NTDB

Overview

Name	pilD	Type	Machinery gene
Locus tag	H7969_RS07950	Genome accession	NZ_CP060280
Coordinates	1586272..1587132 (+)	Length	286 a.a.
NCBI ID	WP_002220276.1	Uniprot ID	-
Organism	Neisseria meningitidis strain LNP24198
Function	assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1581272..1592132

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7969_RS07930 (H7969_07930)	dapD	1581782..1582603 (-)	822	WP_002220281.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
H7969_RS07935 (H7969_07935)	-	1582613..1582843 (-)	231	WP_025458514.1	hypothetical protein	-
H7969_RS07940 (H7969_07940)	pgi	1582813..1584456 (-)	1644	WP_002220279.1	glucose-6-phosphate isomerase	-
H7969_RS07945 (H7969_07945)	pilG	1584966..1586198 (+)	1233	WP_002220278.1	type 4 pilus assembly protein PilG	Machinery gene
H7969_RS07950 (H7969_07950)	pilD	1586272..1587132 (+)	861	WP_002220276.1	A24 family peptidase	Machinery gene
H7969_RS07955 (H7969_07955)	coaE	1587134..1587766 (+)	633	WP_002220275.1	dephospho-CoA kinase	-
H7969_RS07960 (H7969_07960)	-	1587759..1587968 (+)	210	WP_002212333.1	DNA gyrase inhibitor YacG	-
H7969_RS07965 (H7969_07965)	pilF	1588053..1589729 (-)	1677	WP_002220273.1	type IV-A pilus assembly ATPase PilB	Machinery gene
H7969_RS07975 (H7969_07975)	-	1590221..1590667 (-)	447	WP_002220271.1	DUF441 domain-containing protein	-
H7969_RS07980 (H7969_07980)	ispB	1590672..1591646 (-)	975	WP_002220270.1	octaprenyl diphosphate synthase	-

Sequence

Protein

Download Length: 286 a.a. Molecular weight: 31359.40 Da Isoelectric Point: 8.2213

                                >NTDB_id=475214 H7969_RS07950 WP_002220276.1 1586272..1587132(+) (pilD) [Neisseria meningitidis strain LNP24198]

MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW

QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP

LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV

AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide

Download Length: 861 bp

                                >NTDB_id=475214 H7969_RS07950 WP_002220276.1 1586272..1587132(+) (pilD) [Neisseria meningitidis strain LNP24198]

ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGCAGTTTCTTAAA

TGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA

CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGCCGCGTGCCGATACGCGCGTGG

CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCCTCCTGCCAAACCAAAATCAGCATACGCTATCC

CTTAATCGAACTGCTGACCGGCGTATTGTTCGGGCTGGTTGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT

TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC

TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG

CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC

TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC

GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT

TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(17-124)

Type IV leader peptidase family (Peptidase_A24)

(134-242)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
pilD	Neisseria gonorrhoeae MS11	96.14	99.65	0.958
pilD	Vibrio cholerae strain A1552	44.444	100	0.448
pilD	Vibrio campbellii strain DS40M4	44.928	96.503	0.434
pilD	Acinetobacter baumannii D1279779	46.97	92.308	0.434
pilD	Acinetobacter nosocomialis M2	46.97	92.308	0.434

Detailed information NTG0475214