Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA3   Type   Regulator
Locus tag   H6X75_RS01895 Genome accession   NZ_CP060156
Coordinates   353746..355728 (+) Length   660 a.a.
NCBI ID   WP_000842576.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700608     
Function   binding to XIP (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 335657..353424 353746..355728 flank 322
IS/Tn 353035..353424 353746..355728 flank 322


Gene organization within MGE regions


Location: 335657..355728
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H6X75_RS01805 (H6X75_01775) cps4A 336370..337815 (+) 1446 WP_000091060.1 capsular polysaccharide biosynthesis protein Cps4A -
  H6X75_RS01810 (H6X75_01780) cps4B 337817..338548 (+) 732 WP_000565370.1 capsular polysaccharide biosynthesis protein Cps4B -
  H6X75_RS01815 (H6X75_01785) cpsC 338557..339249 (+) 693 WP_000658143.1 capsular polysaccharide biosynthesis protein CpsC -
  H6X75_RS01820 (H6X75_01790) cpsD 339259..339942 (+) 684 WP_001142510.1 polysaccharide biosynthesis tyrosine autokinase CpsD -
  H6X75_RS01825 (H6X75_01795) - 339958..341325 (+) 1368 WP_000343580.1 sugar transferase -
  H6X75_RS01830 (H6X75_01800) - 341329..341778 (+) 450 WP_000861663.1 UDP-N-acetylglucosamine--LPS N-acetylglucosamine transferase -
  H6X75_RS01835 (H6X75_01805) - 341778..342281 (+) 504 WP_000578430.1 glycosyltransferase -
  H6X75_RS01840 (H6X75_01810) - 342271..343443 (+) 1173 WP_000702185.1 polysaccharide polymerase -
  H6X75_RS01845 (H6X75_01815) - 343440..344465 (+) 1026 WP_000573792.1 glycosyltransferase family 2 protein -
  H6X75_RS01850 (H6X75_01820) - 344473..345429 (+) 957 WP_000389753.1 glycosyltransferase -
  H6X75_RS01855 (H6X75_01825) - 345445..346353 (+) 909 WP_000570494.1 capsular polysaccharide synthesis protein -
  H6X75_RS01860 (H6X75_01830) - 346358..347821 (+) 1464 WP_000066240.1 flippase -
  H6X75_RS01865 (H6X75_01835) - 348187..349164 (+) 978 WP_000256585.1 acyltransferase -
  H6X75_RS01870 (H6X75_01840) - 349166..350314 (+) 1149 WP_000261152.1 CDP-glycerol--glycerophosphate glycerophosphotransferase -
  H6X75_RS01875 (H6X75_01845) - 350350..351378 (+) 1029 WP_000794265.1 iron-containing alcohol dehydrogenase family protein -
  H6X75_RS01880 (H6X75_01850) - 351394..352098 (+) 705 WP_000645462.1 phosphocholine cytidylyltransferase family protein -
  H6X75_RS01885 (H6X75_01855) - 352113..352946 (+) 834 WP_000779206.1 HAD-IIA family hydrolase -
  H6X75_RS01890 (H6X75_01860) - 353035..353427 (-) 393 Protein_373 transposase -
  H6X75_RS01895 (H6X75_01865) amiA3 353746..355728 (+) 1983 WP_000842576.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 73036.67 Da        Isoelectric Point: 4.7548

>NTDB_id=474133 H6X75_RS01895 WP_000842576.1 353746..355728(+) (amiA3) [Streptococcus pneumoniae strain PZ900700608]
MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDPDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPS
MAEDWSVSKDGLTYTYTIRKDAKWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGPYLLKSIVTKSSVEFAKNPNYWD
KDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARLYPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSK
TSDEQKASTKKALLNKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVTYGDEWKDV
NLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQRVQSMKQSLEATLGADNVIIDIQQLQKDEV
NNITYFAENAAGEDWDLSDNVGWGPDFADPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEAT
DVAKRYDKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQDKAVTVDEYQKAQEKW
MKEKEESNKKAQEDLAKHVK

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=474133 H6X75_RS01895 WP_000842576.1 353746..355728(+) (amiA3) [Streptococcus pneumoniae strain PZ900700608]
ATGAAAAGTTCAAAACTATTTGCCCTTGCGGGCGTGACATTATTGGCGGCGACTACTTTAGCTGCATGCTCTGGATCAGG
TTCAAGTACTAAAGGTGAGAAGACATTCTCATACATTTATGAGACAGACCCTGATAACCTCAACTATTTGACAACTGCTA
AGGCTGCGACAGCAAATATTACCAGTAACGTGGTTGATGGTTTGCTAGAAAATGATCGCTACGGGAACTTTGTGCCGTCT
ATGGCTGAGGATTGGTCTGTATCCAAGGATGGATTGACTTACACTTATACTATCCGTAAGGATGCAAAATGGTATACTTC
TGAAGGTGAAGAATACGCGGCAGTCAAAGCTCAAGACTTTGTAACAGGACTAAAATATGCTGCTGATAAAAAATCAGATG
CTCTTTACCTTGTTCAAGAATCAATCAAAGGGTTGGATGCCTATGTAAAAGGGGAAATCAAAGATTTCTCACAAGTAGGA
ATTAAGGCTCTGGATGAACAGACAGTTCAGTACACTTTGAACAAACCAGAAAGCTTCTGGAATTCTAAGACAACCATGGG
TGTGCTTGCGCCAGTTAATGAAGAGTTTTTGAATTCAAAAGGGGATGATTTTGCCAAAGCTACGGATCCAAGTAGTCTCT
TGTATAACGGTCCTTATTTGTTGAAATCCATTGTGACCAAATCTTCTGTTGAATTTGCGAAAAATCCGAACTACTGGGAT
AAGGACAATGTGCATATTGACAAAGTTAAATTGTCATTCTGGGATGGTCAAGATACCAGCAAACCTGCAGAAAACTTTAA
AGATGGTAGCCTTACAGCAGCTCGTCTCTATCCAACAAGTGCAAGTTTCGCAGAGCTTGAGAAGAGTATGAAGGACAATA
TTGTCTATACTCAACAAGACTCTATTACGTATCTAGTTGGTACAAATATTGACCGTCAGTCCTATAAATACACATCTAAG
ACCAGCGATGAACAAAAGGCATCGACTAAAAAGGCTCTCTTAAACAAGGATTTCCGTCAGGCTATTGCCTTTGGTTTTGA
TCGTACAGCCTATGCCTCTCAGTTGAATGGACAAACTGGAGCAAGCAAAATCTTACGTAATATCTTTGTTCCACCAACAT
TTGTTCAAGCAGATGGTAAAAACTTTGGCGATATGGTCAAAGAGAAATTGGTCACTTATGGGGATGAATGGAAGGATGTT
AATCTTGCAGATTCTCAGGATGGTCTTTACAATCCAGAAAAAGCCAAGGCTGAATTTGCTAAAGCTAAATCAGCCTTACA
AGCAGAAGGTGTGACATTCCCAATTCATTTGGATATGCCAGTTGACCAAACAGCAACTACAAAAGTTCAGCGCGTCCAAT
CTATGAAACAATCCTTGGAAGCAACTTTAGGAGCTGATAATGTCATTATTGATATCCAACAACTACAAAAAGACGAAGTA
AACAATATTACATATTTTGCTGAAAATGCTGCTGGCGAAGACTGGGATTTATCAGATAATGTCGGTTGGGGTCCAGACTT
TGCCGATCCATCAACCTACCTTGATATCATCAAACCATCTGTAGGAGAAAGTACTAAAACATATTTAGGGTTTGACTCAG
GGGAAGATAATGTAGCTGCTAAAAAAGTAGGTCTATATGACTACGAAAAATTGGTTACTGAGGCTGGTGATGAGGCTACA
GATGTTGCTAAACGCTATGATAAATACGCTGCAGCCCAAGCTTGGTTGACAGATAGTGCTTTGATTATTCCAACTACATC
TCGTACAGGGCGTCCAATTTTGTCTAAGATGGTACCATTTACAATACCATTTGCATTGTCAGGAAATAAAGGTACAAGTG
AACCAGTCTTGTATAAATACTTGGAACTTCAAGACAAGGCAGTCACTGTAGATGAATACCAAAAAGCTCAGGAAAAATGG
ATGAAAGAAAAAGAAGAGTCTAATAAAAAGGCTCAAGAAGATCTCGCAAAACATGTGAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(77-519)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA3 Streptococcus thermophilus LMD-9

58.245

100

0.583
  amiA3 Streptococcus thermophilus LMG 18311

57.943

100

0.58
  amiA Streptococcus salivarius strain HSISS4

57.791

100

0.579