Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   I6J88_RS12000 Genome accession   NZ_CP069500
Coordinates   2392444..2393076 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain FDAARGOS_1258     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2387444..2398076
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J88_RS11975 (I6J88_11980) yheS 2387613..2389526 (+) 1914 WP_000634799.1 ABC transporter ATP-binding protein -
  I6J88_RS11980 (I6J88_11985) yheT 2389526..2390548 (+) 1023 WP_000057389.1 hydrolase -
  I6J88_RS11985 (I6J88_11990) yheU 2390542..2390760 (+) 219 WP_000907089.1 YheU family protein -
  I6J88_RS11990 (I6J88_11995) prkB 2390814..2391683 (+) 870 WP_001274680.1 phosphoribulokinase -
  I6J88_RS11995 (I6J88_12000) yhfA 2391738..2392142 (-) 405 WP_001148908.1 OsmC family protein -
  I6J88_RS12000 (I6J88_12005) crp 2392444..2393076 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  I6J88_RS12005 (I6J88_12010) yhfK 2393127..2395217 (+) 2091 WP_001298205.1 YccS/YhfK family putative transporter -
  I6J88_RS12010 (I6J88_12015) argD 2395284..2396504 (-) 1221 WP_000963803.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  I6J88_RS12015 (I6J88_12020) pabA 2396590..2397153 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  I6J88_RS12020 (I6J88_12025) fic 2397185..2397787 (-) 603 WP_001280662.1 putative adenosine monophosphate-protein transferase Fic -
  I6J88_RS12025 (I6J88_12030) yhfG 2397777..2397944 (-) 168 WP_000736859.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=467520 I6J88_RS12000 WP_000242755.1 2392444..2393076(+) (crp) [Escherichia coli strain FDAARGOS_1258]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=467520 I6J88_RS12000 WP_000242755.1 2392444..2393076(+) (crp) [Escherichia coli strain FDAARGOS_1258]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467