Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   I6K28_RS07890 Genome accession   NZ_CP070115
Coordinates   1636559..1637149 (+) Length   196 a.a.
NCBI ID   WP_001332271.1    Uniprot ID   A0A0H2Z4C4
Organism   Escherichia coli strain FDAARGOS_1298     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1631559..1642149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K28_RS07860 (I6K28_07840) yidG 1631851..1632213 (+) 363 WP_001113443.1 DUF202 domain-containing protein -
  I6K28_RS07865 (I6K28_07845) yidF 1632210..1632707 (+) 498 WP_000148034.1 radical SAM protein -
  I6K28_RS07870 (I6K28_07850) emrD 1632715..1633899 (-) 1185 WP_001332269.1 multidrug efflux MFS transporter EmrD -
  I6K28_RS26240 ysdE 1633981..1634055 (+) 75 WP_211180519.1 protein YsdE -
  I6K28_RS07875 (I6K28_07855) ivbL 1634300..1634398 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  I6K28_RS07880 (I6K28_07860) ilvB 1634504..1636192 (+) 1689 WP_000168473.1 acetolactate synthase large subunit -
  I6K28_RS07885 (I6K28_07865) ilvN 1636196..1636486 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  I6K28_RS07890 (I6K28_07870) letA 1636559..1637149 (+) 591 WP_001332271.1 transcriptional regulator UhpA Regulator
  I6K28_RS07895 (I6K28_07875) uhpB 1637149..1638651 (+) 1503 WP_001332272.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  I6K28_RS07900 (I6K28_07880) uhpC 1638661..1639980 (+) 1320 WP_001350834.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  I6K28_RS07905 (I6K28_07885) uhpT 1640118..1641509 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20836.26 Da        Isoelectric Point: 5.6059

>NTDB_id=472874 I6K28_RS07890 WP_001332271.1 1636559..1637149(+) (letA) [Escherichia coli strain FDAARGOS_1298]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGCGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=472874 I6K28_RS07890 WP_001332271.1 1636559..1637149(+) (letA) [Escherichia coli strain FDAARGOS_1298]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGTGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCCGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(136-191)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2Z4C4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378