Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   I6J91_RS08355 Genome accession   NZ_CP069441
Coordinates   1786771..1787430 (+) Length   219 a.a.
NCBI ID   WP_001221493.1    Uniprot ID   Q3YXL4
Organism   Escherichia coli strain FDAARGOS_1261     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1781771..1792430
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J91_RS08340 (I6J91_08340) ygiS 1783976..1785583 (-) 1608 WP_021529015.1 ABC transporter substrate-binding protein -
  I6J91_RS08345 (I6J91_08345) ygiV 1785692..1786174 (-) 483 WP_000183493.1 GyrI-like domain-containing protein -
  I6J91_RS08350 (I6J91_08350) ygiW 1786227..1786619 (-) 393 WP_021529016.1 OB fold stress tolerance protein YgiW -
  I6J91_RS08355 (I6J91_08355) ciaR 1786771..1787430 (+) 660 WP_001221493.1 quorum sensing response regulator transcription factor QseB Regulator
  I6J91_RS08360 (I6J91_08360) qseC 1787427..1788776 (+) 1350 WP_021529017.1 quorum sensing histidine kinase QseC -
  I6J91_RS08365 (I6J91_08365) mdaB 1788886..1789467 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  I6J91_RS08370 (I6J91_08370) ygiN 1789498..1789812 (+) 315 WP_000633738.1 putative quinol monooxygenase -
  I6J91_RS08375 (I6J91_08375) - 1789857..1790744 (-) 888 WP_000614943.1 MurR/RpiR family transcriptional regulator -
  I6J91_RS08380 (I6J91_08380) - 1790741..1791688 (-) 948 WP_001468195.1 iron-siderophore ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24687.63 Da        Isoelectric Point: 6.9850

>NTDB_id=466732 I6J91_RS08355 WP_001221493.1 1786771..1787430(+) (ciaR) [Escherichia coli strain FDAARGOS_1261]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=466732 I6J91_RS08355 WP_001221493.1 1786771..1787430(+) (ciaR) [Escherichia coli strain FDAARGOS_1261]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCGGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCTGTATTGATCCTGACTGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGCAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3YXL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365