Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   I6K28_RS18400 Genome accession   NZ_CP070115
Coordinates   3852041..3853873 (+) Length   610 a.a.
NCBI ID   WP_050019175.1    Uniprot ID   -
Organism   Escherichia coli strain FDAARGOS_1298     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3847041..3858873
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K28_RS18365 (I6K28_18325) dcyD 3847267..3848253 (+) 987 WP_050019174.1 D-cysteine desulfhydrase -
  I6K28_RS18370 (I6K28_18330) tcyL 3848268..3848936 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  I6K28_RS18375 (I6K28_18335) tcyN 3848933..3849685 (+) 753 WP_001273001.1 L-cystine ABC transporter ATP-binding protein TcyN -
  I6K28_RS18380 (I6K28_18340) sdiA 3849915..3850637 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  I6K28_RS18385 (I6K28_18345) yecF 3850705..3850929 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  I6K28_RS18390 (I6K28_18350) yecU 3850916..3851092 (-) 177 WP_001307856.1 protein YecU -
  I6K28_RS18395 (I6K28_18355) letA 3851388..3852044 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  I6K28_RS18400 (I6K28_18360) uvrC 3852041..3853873 (+) 1833 WP_050019175.1 excinuclease ABC subunit UvrC Machinery gene
  I6K28_RS18405 (I6K28_18365) pgsA 3853930..3854478 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  I6K28_RS18425 (I6K28_18385) yecA 3855128..3855793 (+) 666 WP_000847882.1 UPF0149 family protein YecA -
  I6K28_RS18430 (I6K28_18390) tyrP 3855844..3857055 (-) 1212 WP_000797555.1 tyrosine transporter TyrP -
  I6K28_RS18435 (I6K28_18395) yecH 3857246..3857485 (+) 240 WP_000377224.1 YecH family metal-binding protein -
  I6K28_RS18440 (I6K28_18400) ftnA 3857523..3858020 (-) 498 WP_000917208.1 non-heme ferritin -
  I6K28_RS18445 (I6K28_18405) yecR 3858192..3858515 (-) 324 WP_001237882.1 YecR-like lipofamily protein -
  I6K28_RS18450 (I6K28_18410) azuC 3858779..3858865 (+) 87 WP_010723106.1 stress response protein AzuC -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68244.14 Da        Isoelectric Point: 9.3685

>NTDB_id=472916 I6K28_RS18400 WP_050019175.1 3852041..3853873(+) (uvrC) [Escherichia coli strain FDAARGOS_1298]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGSTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALISKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGIGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=472916 I6K28_RS18400 WP_050019175.1 3852041..3853873(+) (uvrC) [Escherichia coli strain FDAARGOS_1298]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTACTG
GAACACAACTACATCAAACTTTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCATATCCTTTTATCTTCCT
GAGTGGCGATACCCACCCGCGTCTGGCGATGCATCGTGGAGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAACAGTGTTTATCGC
AACCGCTCGCGTCCGTGTCTGCAATATCAGATAGGGCGCTGTCTGGGGCCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCGGCGCGGATTCGCGACCAAATTCAGGCGGTGCGACGTGTCACC
GAAAAACAGTTTGTTTCCAATACCGGCGACGACCTTGACGTTATTGGAGTGGCGTTCGATGCGGGTATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCAGTACGGAACTGAGCG
AGGTGGTGGAAACCTTCGTAGGTCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGTGGCGATAGAGCGCGTTATCTGAAACTCGCGCGTACCAATGCGGCGACGGCCTTAATCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGGCTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGTGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACTGGCATCACACCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TTGACGACAGTAAGATCCCGGATGTGATCCTTATAGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTTAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACACGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCATCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGTGGTTTGCAAGGTTTACGTAACGCCAGCGT
TGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)

Helix-hairpin-helix domain (HHH_5)

(558-609)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.891

99.508

0.377
  uvrC Streptococcus pneumoniae R6

37.562

99.508

0.374
  uvrC Streptococcus pneumoniae D39

37.562

99.508

0.374