Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Machinery gene
Locus tag   R2846_RS00735 Genome accession   NC_017452
Coordinates   143402..143815 (+) Length   137 a.a.
NCBI ID   WP_014550413.1    Uniprot ID   -
Organism   Haemophilus influenzae R2846     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 138402..148815
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R2846_RS00715 (R2846_0140) - 138890..141484 (-) 2595 WP_014550411.1 penicillin-binding protein 1A -
  R2846_RS00720 (R2846_0141) comA 141583..142380 (+) 798 WP_013527435.1 pilus assembly protein PilM Machinery gene
  R2846_RS00725 (R2846_0142) comB 142381..142887 (+) 507 WP_014550412.1 competence protein ComB Machinery gene
  R2846_RS00730 (R2846_0143) comC 142884..143405 (+) 522 WP_005662592.1 competence protein ComC Machinery gene
  R2846_RS00735 (R2846_0144) comD 143402..143815 (+) 414 WP_014550413.1 pilus assembly protein PilP Machinery gene
  R2846_RS00740 (R2846_0145) comE 143825..145162 (+) 1338 WP_014550414.1 type IV pilus secretin PilQ family protein Machinery gene
  R2846_RS00745 (R2846_0146) - 145175..145861 (+) 687 WP_014550415.1 ComF family protein -
  R2846_RS00750 (R2846_0147) nfuA 145937..146533 (+) 597 WP_005656459.1 Fe-S biogenesis protein NfuA -
  R2846_RS00755 (R2846_0148) nudC 146600..147394 (+) 795 WP_014550416.1 NAD(+) diphosphatase -
  R2846_RS00760 (R2846_0149) - 147430..148020 (+) 591 WP_005656455.1 YjaG family protein -
  R2846_RS00765 (R2846_0150) - 148160..148432 (+) 273 WP_014550417.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 137 a.a.        Molecular weight: 15630.67 Da        Isoelectric Point: 4.2602

>NTDB_id=47287 R2846_RS00735 WP_014550413.1 143402..143815(+) (comD) [Haemophilus influenzae R2846]
MKYWFFLTALLFINCTWGQDPFDKTQRNRSQFDNAQTVMEQTEIISSDVPNNLCGADENRQAAEIPLNALKLVGVVISED
KAFALLQDQALQVYSVLEGVDVAQEGYIVEKINQNNVQFMRKLGEQCDSSEWKKLSF

Nucleotide


Download         Length: 414 bp        

>NTDB_id=47287 R2846_RS00735 WP_014550413.1 143402..143815(+) (comD) [Haemophilus influenzae R2846]
ATGAAGTATTGGTTTTTCCTAACAGCATTGCTTTTTATAAATTGCACTTGGGGACAAGATCCTTTCGATAAAACACAGCG
TAACCGTTCTCAGTTTGATAACGCACAAACAGTAATGGAACAGACAGAAATAATTTCCTCAGATGTACCTAATAATCTAT
GCGGAGCGGATGAAAATCGCCAAGCGGCTGAAATTCCTTTGAACGCTTTAAAATTGGTGGGCGTAGTGATTTCTGAAGAT
AAAGCCTTTGCCTTATTGCAAGATCAGGCTTTGCAAGTTTACAGCGTTTTAGAGGGCGTTGATGTGGCTCAAGAGGGCTA
TATTGTAGAAAAAATCAACCAAAACAATGTTCAATTTATGCGCAAGCTCGGAGAGCAATGTGATAGTAGTGAATGGAAAA
AATTAAGTTTTTAA

Domains

Predicted by InterproScan.

Pilus assembly protein, PilP (PilP)

(26-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Haemophilus influenzae Rd KW20

94.161

100

0.942
  comD Haemophilus influenzae 86-028NP

93.431

100

0.934

Multiple sequence alignment