Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   H1R75_RS02765 Genome accession   NZ_CP059471
Coordinates   508017..509315 (+) Length   432 a.a.
NCBI ID   WP_182001611.1    Uniprot ID   -
Organism   Streptococcus equinus strain MDC1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 503017..514315
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1R75_RS02740 (H1R75_02740) - 503711..504355 (+) 645 WP_024344653.1 response regulator transcription factor -
  H1R75_RS02745 (H1R75_02745) - 504479..505879 (+) 1401 WP_182001610.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  H1R75_RS02750 (H1R75_02750) - 505879..506235 (+) 357 WP_027968108.1 S1 RNA-binding domain-containing protein -
  H1R75_RS02755 (H1R75_02755) cysK 506309..507238 (-) 930 WP_033152045.1 cysteine synthase A -
  H1R75_RS02760 (H1R75_02760) - 507336..507962 (-) 627 WP_157339043.1 YigZ family protein -
  H1R75_RS02765 (H1R75_02765) comFA/cflA 508017..509315 (+) 1299 WP_182001611.1 DEAD/DEAH box helicase Machinery gene
  H1R75_RS02770 (H1R75_02770) - 509315..509980 (+) 666 WP_182001612.1 ComF family protein -
  H1R75_RS02775 (H1R75_02775) hpf 510057..510605 (+) 549 WP_024344660.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49026.20 Da        Isoelectric Point: 9.4749

>NTDB_id=469816 H1R75_RS02765 WP_182001611.1 508017..509315(+) (comFA/cflA) [Streptococcus equinus strain MDC1]
MEDKNDYYGRIFVESQLSDELKEEAEKLPSMVKRKGDLTCNRCGSIVLPDNILQTGQTYCRECLVFGRSISDSYLYYFPQ
KSFPKNNSLNWQGQLTPYQNEVSEGMLSGIAEKKDLLVHAVTGAGKTEMIYHSVAKIIDDGGCVCIASPRIDVCLELYKR
MSRDFSCPITLLHGEAEPYKRAPLIIATTHQLLKFYQAFDLLIIDEVDAFPFVDNKMLYYAVNQSLKKDGVKIFLTATST
DELDKKVRKGDLKKLHLARRFHANPLVVPKMLWLSGVLKSMKKGKIPKKLNLLLKNQRKAGYPLLIFFPNIEQGKRFSMV
LQEKFPTEKIGFVSSQTEDRLELVEKFRKNEITILVSTTILERGVTFPCVDVFVVLANHKLYTKSALVQISGRVGRAAER
PTGELLFLHDGATKSMQQAIKEIKEMNKKGGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=469816 H1R75_RS02765 WP_182001611.1 508017..509315(+) (comFA/cflA) [Streptococcus equinus strain MDC1]
ATGGAAGATAAAAATGACTATTATGGAAGAATTTTTGTTGAGTCTCAATTGTCTGATGAGTTAAAAGAAGAAGCTGAAAA
ACTTCCTTCTATGGTAAAAAGAAAAGGCGATCTTACGTGTAACCGCTGCGGAAGCATTGTTTTACCAGATAATATTTTAC
AAACTGGTCAGACTTACTGCAGAGAATGTCTAGTTTTTGGTCGTAGCATCAGTGATTCTTATCTATATTACTTTCCGCAA
AAAAGTTTTCCAAAAAATAATTCTCTAAACTGGCAAGGGCAACTTACCCCTTATCAAAATGAAGTGTCAGAAGGTATGTT
GTCAGGAATTGCTGAAAAGAAAGATTTATTAGTTCATGCTGTGACAGGAGCTGGTAAGACAGAGATGATTTATCACTCAG
TAGCAAAAATAATCGATGACGGTGGTTGTGTTTGTATTGCTAGCCCACGAATTGATGTTTGTTTAGAGCTTTATAAACGT
ATGTCTCGTGATTTTTCATGTCCGATTACTTTATTACACGGGGAAGCTGAGCCTTACAAACGAGCACCGCTCATTATTGC
AACAACTCATCAACTTTTAAAATTCTACCAAGCATTTGATTTATTAATTATTGATGAAGTTGATGCTTTTCCATTTGTTG
ACAATAAAATGCTGTATTACGCAGTAAATCAATCTTTAAAAAAAGATGGTGTCAAGATATTTTTAACAGCCACATCGACA
GATGAATTAGATAAAAAAGTTCGAAAAGGCGACTTAAAAAAATTGCATTTAGCCAGACGTTTTCACGCCAATCCTTTGGT
TGTTCCTAAAATGCTCTGGCTTAGTGGGGTGTTAAAGTCAATGAAAAAAGGAAAAATACCTAAAAAATTGAACTTGCTGC
TTAAAAATCAAAGAAAAGCAGGATATCCCTTACTAATCTTTTTTCCAAATATAGAGCAGGGAAAAAGATTTTCGATGGTT
CTGCAAGAAAAATTTCCTACTGAGAAGATTGGTTTTGTGTCAAGTCAGACCGAAGATAGGCTCGAATTAGTTGAAAAATT
TAGAAAGAACGAAATAACAATTTTAGTCAGCACAACCATCTTAGAACGTGGAGTCACGTTTCCTTGTGTTGACGTATTTG
TTGTATTAGCAAATCACAAATTATACACTAAAAGTGCCTTGGTTCAAATTTCTGGGCGAGTCGGTAGAGCTGCTGAACGA
CCAACAGGAGAATTATTATTTTTGCACGATGGCGCTACAAAATCTATGCAACAAGCGATTAAAGAAATAAAGGAAATGAA
CAAGAAAGGAGGATTTTGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-397)

DEAD/DEAH box helicase (DEAD)

(96-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

63.466

98.843

0.627
  comFA/cflA Streptococcus pneumoniae D39

63.466

98.843

0.627
  comFA/cflA Streptococcus pneumoniae R6

63.466

98.843

0.627
  comFA/cflA Streptococcus pneumoniae TIGR4

63.466

98.843

0.627
  comFA/cflA Streptococcus mitis NCTC 12261

61.806

100

0.618
  comFA/cflA Streptococcus mitis SK321

61.343

100

0.613
  comFA Lactococcus lactis subsp. cremoris KW2

48.815

97.685

0.477
  comFA Latilactobacillus sakei subsp. sakei 23K

37.011

100

0.373
  comFA Bacillus subtilis subsp. subtilis str. 168

36.054

100

0.368