map	942482..943237 (+)	756	WP_002494126.1	type I methionyl aminopeptidase	-
ATM22_RS04445 (ATM22_04410)	-	943395..943781 (+)	387	WP_001830382.1	hypothetical protein	-
ATM22_RS04450 (ATM22_04415)	liaF	943796..944497 (+)	702	WP_002473931.1	cell wall-active antibiotics response protein LiaF	-
ATM22_RS04455 (ATM22_04420)	vraS	944494..945540 (+)	1047	WP_002494127.1	sensor histidine kinase	Regulator
ATM22_RS04460 (ATM22_04425)	vraR	945530..946159 (+)	630	WP_002473914.1	two-component system response regulator VraR	Regulator
ATM22_RS04465 (ATM22_04430)	-	946216..947394 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
ATM22_RS04470 (ATM22_04435)	-	947801..948085 (-)	285	WP_002473916.1	YtxH domain-containing protein	-
ATM22_RS04475 (ATM22_04440)	-	948093..948557 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
ATM22_RS04480 (ATM22_04445)	-	948698..948913 (+)	216	WP_002494128.1	DUF1128 domain-containing protein	-
ATM22_RS04485 (ATM22_04450)	-	948915..950156 (+)	1242	WP_002494129.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 39994.42 Da
• Isoelectric Point: 6.0544

>NTDB_id=476597 ATM22_RS04455 WP_002494127.1 944494..945540(+) (vraS) [Staphylococcus epidermidis strain LM087]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQGDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=476597 ATM22_RS04455 WP_002494127.1 944494..945540(+) (vraS) [Staphylococcus epidermidis strain LM087]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACGGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ACATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCAGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGGGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92