Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   JOW61_RS07260 Genome accession   NZ_CP070844
Coordinates   1369387..1370736 (-) Length   449 a.a.
NCBI ID   WP_033881739.1    Uniprot ID   -
Organism   Bacillus subtilis subsp. natto strain BN0     
Function   degrading CSP; selective degradation of ComEA and ComEC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1364387..1375736
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JOW61_RS07240 (JOW61_07165) mhqA 1364587..1365537 (+) 951 WP_014479571.1 ring-cleaving dioxygenase -
  JOW61_RS07245 - 1365646..1365741 (+) 96 Protein_1363 hypothetical protein -
  JOW61_RS07250 (JOW61_07170) ykcB 1365754..1367904 (+) 2151 WP_014479572.1 glycosyltransferase family 39 protein -
  JOW61_RS07255 (JOW61_07175) ykcC 1367916..1368887 (+) 972 WP_014479573.1 glycosyltransferase family 2 protein -
  JOW61_RS07260 (JOW61_07180) htrA 1369387..1370736 (-) 1350 WP_033881739.1 serine protease HtrA Regulator
  JOW61_RS07265 (JOW61_07185) proG 1370905..1371723 (+) 819 WP_014479575.1 pyrroline-5-carboxylate reductase ProG -
  JOW61_RS07270 (JOW61_07190) dppA 1371853..1372677 (+) 825 WP_014479576.1 D-aminopeptidase DppA -
  JOW61_RS07275 (JOW61_07195) dppB 1372694..1373620 (+) 927 WP_003245446.1 dipeptide ABC transporter permease DppB -
  JOW61_RS07280 (JOW61_07200) dppC 1373626..1374588 (+) 963 WP_014479577.1 dipeptide ABC transporter permease DppC -
  JOW61_RS07285 (JOW61_07205) dppD 1374593..1375600 (+) 1008 WP_014479578.1 dipeptide ABC transporter ATP-binding subunit DppD -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 47728.87 Da        Isoelectric Point: 4.6021

>NTDB_id=474667 JOW61_RS07260 WP_033881739.1 1369387..1370736(-) (htrA) [Bacillus subtilis subsp. natto strain BN0]
MDNYRDENRTKGNENEVFLTKENDQSASYSARNVIHDQEKKKRGFGWFRPLLGGVIGGSLALGIYTFTPLGDHDSQDTAK
QSSSQQQTQSVTATSTSSESKKSSSSSSAFKSEDSSKISDMVEDLSPAIVGITNLQAQSNSSLFGSSSSDSSEDTESGSG
SGVIFKKENGKAYIITNNHVVEGASSLKVSLYDGTEVTAKLVGSDSLTDLAVLQISDDHVTKVANFGDSSDLRTGETVIA
IGDPLGKDLSRTVTQGIVSGVDRTVSMSTSAGETSINVIQTDAAINPGNSGGPLLNTDGKIVGINSMKISEDDVEGIGFA
IPSNDVKPIAEELLSKGQIERPYIGVSMLDLEQVPQNYQEGTLGLFGSQLNKGVYIREVASGSPAEKAGLKAEDIIIGLK
GKEIDTGSELRNILYKDAKIGETVEVKILRNGKEMTKKIKLDQKEEKTS

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=474667 JOW61_RS07260 WP_033881739.1 1369387..1370736(-) (htrA) [Bacillus subtilis subsp. natto strain BN0]
ATGGATAACTATCGTGATGAAAACAGAACGAAAGGTAATGAGAATGAGGTCTTTTTAACGAAAGAGAACGATCAGAGCGC
CTCCTACTCGGCCCGCAATGTCATTCATGATCAGGAGAAGAAAAAACGAGGATTCGGATGGTTCAGACCGTTGCTTGGCG
GAGTGATCGGCGGCAGTCTCGCCCTTGGCATTTACACGTTTACACCGCTTGGCGACCATGATTCTCAGGACACTGCAAAA
CAATCATCCAGCCAGCAGCAAACGCAATCTGTTACAGCAACAAGCACCTCCTCTGAATCTAAAAAAAGCTCAAGCAGCTC
ATCTGCATTCAAGAGCGAGGACTCTTCTAAAATCTCAGATATGGTAGAAGACCTTTCACCAGCGATTGTCGGTATTACAA
ATCTTCAGGCACAATCAAACAGCTCTTTGTTCGGCTCTAGTTCTTCTGATTCCAGCGAAGATACAGAAAGCGGTTCAGGG
TCAGGTGTCATTTTCAAAAAAGAGAATGGCAAGGCTTATATCATTACAAATAACCACGTCGTAGAAGGGGCATCATCACT
GAAGGTATCTTTATATGACGGCACTGAGGTTACTGCAAAGCTGGTAGGCAGTGACTCGTTAACTGATTTAGCCGTCCTCC
AAATCAGTGATGACCACGTCACAAAAGTGGCAAACTTCGGTGATTCATCTGATCTTAGAACAGGCGAGACCGTTATTGCG
ATTGGGGATCCGCTTGGAAAAGACCTGTCCCGCACAGTAACACAAGGAATTGTAAGCGGCGTGGACAGAACGGTTTCAAT
GTCTACATCAGCCGGCGAAACGAGCATTAACGTCATTCAGACAGACGCAGCAATTAATCCAGGTAACAGCGGCGGTCCTT
TGTTAAATACAGACGGCAAAATTGTCGGCATTAACAGTATGAAAATCAGTGAGGATGATGTTGAGGGCATCGGATTTGCC
ATTCCAAGCAATGACGTAAAACCGATTGCTGAAGAACTGCTGTCTAAAGGCCAAATTGAACGTCCATATATCGGTGTCAG
CATGCTTGATCTGGAACAAGTGCCGCAAAATTACCAAGAAGGCACACTCGGCCTGTTCGGCAGCCAGCTGAATAAAGGTG
TTTACATCCGTGAGGTCGCTTCAGGCTCTCCTGCTGAAAAGGCCGGATTAAAAGCGGAGGATATTATCATCGGCCTAAAA
GGTAAAGAAATTGATACAGGCAGTGAATTGCGCAATATCTTATATAAAGACGCAAAGATCGGTGAAACCGTTGAAGTGAA
AATTCTCCGAAACGGCAAAGAAATGACGAAAAAAATTAAACTTGATCAAAAAGAAGAGAAAACTTCGTAA

Domains

Predicted by InterProScan.

Trypsin-like peptidase domain (Trypsin_2)

(160-304)

PDZ domain (PDZ_2)

(342-441)

Peptidase family M50 (Peptidase_M50)

(366-448)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus pneumoniae Rx1

40.796

89.532

0.365
  htrA Streptococcus pneumoniae D39

40.796

89.532

0.365
  htrA Streptococcus pneumoniae R6

40.796

89.532

0.365
  htrA Streptococcus pneumoniae TIGR4

40.796

89.532

0.365
  htrA Streptococcus mitis NCTC 12261

39.32

91.759

0.361