Detailed information NTG0046951

Bioinformatically predicted

Overview

• Name: comB6
• Type: Machinery gene
• Locus tag: HPIN_RS00195
• Genome accession: NC_017372
• Coordinates: 36133..37188 (+)
• Length: 351 a.a.
• NCBI ID: WP_000679752.1
• Uniprot ID: E8QD96
• Organism: Helicobacter pylori India7
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 31133..42188

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPIN_RS00165 (HPIN_00140)	-	31537..31950 (+)	414	WP_001023008.1	universal stress protein	-
HPIN_RS00170 (HPIN_00145)	-	31982..32257 (+)	276	WP_000784931.1	ATP-dependent Clp protease adaptor ClpS	-
HPIN_RS00175 (HPIN_00150)	-	32257..34482 (+)	2226	WP_001051479.1	AAA family ATPase	-
HPIN_RS00180 (HPIN_00155)	panD	34472..34825 (+)	354	WP_000142217.1	aspartate 1-decarboxylase	-
HPIN_RS00185 (HPIN_00160)	-	34828..35130 (+)	303	WP_000347927.1	YbaB/EbfC family nucleoid-associated protein	-
HPIN_RS00190 (HPIN_00165)	-	35130..36125 (+)	996	WP_000902470.1	PDZ domain-containing protein	-
HPIN_RS00195 (HPIN_00170)	comB6	36133..37188 (+)	1056	WP_000679752.1	P-type conjugative transfer protein TrbL	Machinery gene
HPIN_RS08575	comB7	37224..37316 (+)	93	WP_000524813.1	hypothetical protein	Machinery gene
HPIN_RS00205 (HPIN_00175)	comB8	37313..38050 (+)	738	WP_000660571.1	type IV secretion system protein	Machinery gene
HPIN_RS00210 (HPIN_00180)	comB9	38050..39015 (+)	966	WP_014536042.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
HPIN_RS00215 (HPIN_00185)	comB10	39008..40144 (+)	1137	WP_001045887.1	DNA type IV secretion system protein ComB10	Machinery gene
HPIN_RS00220 (HPIN_00190)	-	40214..41632 (+)	1419	WP_000694843.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 39905.87 Da
• Isoelectric Point: 9.0418

>NTDB_id=46951 HPIN_RS00195 WP_000679752.1 36133..37188(+) (comB6) [Helicobacter pylori India7]
MKHDAYEIILSWFITPLTAILGRFAEFFLYTLHAQLVFNSVVALAFMLFAYRSLKEQNFFSTSALTEALLFVGFFALFNY
ALKNPSRFYELFQNAIFIAPNMITQSLSQSLSNFSNHVLSLDFIFNHGFYALSFISDLSHNEMSVWLFLSILQGLFLSVL
FAIIILVYLEVHVWCSLGVLFLAFGFFKTWRSVVMACLKKCFALGFYKPFLLLVGFLNVSVTKALIDAHMQEKQDLSLLL
VVALFLCCVFIIGVPFFINALFRVQNSLKETYKLATNLSTNLSQNALNSLQYITTPPAPSSVSSSRSESVSKEKETHSPT
FKVETTQLDVKIPNFKQKKVKKDTINTKNEI

Nucleotide

• Length: 1056 bp

>NTDB_id=46951 HPIN_RS00195 WP_000679752.1 36133..37188(+) (comB6) [Helicobacter pylori India7]
ATGAAACATGACGCTTATGAGATTATCCTTTCTTGGTTTATCACGCCTCTCACGGCGATTTTAGGGCGTTTCGCTGAATT
TTTTCTCTACACCTTGCATGCGCAATTGGTGTTTAATAGCGTGGTCGCTTTGGCGTTCATGCTCTTTGCTTATAGGAGTT
TGAAAGAACAGAATTTCTTCAGCACCAGCGCGCTAACAGAAGCGTTATTGTTTGTGGGGTTTTTTGCGCTGTTTAACTAC
GCTTTGAAAAACCCTTCGCGCTTTTATGAATTGTTTCAAAACGCTATTTTTATTGCGCCTAACATGATCACACAAAGCCT
TTCTCAAAGCTTGAGTAACTTTTCTAACCACGTGCTTTCTTTAGATTTTATCTTTAACCATGGTTTTTATGCCCTTAGCT
TTATCAGCGATTTGAGCCATAATGAAATGTCTGTGTGGCTTTTTTTAAGCATTTTACAAGGGCTTTTTTTGAGCGTGCTG
TTTGCGATCATCATTTTAGTGTATTTAGAAGTGCATGTGTGGTGCTCTTTAGGGGTGTTGTTTTTAGCGTTTGGGTTTTT
TAAAACCTGGAGGAGCGTTGTAATGGCATGCCTAAAAAAATGCTTCGCTCTTGGGTTTTACAAGCCTTTTTTGTTGTTGG
TGGGGTTTTTGAATGTGTCGGTTACTAAGGCTTTAATAGACGCTCACATGCAAGAAAAACAAGACTTAAGCCTTTTGTTG
GTGGTAGCGTTATTTTTGTGTTGCGTTTTTATCATAGGCGTGCCTTTTTTCATCAACGCTTTGTTTAGGGTGCAAAACAG
CCTTAAAGAAACTTACAAACTCGCCACCAATTTGAGCACTAATCTCAGCCAAAACGCTCTCAATTCCTTACAATACATCA
CGACCCCACCCGCTCCCTCTAGCGTTTCTTCTTCTAGGAGTGAAAGCGTCTCTAAAGAAAAAGAAACGCATTCCCCCACA
TTTAAGGTAGAAACCACTCAATTAGATGTAAAAATCCCAAATTTCAAGCAAAAAAAGGTTAAAAAGGATACAATAAATAC
AAAAAATGAAATTTAA

Domains

Predicted by InterproScan.

• TrbL/VirB6 plasmid conjugal transfer protein (TrbL) (44-254)

3D structure

• AlphaFold DB: E8QD96

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB6	Helicobacter pylori 26695	96.011	100	0.96