Detailed information NTG0046957

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: HPIN_RS01520
• Genome accession: NC_017372
• Coordinates: 304805..305605 (+)
• Length: 266 a.a.
• NCBI ID: WP_000840077.1
• Uniprot ID: E8QEQ5
• Organism: Helicobacter pylori India7
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 299805..310605

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPIN_RS01485 (HPIN_01495)	pseH	300297..300839 (+)	543	WP_000742681.1	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase	-
HPIN_RS01490 (HPIN_01500)	-	300772..301710 (-)	939	WP_000833929.1	tetraacyldisaccharide 4'-kinase	-
HPIN_RS01495 (HPIN_01505)	-	301707..302489 (-)	783	WP_001168226.1	NAD+ synthase	-
HPIN_RS01505 (HPIN_01510)	ilvC	302738..303730 (+)	993	WP_001207740.1	ketol-acid reductoisomerase	-
HPIN_RS01510 (HPIN_01515)	minD	303755..304561 (+)	807	WP_001019061.1	septum site-determining protein MinD	-
HPIN_RS01515 (HPIN_01520)	minE	304558..304791 (+)	234	WP_000051424.1	cell division topological specificity factor MinE	-
HPIN_RS01520 (HPIN_01525)	dprA	304805..305605 (+)	801	WP_000840077.1	DNA-processing protein DprA	Machinery gene
HPIN_RS01525 (HPIN_01530)	dprB	305602..306006 (+)	405	WP_000599262.1	Holliday junction resolvase RuvX	Machinery gene
HPIN_RS08880	-	306141..306341 (+)	201	WP_412081015.1	sel1 repeat family protein	-
HPIN_RS08885	-	306409..306720 (+)	312	WP_412081016.1	tetratricopeptide repeat protein	-
HPIN_RS01535 (HPIN_01550)	-	306907..307212 (+)	306	WP_000699929.1	hypothetical protein	-
HPIN_RS01540 (HPIN_01555)	-	307196..307762 (+)	567	WP_000032371.1	hypothetical protein	-
HPIN_RS01545 (HPIN_01560)	-	307849..308730 (-)	882	WP_001117120.1	RluA family pseudouridine synthase	-
HPIN_RS01550 (HPIN_01565)	recJ	308730..310280 (-)	1551	WP_000810740.1	single-stranded-DNA-specific exonuclease RecJ	-

Sequence

Protein

• Length: 266 a.a.
• Molecular weight: 29797.73 Da
• Isoelectric Point: 8.5799

>NTDB_id=46957 HPIN_RS01520 WP_000840077.1 304805..305605(+) (dprA) [Helicobacter pylori India7]
MKSNFPYSALENIPKAFDILKDPPKKLYCVGDTKLLEAPLKVAIIGTRRPTPYSKQHTITLARELAKNGAVIVSGGALGV
DIIAQENALPKTIMLSPCSLDFVYPTNNHKVIQEIAQNGLILSEYEKDFMPIKGSFLARNRLVIALSDAVIIPQADLKSG
SMSSARLAQKYQKPLFVLPQRLNESDGTNELLEKGQAQGIFNIQNFINTLLKDYHLKEMPEMKDEFLEYCAKNPSYEEAY
LKFGDKLLEYELLGKIKRINHIVVLA

Nucleotide

• Length: 801 bp

>NTDB_id=46957 HPIN_RS01520 WP_000840077.1 304805..305605(+) (dprA) [Helicobacter pylori India7]
ATGAAAAGCAACTTCCCATACAGCGCGCTAGAAAATATCCCTAAAGCCTTTGATATTCTCAAAGACCCCCCTAAAAAGCT
CTATTGTGTGGGCGATACCAAGCTTTTAGAAGCGCCTTTAAAAGTGGCTATCATCGGCACAAGAAGACCCACCCCTTATA
GCAAGCAACACACCATCACTCTAGCCAGAGAGCTTGCTAAAAATGGTGCGGTTATTGTGAGCGGAGGAGCGTTAGGCGTG
GATATCATCGCTCAAGAAAACGCCTTACCAAAAACCATCATGCTTTCGCCTTGCAGTTTGGATTTTGTCTATCCTACGAA
CAACCATAAAGTGATCCAAGAAATCGCGCAAAACGGCTTGATTTTAAGCGAATATGAAAAAGATTTTATGCCTATTAAAG
GCTCTTTTTTAGCCAGAAACCGCCTGGTGATCGCTTTAAGCGATGCGGTGATTATCCCCCAAGCGGATTTAAAAAGCGGC
TCTATGAGCAGCGCGAGATTAGCTCAAAAATACCAAAAGCCCTTATTTGTTTTGCCTCAGCGCTTGAATGAGAGCGATGG
CACTAATGAGCTTTTAGAAAAAGGGCAGGCTCAAGGGATATTTAATATTCAAAATTTTATAAACACCCTTTTAAAAGACT
ACCATTTAAAAGAAATGCCTGAAATGAAAGATGAATTTTTAGAATATTGCGCCAAAAACCCTAGCTATGAAGAAGCGTAT
CTCAAATTTGGGGATAAGCTTTTAGAATACGAGCTGTTGGGTAAGATTAAACGCATCAATCATATCGTGGTGTTAGCGTG
A

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (12-197)

3D structure

• AlphaFold DB: E8QEQ5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Helicobacter pylori 26695	96.992	100	0.97
dprA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	48.23	84.962	0.41