Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGE   Type   Machinery gene
Locus tag   M1GAS476_RS00600 Genome accession   NC_020540
Coordinates   98674..98958 (+) Length   94 a.a.
NCBI ID   WP_002987779.1    Uniprot ID   A0A0H2USY2
Organism   Streptococcus pyogenes M1 476     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 93674..103958
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M1GAS476_RS00575 (M1GAS476_0121) - 95620..95985 (+) 366 WP_002986560.1 DUF1033 family protein -
  M1GAS476_RS00580 (M1GAS476_0122) comGA 96078..97016 (+) 939 WP_010921798.1 competence type IV pilus ATPase ComGA Machinery gene
  M1GAS476_RS00585 (M1GAS476_0123) comGB 96952..97986 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  M1GAS476_RS00590 (M1GAS476_0125) comGC 97988..98314 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  M1GAS476_RS00595 (M1GAS476_0126) comGD 98289..98717 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  M1GAS476_RS00600 comGE 98674..98958 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  M1GAS476_RS00605 (M1GAS476_0128) comGF 98951..99385 (+) 435 WP_010921800.1 competence type IV pilus minor pilin ComGF Machinery gene
  M1GAS476_RS00610 (M1GAS476_0129) comGG 99369..99695 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  M1GAS476_RS00615 (M1GAS476_0130) comGH 99793..100746 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  M1GAS476_RS00620 (M1GAS476_0131) - 100805..102001 (+) 1197 WP_010921803.1 acetate kinase -
  M1GAS476_RS00625 (M1GAS476_0132) - 102188..102496 (+) 309 WP_010921804.1 hypothetical protein -
  M1GAS476_RS00630 (M1GAS476_0133) proC 102579..103349 (-) 771 WP_010921805.1 pyrroline-5-carboxylate reductase -

Sequence


Protein


Download         Length: 94 a.a.        Molecular weight: 10672.62 Da        Isoelectric Point: 8.9043

>NTDB_id=47003 M1GAS476_RS00600 WP_002987779.1 98674..98958(+) (comGE) [Streptococcus pyogenes M1 476]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=47003 M1GAS476_RS00600 WP_002987779.1 98674..98958(+) (comGE) [Streptococcus pyogenes M1 476]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0H2USY2

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383


Multiple sequence alignment