Detailed information NTG0474181

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: H6X75_RS09775
• Genome accession: NZ_CP060156
• Coordinates: 1941610..1942620 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain PZ900700608
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1936610..1947620

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H6X75_RS09750 (H6X75_09745)	-	1936675..1937889 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
H6X75_RS09755 (H6X75_09750)	-	1938045..1938339 (-)	295	Protein_1922	hypothetical protein	-
H6X75_RS09760 (H6X75_09755)	-	1938501..1938953 (+)	453	WP_000079148.1	universal stress protein	-
H6X75_RS09765 (H6X75_09760)	-	1938988..1940376 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
H6X75_RS09770 (H6X75_09765)	-	1940442..1941404 (+)	963	WP_001124777.1	asparaginase	-
H6X75_RS09775 (H6X75_09770)	ccpA	1941610..1942620 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
H6X75_RS09780 (H6X75_09775)	-	1943045..1943644 (-)	600	WP_000866719.1	response regulator transcription factor	-
H6X75_RS09785 (H6X75_09780)	-	1943646..1944743 (-)	1098	WP_000893546.1	sensor histidine kinase	-
H6X75_RS09790 (H6X75_09785)	-	1944743..1945480 (-)	738	WP_000832834.1	ABC transporter permease	-
H6X75_RS09795 (H6X75_09790)	-	1945482..1946366 (-)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
H6X75_RS09800 (H6X75_09795)	-	1946353..1946547 (-)	195	WP_000820180.1	hypothetical protein	-
H6X75_RS09805 (H6X75_09800)	-	1946544..1946750 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=474181 H6X75_RS09775 WP_000990607.1 1941610..1942620(-) (ccpA) [Streptococcus pneumoniae strain PZ900700608]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=474181 H6X75_RS09775 WP_000990607.1 1941610..1942620(-) (ccpA) [Streptococcus pneumoniae strain PZ900700608]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568