Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   R2866_RS07145 Genome accession   NC_017451
Coordinates   1465375..1466049 (-) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae R2866     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1460375..1471049
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R2866_RS07125 (R2866_1420) hinT 1462082..1462432 (+) 351 WP_005627389.1 purine nucleoside phosphoramidase -
  R2866_RS07130 (R2866_1421) - 1462432..1462782 (+) 351 WP_005647993.1 YcfL family protein -
  R2866_RS07135 (R2866_1422) nagZ 1462786..1463838 (+) 1053 WP_020910155.1 beta-N-acetylhexosaminidase -
  R2866_RS07140 (R2866_1423) rlmC 1463835..1465010 (+) 1176 WP_005647997.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  R2866_RS07145 (R2866_1424) crp 1465375..1466049 (-) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  R2866_RS07150 (R2866_1425) - 1466034..1466285 (-) 252 WP_005647999.1 YheU family protein -
  R2866_RS07155 (R2866_1426) slmA 1466307..1466963 (-) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  R2866_RS07160 (R2866_1427) dut 1466967..1467422 (-) 456 WP_005631431.1 dUTP diphosphatase -
  R2866_RS07165 (R2866_1428) coaBC 1467470..1468672 (-) 1203 WP_005666020.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  R2866_RS07170 (R2866_1429) radC 1468836..1469501 (+) 666 WP_020910156.1 RadC family protein -
  R2866_RS07175 (R2866_1430) rpmB 1469715..1469951 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  R2866_RS07180 (R2866_1431) rpmG 1469963..1470133 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=47269 R2866_RS07145 WP_005647998.1 1465375..1466049(-) (crp) [Haemophilus influenzae R2866]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=47269 R2866_RS07145 WP_005647998.1 1465375..1466049(-) (crp) [Haemophilus influenzae R2866]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCTGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment