Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   I6J88_RS10260 Genome accession   NZ_CP069500
Coordinates   2061490..2062149 (+) Length   219 a.a.
NCBI ID   WP_204086159.1    Uniprot ID   -
Organism   Escherichia coli strain FDAARGOS_1258     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 2056490..2067149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J88_RS10245 (I6J88_10250) ygiS 2058695..2060302 (-) 1608 WP_001468194.1 ABC transporter substrate-binding protein -
  I6J88_RS10250 (I6J88_10255) ygiV 2060411..2060893 (-) 483 WP_000183493.1 GyrI-like domain-containing protein -
  I6J88_RS10255 (I6J88_10260) ygiW 2060946..2061338 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  I6J88_RS10260 (I6J88_10265) ciaR 2061490..2062149 (+) 660 WP_204086159.1 quorum sensing response regulator transcription factor QseB Regulator
  I6J88_RS10265 (I6J88_10270) qseC 2062146..2063495 (+) 1350 WP_000673388.1 quorum sensing histidine kinase QseC -
  I6J88_RS10270 (I6J88_10275) ygiZ 2063541..2063873 (-) 333 WP_000914696.1 DUF2645 family protein -
  I6J88_RS25280 - 2063880..2064590 (-) 711 WP_000834024.1 hypothetical protein -
  I6J88_RS25285 - 2064593..2065072 (-) 480 WP_000065329.1 Hcp family type VI secretion system effector -
  I6J88_RS10280 (I6J88_10285) mdaB 2065322..2065903 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  I6J88_RS10285 (I6J88_10290) ygiN 2065934..2066248 (+) 315 WP_000633738.1 putative quinol monooxygenase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24730.66 Da        Isoelectric Point: 7.4218

>NTDB_id=467514 I6J88_RS10260 WP_204086159.1 2061490..2062149(+) (ciaR) [Escherichia coli strain FDAARGOS_1258]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTRKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=467514 I6J88_RS10260 WP_204086159.1 2061490..2062149(+) (ciaR) [Escherichia coli strain FDAARGOS_1258]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAAGCGCTATATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCTGTATTGATCCTGACTGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGCAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACGCGGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTTCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.885

100

0.393
  ciaR Streptococcus pneumoniae D39

37.885

100

0.393
  ciaR Streptococcus pneumoniae R6

37.885

100

0.393
  ciaR Streptococcus pneumoniae TIGR4

37.885

100

0.393
  ciaR Streptococcus mutans UA159

35.426

100

0.361