Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JSQ88_RS02640 Genome accession   NZ_CP069621
Coordinates   510370..511026 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain PBP5     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 505370..516026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JSQ88_RS02610 (JSQ88_02590) yecA 506622..507287 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  JSQ88_RS02630 (JSQ88_02610) pgsA 507936..508484 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JSQ88_RS02635 (JSQ88_02615) uvrC 508541..510373 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JSQ88_RS02640 (JSQ88_02620) letA 510370..511026 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JSQ88_RS02645 (JSQ88_02625) yecU 511322..511498 (+) 177 WP_001304283.1 protein YecU -
  JSQ88_RS02650 (JSQ88_02630) yecF 511485..511709 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  JSQ88_RS02655 (JSQ88_02635) sdiA 511777..512499 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  JSQ88_RS02660 (JSQ88_02640) tcyN 512729..513481 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JSQ88_RS02665 (JSQ88_02645) tcyL 513478..514146 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  JSQ88_RS02670 (JSQ88_02650) dcyD 514161..515147 (-) 987 WP_001128236.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=468623 JSQ88_RS02640 WP_000611328.1 510370..511026(-) (letA) [Escherichia coli strain PBP5]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=468623 JSQ88_RS02640 WP_000611328.1 510370..511026(-) (letA) [Escherichia coli strain PBP5]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482