Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   JS609_RS06970 Genome accession   NZ_CP071043
Coordinates   1328681..1330030 (-) Length   449 a.a.
NCBI ID   WP_041333853.1    Uniprot ID   -
Organism   Bacillus subtilis isolate ELA2001105     
Function   degrading CSP; selective degradation of ComEA and ComEC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1323681..1335030
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JS609_RS06950 (JS609_01365) mhqA 1323864..1324814 (+) 951 WP_225721960.1 ring-cleaving dioxygenase -
  JS609_RS06955 - 1324923..1325018 (+) 96 Protein_1309 hypothetical protein -
  JS609_RS06960 (JS609_01366) ykcB 1325031..1327181 (+) 2151 WP_029317681.1 glycosyltransferase family 39 protein -
  JS609_RS06965 (JS609_01367) gtcC 1327193..1328164 (+) 972 WP_015715747.1 glycosyltransferase family 2 protein -
  JS609_RS06970 (JS609_01369) htrA 1328681..1330030 (-) 1350 WP_041333853.1 serine protease HtrA Regulator
  JS609_RS06975 (JS609_01370) proG 1330199..1331017 (+) 819 WP_088325706.1 pyrroline-5-carboxylate reductase ProG -
  JS609_RS06980 (JS609_01371) dppA 1331145..1331969 (+) 825 WP_014479576.1 D-aminopeptidase DppA -
  JS609_RS06985 (JS609_01372) dppB 1331986..1332912 (+) 927 WP_003245446.1 dipeptide ABC transporter permease DppB -
  JS609_RS06990 (JS609_01373) dppC 1332918..1333880 (+) 963 WP_225721961.1 dipeptide ABC transporter permease DppC -
  JS609_RS06995 (JS609_01374) dppD 1333885..1334892 (+) 1008 WP_029727040.1 dipeptide ABC transporter ATP-binding subunit DppD -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 47744.87 Da        Isoelectric Point: 4.5990

>NTDB_id=475807 JS609_RS06970 WP_041333853.1 1328681..1330030(-) (htrA) [Bacillus subtilis isolate ELA2001105]
MDNYRDENRTKGNENEVFLTKENDQSTSYSARNVIHDQEKKKRGFGWFRPLLGGVIGGSLALGIYTFTPLGDHDSQDTAK
QSSSQQQTQSVTATSTSSESKKSSSSSSAFKSEDSSKISDMVEDLSPAIVGITNLQAQSNSSLFGSSSSDSSEDTESGSG
SGVIFKKENGKAYIITNNHVVEGASSLKVSLYDGTEVTAKLVGSDSLTDLAVLQISDDHVTKVANFGDSSDLRTGETVIA
IGDPLGKDLSRTVTQGIVSGVDRTVSMSTSAGETSINVIQTDAAINPGNSGGPLLNTDGKIVGINSMKISEDDVEGIGFA
IPSNDVKPIAEELLSKGQIERPYIGVSMLDLEQVPQNYQEGTLGLFGSQLNKGVYIREVASGSPAEKAGLKAEDIIIGLK
GKEIDTGSELRNILYKDAKIGDTVEVKILRNGKEMTKKIKLDQKEEKTS

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=475807 JS609_RS06970 WP_041333853.1 1328681..1330030(-) (htrA) [Bacillus subtilis isolate ELA2001105]
ATGGATAACTATCGTGATGAAAACAGAACGAAAGGTAATGAGAATGAGGTCTTTTTAACGAAAGAGAACGATCAGAGCAC
CTCCTACTCGGCCCGCAATGTCATTCATGATCAGGAGAAGAAAAAACGAGGCTTCGGATGGTTCAGACCGTTGCTTGGCG
GAGTGATCGGCGGCAGTCTTGCCCTTGGCATTTACACGTTTACACCGCTTGGCGACCATGATTCTCAGGACACTGCAAAA
CAATCATCCAGCCAGCAGCAAACGCAATCTGTTACAGCAACAAGCACCTCCTCTGAATCTAAAAAAAGCTCAAGCAGCTC
ATCTGCATTCAAGAGCGAGGACTCTTCTAAAATCTCAGATATGGTAGAAGACCTTTCACCAGCGATTGTCGGTATTACAA
ATCTTCAGGCACAATCAAACAGCTCTTTGTTCGGCTCTAGTTCTTCTGATTCCAGCGAAGATACAGAAAGCGGTTCAGGG
TCAGGTGTCATTTTCAAAAAAGAGAATGGCAAGGCTTATATCATTACAAATAACCACGTCGTAGAAGGGGCATCATCACT
GAAGGTATCTTTATATGACGGCACTGAGGTTACTGCAAAGCTGGTAGGCAGTGACTCGTTAACTGATTTAGCCGTCCTCC
AAATCAGTGATGACCACGTCACAAAAGTGGCAAACTTCGGTGATTCATCTGATCTTAGAACAGGCGAGACCGTTATTGCG
ATTGGGGATCCGCTTGGAAAAGACCTGTCCCGCACAGTAACACAAGGAATTGTAAGCGGCGTGGACAGAACGGTTTCAAT
GTCTACATCAGCCGGCGAAACGAGCATTAACGTCATTCAGACAGACGCAGCAATTAATCCAGGTAACAGCGGCGGTCCTT
TGTTAAATACAGACGGCAAAATCGTCGGCATTAACAGTATGAAAATCAGTGAAGATGATGTTGAGGGTATCGGATTTGCC
ATTCCAAGCAATGACGTAAAACCGATTGCTGAAGAATTACTGTCTAAAGGACAAATTGAACGTCCATATATCGGTGTCAG
CATGCTTGATCTAGAACAAGTGCCGCAAAATTACCAAGAAGGCACACTCGGCCTGTTCGGCAGCCAGCTGAATAAAGGTG
TTTACATCCGTGAGGTCGCTTCAGGCTCTCCTGCTGAAAAGGCCGGATTAAAAGCGGAGGATATTATCATCGGCCTAAAA
GGTAAAGAAATTGATACAGGCAGTGAATTGCGCAATATCTTATATAAAGACGCAAAGATCGGTGATACCGTTGAAGTGAA
AATTCTCCGAAACGGCAAAGAAATGACGAAAAAAATTAAACTGGATCAAAAAGAAGAGAAAACTTCGTAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(342-441)

Trypsin-like peptidase domain (Trypsin_2)

(160-304)

Peptidase family M50 (Peptidase_M50)

(366-448)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus pneumoniae Rx1

41.045

89.532

0.367
  htrA Streptococcus pneumoniae D39

41.045

89.532

0.367
  htrA Streptococcus pneumoniae R6

41.045

89.532

0.367
  htrA Streptococcus pneumoniae TIGR4

41.045

89.532

0.367
  htrA Streptococcus mitis NCTC 12261

39.563

91.759

0.363