Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   JR901_RS03540 Genome accession   NZ_CP070906
Coordinates   743490..744149 (-) Length   219 a.a.
NCBI ID   WP_001221486.1    Uniprot ID   -
Organism   Escherichia coli strain 88COLEC     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 738490..749149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JR901_RS03515 (JR901_03515) parE 738542..740434 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  JR901_RS03520 (JR901_03520) ygiN 740482..740796 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  JR901_RS03525 (JR901_03525) mdaB 740827..741408 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  JR901_RS03530 (JR901_03530) ygiZ 741766..742098 (+) 333 WP_000912091.1 DUF2645 family protein -
  JR901_RS03535 (JR901_03535) qseC 742144..743493 (-) 1350 WP_000673348.1 quorum sensing histidine kinase QseC -
  JR901_RS03540 (JR901_03540) ciaR 743490..744149 (-) 660 WP_001221486.1 quorum sensing response regulator transcription factor QseB Regulator
  JR901_RS03545 (JR901_03545) ygiW 744301..744693 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  JR901_RS03550 (JR901_03550) ygiV 744746..745228 (+) 483 WP_000183494.1 GyrI-like domain-containing protein -
  JR901_RS03555 (JR901_03555) ygiS 745337..746944 (+) 1608 WP_040234936.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24692.61 Da        Isoelectric Point: 6.3527

>NTDB_id=474860 JR901_RS03540 WP_001221486.1 743490..744149(-) (ciaR) [Escherichia coli strain 88COLEC]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGCQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=474860 JR901_RS03540 WP_001221486.1 743490..744149(-) (ciaR) [Escherichia coli strain 88COLEC]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTTGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365