Detailed information NTG0047026

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: HPSNT_RS01815
• Genome accession: NC_017376
• Coordinates: 373055..373855 (+)
• Length: 266 a.a.
• NCBI ID: WP_000841123.1
• Uniprot ID: G2MBH5
• Organism: Helicobacter pylori SNT49
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 368055..378855

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPSNT_RS01780 (HPSNT_01815)	pseH	368546..369088 (+)	543	WP_000742665.1	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase	-
HPSNT_RS01785 (HPSNT_01820)	-	369021..369959 (-)	939	WP_000833979.1	tetraacyldisaccharide 4'-kinase	-
HPSNT_RS01790 (HPSNT_01825)	-	369956..370738 (-)	783	WP_001168319.1	NAD+ synthase	-
HPSNT_RS01800 (HPSNT_01830)	ilvC	370996..371988 (+)	993	WP_001207574.1	ketol-acid reductoisomerase	-
HPSNT_RS01805 (HPSNT_01835)	minD	372012..372818 (+)	807	WP_001019089.1	septum site-determining protein MinD	-
HPSNT_RS01810 (HPSNT_01840)	minE	372815..373048 (+)	234	WP_000051425.1	cell division topological specificity factor MinE	-
HPSNT_RS01815 (HPSNT_01845)	dprA	373055..373855 (+)	801	WP_000841123.1	DNA-processing protein DprA	Machinery gene
HPSNT_RS01820 (HPSNT_01850)	dprB	373852..374256 (+)	405	WP_000599261.1	Holliday junction resolvase RuvX	Machinery gene
HPSNT_RS08535 (HPSNT_01855)	-	374389..374541 (+)	153	WP_014536683.1	tetratricopeptide repeat protein	-
HPSNT_RS01830 (HPSNT_01860)	-	374664..374969 (+)	306	WP_000699930.1	hypothetical protein	-
HPSNT_RS01835 (HPSNT_01865)	-	374953..375519 (+)	567	WP_000032372.1	hypothetical protein	-
HPSNT_RS01840 (HPSNT_01870)	-	375603..376484 (-)	882	WP_001117119.1	RluA family pseudouridine synthase	-
HPSNT_RS01845 (HPSNT_01875)	recJ	376484..378034 (-)	1551	WP_000810807.1	single-stranded-DNA-specific exonuclease RecJ	-

Sequence

Protein

• Length: 266 a.a.
• Molecular weight: 29830.76 Da
• Isoelectric Point: 8.5925

>NTDB_id=47026 HPSNT_RS01815 WP_000841123.1 373055..373855(+) (dprA) [Helicobacter pylori SNT49]
MKSNFQYSALENIPKVFDILKDPPKKLYCVGDTKLLEAPLKVAIIGTRRPTPYSKQHTITLARELAKNGAVIVSGGALGV
DIIAQENALPKTIMLSPCSLDFIYPTNNHKVIQEIAQNGLILSEYEKDFMPVKGSFLARNRLVIALSDAVIIPQADLKSG
SMSSARLAQKYQKPLFVLPQRLNESDGTNELLEKGQAQGIFNIQNFINTLLKDHHLKEMPEMKDEFLEYCAKNPSYEEAY
LKFGDKLLEYELLGKIKRINHIVVLA

Nucleotide

• Length: 801 bp

>NTDB_id=47026 HPSNT_RS01815 WP_000841123.1 373055..373855(+) (dprA) [Helicobacter pylori SNT49]
ATGAAAAGTAATTTCCAATACAGCGCACTAGAAAATATCCCTAAAGTCTTTGACATTCTCAAAGACCCCCCTAAAAAGCT
CTATTGTGTGGGCGATACCAAGCTTTTAGAAGCGCCTTTAAAAGTGGCTATCATAGGCACAAGAAGACCCACCCCTTACA
GCAAGCAACACACGATCACTCTAGCCAGAGAGCTTGCTAAAAATGGCGCGGTTATTGTGAGTGGGGGAGCGTTAGGCGTG
GATATTATCGCTCAAGAAAACGCCTTACCAAAAACGATCATGCTTTCGCCTTGCAGTCTGGATTTCATCTATCCTACGAA
CAACCATAAAGTGATCCAAGAAATCGCGCAAAACGGCTTGATTTTAAGCGAATATGAAAAGGATTTCATGCCCGTTAAAG
GCTCTTTTTTAGCCAGAAACCGCCTGGTGATCGCTTTAAGCGATGCGGTGATTATCCCCCAAGCGGATTTAAAAAGCGGC
TCTATGAGCAGCGCGAGATTAGCTCAAAAATACCAAAAACCCTTATTTGTTTTACCCCAGCGCTTGAATGAGAGCGATGG
CACTAATGAGCTTTTAGAAAAAGGGCAGGCTCAAGGGATATTTAATATTCAAAATTTTATAAACACCCTTTTAAAAGACC
ACCATTTAAAAGAAATGCCTGAAATGAAAGATGAATTTTTAGAATATTGCGCGAAAAACCCTAGCTATGAAGAGGCGTAT
CTCAAATTTGGGGATAAGCTTTTAGAATATGAGCTGTTGGGTAAGATTAAACGCATCAATCATATCGTGGTGTTAGCGTG
A

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (12-197)

3D structure

• AlphaFold DB: G2MBH5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Helicobacter pylori 26695	96.617	100	0.966
dprA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	48.673	84.962	0.414