Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   I6K87_RS07930 Genome accession   NZ_CP069892
Coordinates   1608846..1610792 (+) Length   648 a.a.
NCBI ID   WP_049533450.1    Uniprot ID   -
Organism   Streptococcus anginosus strain FDAARGOS_1357     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1603846..1615792
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K87_RS07910 (I6K87_07910) argR 1604123..1604563 (+) 441 WP_003027809.1 arginine repressor -
  I6K87_RS07915 (I6K87_07915) hexA 1604936..1607497 (+) 2562 WP_204982533.1 DNA mismatch repair protein MutS Machinery gene
  I6K87_RS07920 (I6K87_07920) - 1607686..1608144 (-) 459 WP_003027807.1 DUF3021 domain-containing protein -
  I6K87_RS07925 (I6K87_07925) brsR 1608141..1608581 (-) 441 WP_049533411.1 LytTR family DNA-binding domain-containing protein Regulator
  I6K87_RS07930 (I6K87_07930) hexB 1608846..1610792 (+) 1947 WP_049533450.1 DNA mismatch repair endonuclease MutL Machinery gene
  I6K87_RS07935 (I6K87_07935) ruvA 1610926..1611516 (+) 591 WP_204982534.1 Holliday junction branch migration protein RuvA Machinery gene
  I6K87_RS07940 (I6K87_07940) - 1611526..1612080 (+) 555 WP_049533427.1 DNA-3-methyladenine glycosylase I -
  I6K87_RS10075 - 1612085..1612171 (+) 87 Protein_1524 CPBP family intramembrane glutamate endopeptidase -
  I6K87_RS07945 (I6K87_07945) - 1612269..1612679 (-) 411 WP_049533428.1 helix-turn-helix domain-containing protein -
  I6K87_RS07950 (I6K87_07950) cinA 1612949..1614217 (+) 1269 WP_049533429.1 competence/damage-inducible protein A Machinery gene
  I6K87_RS07955 (I6K87_07955) recA 1614265..1615410 (+) 1146 WP_049533430.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 648 a.a.        Molecular weight: 73122.19 Da        Isoelectric Point: 5.1688

>NTDB_id=471035 I6K87_RS07930 WP_049533450.1 1608846..1610792(+) (hexB) [Streptococcus anginosus strain FDAARGOS_1357]
MSKIIELPENLANQIAAGEVIERPSSVAKELVENSIDAGASQITIEIEEAGLKSIQVIDNGEGIEHEEVSLALRRHATSK
IKKQADLFRIRTLGFRGEALPSIASVSRLTIETATNGGTHGTLLIAQGGEIETIEPSSCPRGTKIKVEDLFFNTPARLKY
MKSQQAELSHIVDVMNRLSLAHPEVAFILLNDGKELTRTAGTGNLRQAIAGIYGLTTAKKMIEISASDLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIRIDPYLADVNVHPTKQEVRISKERELMALISQ
AISASLREQDLIPDALENLAKSTINRANKPEQTSLPLKANRLYYDKERNDFFVKPQVSEAQPSFEESARLDQQSADTDEL
NSKVASVKFAERQSPSYNQLDHPELDQASLERALDKLGGEETSTFPELEYFGQMHGTYLFAQGNGGLYIIDQHAAQERVK
YEYYREKIGDVDASQQQLLVPYIFEFPADDMLRLKQRMTLLEEVGVFLEEYGTNQFILREHPIWLKEEEIESGIYEMCDM
LLLTKEVSIKKYRAELAIMMSCKRSIKANHSLDDYSARDLIFQLSQCDNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHT
SLRELGKY

Nucleotide


Download         Length: 1947 bp        

>NTDB_id=471035 I6K87_RS07930 WP_049533450.1 1608846..1610792(+) (hexB) [Streptococcus anginosus strain FDAARGOS_1357]
ATGTCAAAAATTATAGAACTACCAGAAAATCTTGCCAATCAGATTGCGGCAGGTGAGGTCATTGAGCGGCCTAGCAGCGT
TGCCAAAGAGTTGGTAGAAAATTCTATTGACGCGGGCGCTAGCCAAATTACAATTGAGATTGAAGAAGCGGGACTCAAGA
GCATTCAAGTCATTGATAATGGCGAAGGAATTGAGCATGAGGAGGTTTCCTTGGCTTTGCGGCGGCATGCTACTAGTAAA
ATCAAGAAACAAGCCGACCTTTTTCGAATTCGGACATTGGGCTTTCGCGGTGAAGCGCTTCCGTCGATTGCTTCTGTTTC
ACGCTTGACAATTGAAACTGCGACAAATGGTGGAACACATGGAACGCTTCTGATTGCGCAAGGTGGAGAAATTGAAACTA
TAGAACCAAGTAGCTGTCCTAGAGGCACCAAAATCAAGGTGGAAGATCTCTTTTTCAACACACCTGCTCGCTTAAAATAT
ATGAAAAGTCAACAAGCAGAACTGTCTCACATTGTAGATGTAATGAACCGTTTGAGTCTAGCACATCCAGAGGTCGCTTT
TATCTTGCTCAATGATGGTAAAGAGTTGACTCGGACGGCAGGAACAGGAAATTTGCGTCAAGCAATTGCTGGTATCTATG
GATTAACAACAGCAAAAAAAATGATTGAAATTTCAGCATCTGATTTGGATTTTGAAGTATCAGGCTATATTAGTTTGCCA
GAATTAACAAGGGCTAATCGGAATTACATTACTATCCTCATCAATGGTCGCTACATCAAGAATTTCCTACTCAATCGAGC
TATTTTAGATGGATATGGTAGCAAGCTCATGGTGGGACGTTTTCCGATCGCTGTGATTGATATTCGGATTGACCCATATC
TTGCTGATGTCAATGTTCACCCGACCAAGCAAGAAGTGCGGATTTCAAAAGAGAGAGAACTGATGGCCTTGATTTCGCAA
GCCATTTCTGCGAGTTTAAGAGAGCAGGATTTGATTCCGGACGCTTTGGAAAATTTAGCAAAATCAACCATTAACCGAGC
AAATAAACCTGAGCAGACGAGTCTCCCACTCAAAGCAAACCGACTCTATTACGATAAAGAAAGAAATGACTTCTTTGTGA
AACCACAAGTGTCAGAAGCTCAACCTTCTTTTGAGGAATCTGCCCGATTAGACCAACAATCTGCTGATACAGATGAACTC
AATTCAAAAGTTGCTTCTGTCAAATTTGCAGAAAGGCAATCTCCTTCTTACAATCAACTAGATCATCCAGAGCTGGATCA
GGCGAGCTTAGAGAGAGCTTTAGATAAGTTGGGTGGAGAAGAAACTTCAACGTTTCCAGAATTGGAATATTTCGGGCAAA
TGCACGGCACCTACCTTTTTGCTCAAGGAAACGGTGGTCTTTATATTATTGACCAACATGCAGCTCAAGAGCGAGTAAAG
TATGAATATTACCGCGAAAAAATCGGAGATGTAGATGCTAGTCAGCAGCAGCTTCTGGTTCCCTATATCTTTGAATTTCC
AGCTGATGATATGTTGCGTCTGAAACAACGAATGACTCTTTTAGAAGAAGTCGGTGTTTTCCTTGAAGAATACGGAACTA
ATCAATTTATTCTTCGTGAACATCCCATTTGGCTTAAGGAAGAGGAGATCGAATCAGGTATTTATGAGATGTGCGATATG
CTGCTTCTAACCAAGGAAGTCTCTATCAAGAAATATCGCGCTGAGCTAGCTATTATGATGAGTTGCAAACGCTCTATTAA
AGCCAATCACAGTTTGGATGACTATTCAGCGCGTGATTTGATTTTTCAGTTATCACAATGTGACAATCCCTACAATTGTC
CACATGGTCGTCCCGTTTTGGTCAACTTTACCAAATCTGATATGGAAAAAATGTTCCGTCGGATTCAGGAAAATCATACC
AGTCTGAGAGAATTGGGGAAATACTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(26-118)

MutL C terminal dimerisation domain (MutL_C)

(450-592)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

76.888

100

0.77