Detailed information NTG0471033

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: I6K87_RS07915
• Genome accession: NZ_CP069892
• Coordinates: 1604936..1607497 (+)
• Length: 853 a.a.
• NCBI ID: WP_204982533.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain FDAARGOS_1357
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1599936..1612497

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6K87_RS07895 (I6K87_07895)	-	1601236..1601745 (+)	510	WP_003027812.1	ABC transporter permease	-
I6K87_RS07900 (I6K87_07900)	nrdI	1601821..1602276 (+)	456	WP_003027811.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
I6K87_RS07905 (I6K87_07905)	argS	1602331..1604019 (-)	1689	WP_059221617.1	arginine--tRNA ligase	-
I6K87_RS07910 (I6K87_07910)	argR	1604123..1604563 (+)	441	WP_003027809.1	arginine repressor	-
I6K87_RS07915 (I6K87_07915)	hexA	1604936..1607497 (+)	2562	WP_204982533.1	DNA mismatch repair protein MutS	Machinery gene
I6K87_RS07920 (I6K87_07920)	-	1607686..1608144 (-)	459	WP_003027807.1	DUF3021 domain-containing protein	-
I6K87_RS07925 (I6K87_07925)	brsR	1608141..1608581 (-)	441	WP_049533411.1	LytTR family DNA-binding domain-containing protein	Regulator
I6K87_RS07930 (I6K87_07930)	hexB	1608846..1610792 (+)	1947	WP_049533450.1	DNA mismatch repair endonuclease MutL	Machinery gene
I6K87_RS07935 (I6K87_07935)	ruvA	1610926..1611516 (+)	591	WP_204982534.1	Holliday junction branch migration protein RuvA	Machinery gene
I6K87_RS07940 (I6K87_07940)	-	1611526..1612080 (+)	555	WP_049533427.1	DNA-3-methyladenine glycosylase I	-
I6K87_RS10075	-	1612085..1612171 (+)	87	Protein_1524	CPBP family intramembrane glutamate endopeptidase	-

Sequence

Protein

• Length: 853 a.a.
• Molecular weight: 96031.75 Da
• Isoelectric Point: 4.9649

>NTDB_id=471033 I6K87_RS07915 WP_204982533.1 1604936..1607497(+) (hexA) [Streptococcus anginosus strain FDAARGOS_1357]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDATNAAQILEIALTSRNKNSENPIPMAGVPYHSVQQYIDVLI
EAGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVALDKLAGIYGLAYMDVGTGEFQVTTLSDFNM
VCGEIRNLRAREVVIGYELPEMERQVLETQMNLLLSQVETTFDDVQLLGKDLSPLEHQVAGKLLEYVHKTQLRELSHLKQ
VHHYEIKDFLQMDYSTMASLDLTENARTGKKHGSLYWLMDETKTAMGTRLLRAWIQRPLIDKERIVKRQDVVQVFLDHFF
ERSDLADSLKGVYDIERLASRVSFGKTNPKDLLQLAATLSNVPQIKGILKGIDSLVLEDLIAKLDEIPELAALIQSAISS
DAPNVITEGNIIKTGFDETLDKYRVVMRDGTSWIADIEAKERETSGINNLKIDYNKKDGYYFHVTNSQLEHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEAGKYIKRLQFLAQTLATVDVLQSFATVAEKQHFVRPEFI
EQRSIQIDKGRHAVVEKVMGAQTYIPNSISMDENVNVQLITGPNMSGKSTYMRQLAIIVIMAQMGSYVSAESAQLSIFDA
IFTRIGAADDLVSGQSTFMVEMMEANHAISQATENSLILFDELGRGTATYDGMALAQAIIEYIHNRTGSKTLFATHYHEL
TELSTSLTQLENVHVATLEKDGQVTFLHKIEVGPADKSYGIHVAKIAGLPNDLLTRADQILTRLESQANEKSSLGISNTL
PADAREKNQVAEQMSLFPEITESPILDELRQLDIYNMTPMEVMLAVAEMKKKL

Nucleotide

• Length: 2562 bp

>NTDB_id=471033 I6K87_RS07915 WP_204982533.1 1604936..1607497(+) (hexA) [Streptococcus anginosus strain FDAARGOS_1357]
ATGACAAAAGAAAAACTATCTCCAGGAATGCAACAGTATTTAGATATAAAAAAAGATTATCCAGATGCTTTTTTGTTGTT
TCGCATGGGAGATTTTTATGAATTATTCTATGATGATGCGACCAATGCGGCACAGATTTTAGAGATTGCTCTGACTAGCC
GCAATAAAAACTCGGAAAATCCAATCCCAATGGCAGGAGTTCCTTATCATTCGGTGCAGCAATACATTGATGTCTTAATT
GAAGCAGGCTATAAAGTTGCGATTGCAGAGCAAATGGAAGATCCTAAAAAAGCGGTTGGAGTAGTCAAACGTGAAGTGGT
GCAGGTCATCACGCCGGGGACAGTAGTTGATTCTTCAAAGCCAGACAGTCAGAACAACTTTTTAGTGGCTTTAGATAAGC
TGGCAGGTATATATGGGCTGGCTTATATGGATGTGGGAACAGGTGAATTTCAAGTTACAACTCTCAGTGATTTTAACATG
GTCTGTGGAGAAATCCGAAACCTACGAGCGCGTGAAGTGGTCATAGGGTATGAATTGCCTGAAATGGAGCGTCAAGTATT
GGAGACTCAAATGAATCTCCTTTTATCGCAAGTAGAAACTACATTTGATGATGTTCAGCTACTAGGAAAGGACTTGTCGC
CGCTAGAGCACCAAGTAGCTGGAAAGTTATTAGAGTATGTTCATAAAACGCAGCTACGTGAGCTTAGTCATTTGAAACAA
GTTCATCATTATGAAATCAAAGATTTCTTGCAGATGGACTACTCAACTATGGCAAGTCTGGATTTAACAGAGAATGCTCG
GACAGGAAAGAAGCACGGTAGCCTTTATTGGTTGATGGATGAGACCAAGACAGCTATGGGAACGCGATTGTTGAGAGCGT
GGATTCAACGTCCGTTGATTGATAAAGAGCGAATCGTCAAGCGGCAGGATGTAGTGCAAGTCTTTTTAGATCATTTCTTT
GAGCGCAGTGATTTAGCAGATAGTCTCAAAGGTGTGTATGACATTGAGCGTTTAGCCAGTCGTGTTTCGTTTGGCAAGAC
CAATCCGAAAGATTTATTGCAGTTGGCAGCAACATTGAGCAATGTCCCTCAGATTAAGGGAATTTTAAAAGGAATTGACA
GCCTAGTTTTGGAAGATTTGATTGCCAAATTGGATGAAATTCCTGAATTAGCGGCCTTGATTCAGTCAGCAATTTCGTCG
GATGCTCCAAATGTCATTACAGAGGGTAATATTATTAAAACAGGTTTTGATGAAACTTTGGACAAGTATCGAGTGGTCAT
GCGAGATGGAACGAGTTGGATTGCAGATATTGAGGCGAAAGAAAGAGAAACTAGTGGAATTAACAACCTGAAGATTGATT
ACAATAAAAAAGATGGTTATTATTTCCATGTCACCAATTCCCAGCTTGAACACGTTCCCAGTCATTTTTTCCGCAAAGCA
ACTTTGAAAAATTCGGAGCGTTTTGGTACGGAAGAACTGGCTCGTATTGAAGGCGAGATGTTGGAAGCGCGTGAAAAATC
AGCTAATTTGGAATACGAGATTTTTATGCGCATTCGTGAGGAAGCTGGTAAATATATCAAACGCCTGCAATTCTTGGCGC
AAACTCTGGCAACAGTTGATGTGCTGCAAAGCTTTGCAACTGTAGCTGAAAAGCAACACTTTGTGAGACCAGAATTTATT
GAGCAGCGCTCTATCCAAATTGATAAAGGGCGGCATGCGGTTGTAGAAAAAGTTATGGGTGCACAAACCTATATTCCTAA
CAGCATTTCAATGGACGAGAATGTTAATGTTCAGCTAATTACAGGTCCAAATATGAGTGGGAAGTCAACTTATATGCGGC
AGTTAGCAATCATTGTGATTATGGCTCAAATGGGCTCTTATGTTTCAGCTGAAAGCGCTCAATTGTCGATTTTTGATGCA
ATCTTTACTCGAATTGGTGCAGCGGATGACTTGGTTTCTGGACAATCAACCTTTATGGTTGAAATGATGGAAGCGAACCA
TGCTATTTCTCAAGCAACAGAAAATTCACTCATTCTTTTCGATGAGTTAGGAAGAGGAACAGCGACCTATGATGGCATGG
CGCTTGCTCAGGCGATTATTGAGTATATTCACAATCGGACAGGCTCCAAGACACTTTTTGCGACTCACTATCACGAGTTG
ACAGAACTGTCAACTAGCTTGACACAACTAGAAAATGTCCATGTAGCAACCCTAGAAAAAGATGGTCAAGTAACATTTCT
TCATAAGATTGAAGTTGGACCTGCTGATAAATCTTATGGGATTCATGTAGCAAAAATTGCAGGTTTGCCAAATGATTTGT
TGACAAGAGCGGATCAAATATTGACACGATTAGAAAGCCAAGCAAATGAGAAGTCATCTCTTGGCATCTCTAATACATTG
CCTGCGGATGCTCGTGAAAAAAATCAAGTGGCTGAGCAGATGTCTTTATTTCCAGAAATAACCGAATCACCTATTTTAGA
CGAGTTACGTCAGTTGGACATCTATAACATGACTCCAATGGAAGTGATGTTGGCTGTGGCAGAGATGAAGAAGAAACTTT
AA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (255-546)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	75.967	100	0.76
mutS	Pseudomonas stutzeri strain ATCC 17587	36.616	100	0.37