Detailed information NTG0046954

Bioinformatically predicted

Overview

• Name: comB10
• Type: Machinery gene
• Locus tag: HPIN_RS00215
• Genome accession: NC_017372
• Coordinates: 39008..40144 (+)
• Length: 378 a.a.
• NCBI ID: WP_001045887.1
• Uniprot ID: E8QD99
• Organism: Helicobacter pylori India7
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 34008..45144

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPIN_RS00180 (HPIN_00155)	panD	34472..34825 (+)	354	WP_000142217.1	aspartate 1-decarboxylase	-
HPIN_RS00185 (HPIN_00160)	-	34828..35130 (+)	303	WP_000347927.1	YbaB/EbfC family nucleoid-associated protein	-
HPIN_RS00190 (HPIN_00165)	-	35130..36125 (+)	996	WP_000902470.1	PDZ domain-containing protein	-
HPIN_RS00195 (HPIN_00170)	comB6	36133..37188 (+)	1056	WP_000679752.1	P-type conjugative transfer protein TrbL	Machinery gene
HPIN_RS08575	comB7	37224..37316 (+)	93	WP_000524813.1	hypothetical protein	Machinery gene
HPIN_RS00205 (HPIN_00175)	comB8	37313..38050 (+)	738	WP_000660571.1	type IV secretion system protein	Machinery gene
HPIN_RS00210 (HPIN_00180)	comB9	38050..39015 (+)	966	WP_014536042.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
HPIN_RS00215 (HPIN_00185)	comB10	39008..40144 (+)	1137	WP_001045887.1	DNA type IV secretion system protein ComB10	Machinery gene
HPIN_RS00220 (HPIN_00190)	-	40214..41632 (+)	1419	WP_000694843.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-
HPIN_RS00225 (HPIN_00195)	gmd	41642..42787 (+)	1146	WP_000412696.1	GDP-mannose 4,6-dehydratase	-
HPIN_RS00230 (HPIN_00200)	-	42780..43712 (+)	933	WP_001002912.1	GDP-L-fucose synthase family protein	-
HPIN_RS08860	-	43740..43957 (-)	218	Protein_41	anthranilate synthase component I	-

Sequence

Protein

• Length: 378 a.a.
• Molecular weight: 42079.61 Da
• Isoelectric Point: 9.9312

>NTDB_id=46954 HPIN_RS00215 WP_001045887.1 39008..40144(+) (comB10) [Helicobacter pylori India7]
MNKWLKGAVVFVGGFATITTISLVYHQKPKAPLNNQPSLLNDDEVKYPLQDYTFTQNPQPTNTESSKDATIKALQEQLKA
ALKALNSKEMNHSKEETFTNPPIDLKANTTPPKKDFSPKQLDLLAARITPFKQSPKNYEENLIFPMDNPKGIDGFTNLKE
KDIATNENKLLRTITADKMIPAFLITPISSQIAGKVIAQVESDIFAHMGKAVLIPKGSKVIGYYSNNNKMGEYRLDIVWS
RIITPHGINIMLTNAKGADIKGYNGLVGELIERNFQRYGVPLLLSTLTNGLLIGITSALNNRGNKEGATNFFGDYLLMQL
MRQSGMGINQVVNQILRDKSKIAPIVVVREGSRVFISPNTDIFFPIPRENEVIAEFLK

Nucleotide

• Length: 1137 bp

>NTDB_id=46954 HPIN_RS00215 WP_001045887.1 39008..40144(+) (comB10) [Helicobacter pylori India7]
ATGAATAAGTGGCTTAAGGGGGCGGTTGTTTTTGTAGGGGGTTTTGCAACGATTACAACCATTTCTTTAGTCTATCATCA
AAAGCCAAAAGCCCCCTTAAATAACCAGCCTAGCCTTTTAAATGACGATGAGGTGAAATACCCCTTACAAGACTACACCT
TCACTCAAAACCCACAGCCAACCAACACGGAAAGCTCCAAAGACGCTACTATTAAAGCCTTACAAGAACAGCTAAAAGCC
GCTTTAAAAGCCCTAAACTCCAAAGAAATGAACCACTCTAAAGAAGAAACTTTTACTAACCCTCCCATAGATTTAAAAGC
AAACACAACCCCCCCTAAAAAAGATTTTTCTCCAAAGCAATTAGATTTATTAGCCGCTCGCATCACCCCTTTCAAACAAA
GCCCTAAAAATTACGAAGAAAACCTGATTTTCCCCATGGATAACCCTAAAGGGATCGATGGTTTCACTAACCTTAAAGAA
AAAGACATTGCTACCAATGAAAACAAGCTTTTACGCACCATTACAGCCGATAAGATGATACCCGCCTTTCTCATCACGCC
CATTTCTAGTCAGATCGCTGGTAAAGTGATTGCGCAAGTGGAGAGCGATATTTTCGCTCACATGGGCAAGGCCGTCTTAA
TCCCCAAAGGCTCTAAAGTCATAGGCTATTACAGCAACAATAACAAAATGGGCGAATACCGCTTGGATATTGTATGGAGT
CGAATCATCACTCCCCATGGGATTAATATCATGCTCACTAACGCTAAGGGGGCGGACATTAAAGGCTATAACGGCTTGGT
GGGGGAATTGATTGAAAGGAATTTCCAACGCTATGGCGTGCCGTTACTGCTTTCTACTCTCACTAACGGCTTGTTGATTG
GGATCACTTCGGCTTTAAACAACAGAGGCAATAAAGAAGGAGCCACCAATTTCTTTGGGGATTATCTTTTAATGCAATTG
ATGAGGCAAAGCGGCATGGGGATCAATCAAGTGGTCAATCAAATTTTAAGAGACAAGAGCAAGATTGCTCCTATTGTGGT
GGTTAGAGAGGGAAGTAGGGTCTTCATTTCGCCCAATACTGACATCTTCTTTCCTATACCCAGAGAGAATGAAGTCATCG
CTGAGTTTTTGAAGTGA

Domains

Predicted by InterproScan.

• Bacterial conjugation TrbI-like protein (TrbI) (173-364)

3D structure

• AlphaFold DB: E8QD99

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB10	Helicobacter pylori P1	96.825	100	0.968