Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   I6K28_RS18395 Genome accession   NZ_CP070115
Coordinates   3851388..3852044 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain FDAARGOS_1298     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3846388..3857044
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K28_RS18365 (I6K28_18325) dcyD 3847267..3848253 (+) 987 WP_050019174.1 D-cysteine desulfhydrase -
  I6K28_RS18370 (I6K28_18330) tcyL 3848268..3848936 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  I6K28_RS18375 (I6K28_18335) tcyN 3848933..3849685 (+) 753 WP_001273001.1 L-cystine ABC transporter ATP-binding protein TcyN -
  I6K28_RS18380 (I6K28_18340) sdiA 3849915..3850637 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  I6K28_RS18385 (I6K28_18345) yecF 3850705..3850929 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  I6K28_RS18390 (I6K28_18350) yecU 3850916..3851092 (-) 177 WP_001307856.1 protein YecU -
  I6K28_RS18395 (I6K28_18355) letA 3851388..3852044 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  I6K28_RS18400 (I6K28_18360) uvrC 3852041..3853873 (+) 1833 WP_050019175.1 excinuclease ABC subunit UvrC Machinery gene
  I6K28_RS18405 (I6K28_18365) pgsA 3853930..3854478 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  I6K28_RS18425 (I6K28_18385) yecA 3855128..3855793 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=472915 I6K28_RS18395 WP_000611328.1 3851388..3852044(+) (letA) [Escherichia coli strain FDAARGOS_1298]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=472915 I6K28_RS18395 WP_000611328.1 3851388..3852044(+) (letA) [Escherichia coli strain FDAARGOS_1298]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482