Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   HMPREF0462_RS01910 Genome accession   NC_017375
Coordinates   378755..379555 (+) Length   266 a.a.
NCBI ID   WP_000841137.1    Uniprot ID   F4D4S1
Organism   Helicobacter pylori 83     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 373755..384555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0462_RS01875 (HMPREF0462_0385) pseH 374255..374797 (+) 543 WP_000742586.1 UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase -
  HMPREF0462_RS01880 (HMPREF0462_0386) - 374730..375668 (-) 939 WP_000833951.1 tetraacyldisaccharide 4'-kinase -
  HMPREF0462_RS01885 (HMPREF0462_0387) - 375665..376447 (-) 783 WP_001168210.1 NAD+ synthase -
  HMPREF0462_RS01895 (HMPREF0462_0388) ilvC 376696..377688 (+) 993 WP_001207774.1 ketol-acid reductoisomerase -
  HMPREF0462_RS01900 (HMPREF0462_0389) minD 377707..378513 (+) 807 WP_001019097.1 septum site-determining protein MinD -
  HMPREF0462_RS01905 (HMPREF0462_0390) minE 378510..378743 (+) 234 WP_000051409.1 cell division topological specificity factor MinE -
  HMPREF0462_RS01910 (HMPREF0462_0391) dprA 378755..379555 (+) 801 WP_000841137.1 DNA-processing protein DprA Machinery gene
  HMPREF0462_RS01915 (HMPREF0462_0392) dprB 379552..379956 (+) 405 WP_000599231.1 Holliday junction resolvase RuvX Machinery gene
  HMPREF0462_RS01920 (HMPREF0462_0393) - 380087..380560 (+) 474 WP_014536432.1 tetratricopeptide repeat protein -
  HMPREF0462_RS01925 (HMPREF0462_0394) - 380748..381086 (+) 339 WP_000699916.1 hypothetical protein -
  HMPREF0462_RS01930 (HMPREF0462_0395) - 381070..381630 (+) 561 WP_000037141.1 hypothetical protein -
  HMPREF0462_RS08545 (HMPREF0462_0396) - 381641..382141 (+) 501 WP_014536433.1 glycoside hydrolase family protein -
  HMPREF0462_RS08680 (HMPREF0462_0397) - 382161..382322 (+) 162 WP_014536434.1 lysozyme -
  HMPREF0462_RS08550 (HMPREF0462_0398) - 382380..382574 (+) 195 WP_001267764.1 hypothetical protein -
  HMPREF0462_RS01945 (HMPREF0462_0399) - 382652..383038 (+) 387 WP_000397547.1 DUF1294 domain-containing protein -
  HMPREF0462_RS01950 - 383038..383823 (+) 786 WP_000488077.1 hypothetical protein -

Sequence

Protein


Download         Length: 266 a.a.        Molecular weight: 29729.64 Da        Isoelectric Point: 8.2376

>NTDB_id=47002 HMPREF0462_RS01910 WP_000841137.1 378755..379555(+) (dprA) [Helicobacter pylori 83]
MKSNFQYSVLENIPKAFDILKDPPKKLYCAGDIKLLDAPLKVAIIGTRRPTPYSKQHTITLARELAKNGAVIVSGGALGV
DIIAQENALPKTIMLSPCSLDLIYPTNNHKVIQEIAQNGLILSEYEKDFMPVKGSFLARNRLVIALSDAVIIPQADLKSG
SMSSARLAQKYQKPLFVLPQHLNESDGTNELLEKGQAQGIFNIQNFINTLLKDHHLKEMPEIKDEFLEYCAKNPSYEEAY
LKFGDKLLEYELLGKIKRINHIVVLA

Nucleotide


Download         Length: 801 bp        

>NTDB_id=47002 HMPREF0462_RS01910 WP_000841137.1 378755..379555(+) (dprA) [Helicobacter pylori 83]
ATGAAAAGCAACTTCCAATACAGCGTGCTAGAGAATATCCCTAAAGCCTTTGACATTCTCAAAGACCCCCCTAAAAAGCT
CTATTGTGCGGGTGATATAAAGCTTTTAGATGCGCCTTTAAAAGTGGCTATCATCGGCACAAGAAGACCCACCCCTTATA
GCAAGCAACACACCATCACTCTAGCCAGAGAGCTTGCTAAAAATGGCGCGGTTATTGTGAGCGGAGGAGCGTTAGGCGTG
GATATTATCGCTCAAGAAAACGCCTTACCAAAAACCATCATGCTTTCGCCTTGCAGTTTGGATTTAATCTATCCCACAAA
CAACCATAAAGTGATCCAAGAAATCGCGCAAAACGGCTTGATTTTAAGCGAATATGAAAAGGATTTTATGCCCGTTAAAG
GCTCTTTTTTAGCGAGAAACCGCCTAGTGATCGCTTTAAGCGATGCGGTAATTATCCCCCAAGCGGATTTAAAAAGCGGC
TCTATGAGCAGCGCTAGATTAGCCCAAAAGTATCAAAAACCCTTATTTGTTTTGCCCCAGCACCTGAATGAGAGCGATGG
CACTAATGAGCTTTTAGAAAAAGGGCAGGCTCAAGGGATATTTAATATTCAAAATTTTATAAACACCCTTTTAAAAGACC
ACCATTTAAAAGAAATGCCTGAAATCAAAGATGAATTTTTAGAATATTGCGCCAAAAACCCTAGCTATGAAGAGGCGTAT
CTCAAATTTGGGGACAAGCTTTTAGAATACGAGCTGTTGGGTAAGATTAAACGCATCAATCATATCGTGGTGTTAGCGTG
A

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(13-197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F4D4S1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Helicobacter pylori 26695

95.489

100

0.955
  dprA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

48.23

84.962

0.41

Multiple sequence alignment