Detailed information NTG0470896

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: HBNCFIEN_RS03620
• Genome accession: NZ_CP059576
• Coordinates: 863693..864766 (+)
• Length: 357 a.a.
• NCBI ID: WP_182392725.1
• Uniprot ID: A0A7G4RDT8
• Organism: Legionella sp. PC997
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 858693..869766

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HBNCFIEN_RS03595 (HBNCFIEN_00724)	-	859003..859758 (-)	756	WP_182392720.1	CPBP family intramembrane metalloprotease	-
HBNCFIEN_RS03600 (HBNCFIEN_00725)	rsmB	859755..861041 (-)	1287	WP_182392721.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
HBNCFIEN_RS03605 (HBNCFIEN_00726)	fmt	861041..861982 (-)	942	WP_182392722.1	methionyl-tRNA formyltransferase	-
HBNCFIEN_RS03610 (HBNCFIEN_00727)	def	862058..862567 (-)	510	WP_182392723.1	peptide deformylase	-
HBNCFIEN_RS03615 (HBNCFIEN_00728)	-	862659..863696 (+)	1038	WP_182392724.1	LysM peptidoglycan-binding domain-containing protein	-
HBNCFIEN_RS03620 (HBNCFIEN_00729)	dprA	863693..864766 (+)	1074	WP_182392725.1	DNA-processing protein DprA	Machinery gene
HBNCFIEN_RS03625 (HBNCFIEN_00730)	-	864770..865201 (+)	432	WP_182392726.1	DUF494 family protein	-
HBNCFIEN_RS03630 (HBNCFIEN_00731)	topA	865332..867626 (+)	2295	WP_182392727.1	type I DNA topoisomerase	-
HBNCFIEN_RS03635 (HBNCFIEN_00732)	-	867679..867948 (-)	270	WP_182392728.1	hypothetical protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 38827.95 Da
• Isoelectric Point: 6.7146

>NTDB_id=470896 HBNCFIEN_RS03620 WP_182392725.1 863693..864766(+) (dprA) [Legionella sp. PC997]
MNNLPYYLALNRMERVGPRTVIKLQNRWPELQQMFQLSVTELEQAGLPGALAQAIAQFDMNVIEEDLRWLHAADDHHLLT
WESPEYPSLLKEITDPPIVLYAKGQLACLKQLKLAIVGSRNPTVTGSENARHFAKAIASHGVAIVSGLALGIDAQAHQGC
LEAEGQTIAVLGTGIDRIYPHRHQALSQKITQNGLLISEFPLKSPPIAGHFPRRNRIISGLSLCILVVESAIKSGSLITA
RMALEQNRDVLAIPGSIHNPLARGCHYLLQQGAKLVTSVVDVLEELGIVSEPQTADKAILPLASGNKNLVKFIGFEMTTV
DQIILRSGCTVEQVTSELAELELNGAVVSVPGGYMRC

Nucleotide

• Length: 1074 bp

>NTDB_id=470896 HBNCFIEN_RS03620 WP_182392725.1 863693..864766(+) (dprA) [Legionella sp. PC997]
ATGAATAATTTACCCTATTATCTTGCATTAAACCGAATGGAACGAGTGGGTCCCCGCACCGTTATCAAACTACAAAATCG
TTGGCCTGAGTTGCAGCAAATGTTTCAACTCTCCGTCACTGAACTCGAACAAGCGGGCTTACCGGGGGCTTTGGCGCAGG
CTATAGCTCAATTCGATATGAATGTGATTGAAGAAGATTTGCGTTGGTTGCATGCAGCAGACGATCATCATCTTCTTACC
TGGGAGTCTCCTGAATATCCTTCTTTACTAAAGGAAATTACGGATCCTCCCATTGTTTTATATGCTAAAGGCCAGCTTGC
CTGTTTAAAGCAGCTAAAACTTGCAATAGTAGGAAGTCGTAATCCGACAGTAACTGGAAGTGAAAACGCACGACACTTTG
CAAAGGCAATCGCTTCGCATGGAGTGGCTATTGTGAGTGGTTTGGCTCTAGGTATTGATGCGCAGGCTCATCAAGGGTGT
TTAGAGGCCGAAGGGCAAACAATAGCCGTATTAGGGACAGGAATTGATCGAATTTATCCCCATCGGCATCAGGCATTATC
ACAAAAAATTACTCAAAATGGCCTATTAATAAGCGAATTTCCTTTGAAAAGTCCTCCTATCGCTGGACATTTCCCCCGAA
GAAATCGTATAATAAGTGGTTTATCATTGTGCATTTTGGTTGTTGAGTCGGCAATCAAGAGTGGATCACTAATCACGGCA
CGAATGGCCTTAGAACAAAATCGAGATGTTTTAGCGATCCCGGGCTCCATTCACAATCCTCTGGCTCGAGGGTGTCATTA
CCTGTTGCAGCAAGGAGCCAAATTAGTTACTTCAGTTGTGGATGTTCTTGAGGAGTTAGGAATTGTTTCGGAACCGCAAA
CAGCTGATAAAGCTATTTTACCTCTTGCCAGCGGGAATAAAAACCTAGTAAAGTTCATTGGCTTTGAAATGACTACAGTG
GATCAGATCATTTTACGTAGCGGATGCACCGTTGAGCAAGTCACAAGTGAACTTGCAGAATTAGAATTAAATGGGGCTGT
TGTATCTGTGCCCGGTGGCTATATGAGGTGTTAG

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (297-353)

• DNA recombination-mediator protein A (DNA_processg_A) (74-277)

3D structure

• AlphaFold DB: A0A7G4RDT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Legionella pneumophila strain ERS1305867	73.109	100	0.731
dprA	Vibrio campbellii strain DS40M4	43.716	100	0.448
dprA	Vibrio cholerae strain A1552	43.243	100	0.448
dprA	Glaesserella parasuis strain SC1401	38.83	100	0.409