Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   JQM34_RS07525 Genome accession   NZ_CP069427
Coordinates   1583748..1585697 (+) Length   649 a.a.
NCBI ID   WP_200370736.1    Uniprot ID   -
Organism   Streptococcus oralis strain SF100     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1578748..1590697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JQM34_RS07505 (JQM34_0001529) argR 1579572..1580018 (+) 447 WP_001231483.1 arginine repressor -
  JQM34_RS07510 (JQM34_0001530) hexA 1580069..1582603 (+) 2535 WP_200370733.1 DNA mismatch repair protein MutS Machinery gene
  JQM34_RS07515 (JQM34_0001531) - 1582644..1583102 (-) 459 WP_200370734.1 DUF3021 domain-containing protein -
  JQM34_RS07520 (JQM34_0001532) - 1583099..1583539 (-) 441 WP_200370735.1 LytTR family DNA-binding domain-containing protein -
  JQM34_RS07525 (JQM34_0001533) hexB 1583748..1585697 (+) 1950 WP_200370736.1 DNA mismatch repair endonuclease MutL Machinery gene
  JQM34_RS07530 (JQM34_0001534) - 1585849..1586349 (-) 501 WP_200370737.1 helix-turn-helix transcriptional regulator -
  JQM34_RS07535 (JQM34_0001535) - 1586519..1587751 (+) 1233 WP_200370738.1 MFS transporter -
  JQM34_RS07540 (JQM34_0001536) ruvA 1587764..1588357 (+) 594 WP_200370739.1 Holliday junction branch migration protein RuvA Machinery gene
  JQM34_RS07545 (JQM34_0001537) - 1588367..1588933 (+) 567 WP_200370741.1 DNA-3-methyladenine glycosylase I -
  JQM34_RS07550 (JQM34_0001538) - 1589013..1589276 (-) 264 WP_000166112.1 SemiSWEET family transporter -
  JQM34_RS07555 (JQM34_0001539) - 1589382..1590416 (-) 1035 WP_200370742.1 S66 peptidase family protein -

Sequence

Protein


Download         Length: 649 a.a.        Molecular weight: 73348.79 Da        Isoelectric Point: 5.6136

>NTDB_id=466545 JQM34_RS07525 WP_200370736.1 1583748..1585697(+) (hexB) [Streptococcus oralis strain SF100]
MSHIIELPEVLANQIAAGEVIERPASVVKELLENAIDAGSSQIIIEIEEAGLKKIQITDNGHGIAHDEVELALRRHATSK
IKNQADLFRIRTLGFRGEALPSIASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLASAKKMIAIENSDLDFEISGFVSLP
ELTRANRNYISLFINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKERELMALVSE
AISNSLKEQALIPDALENLAKSTVRNRQKVEQTILPLKENTLYYEKTELSKPSQAEVADHQVELTEEGRDLTLFAKETLD
QLTKPAKLHFAERKPASYDQLDHPELDLASLDKAYDKLEREESSSFPELEFFGQMHGTYLFAQGRDGLYIIDQHAAQERV
KYEEYRESIGNVDQSQQQLLVPYIFEFPADDALRLKERMHLLEEVGVFLAEYGENQFILREHPIWMTEEEIESGIYEMCD
MLLLTKEVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHFTKSDMEKMFRRIQENH
TSLRELGKY

Nucleotide


Download         Length: 1950 bp        

>NTDB_id=466545 JQM34_RS07525 WP_200370736.1 1583748..1585697(+) (hexB) [Streptococcus oralis strain SF100]
ATGTCTCATATTATTGAATTGCCAGAGGTACTGGCAAACCAGATTGCGGCAGGAGAAGTGATTGAACGTCCTGCCAGTGT
AGTCAAAGAGCTGTTAGAAAATGCCATTGACGCGGGTTCTAGCCAGATTATCATTGAGATCGAGGAAGCTGGTCTTAAGA
AGATTCAAATCACAGATAATGGCCATGGAATTGCCCACGATGAGGTGGAATTGGCCCTGCGTCGTCATGCGACCAGTAAG
ATAAAAAATCAGGCAGACCTCTTTCGGATTCGGACGCTTGGTTTTCGTGGTGAAGCCCTGCCTTCGATCGCTTCTGTCAG
TGTCTTGACTCTGTTGACGGCGGTGGATGGTGCGAGTCATGGGACCAAGCTCGTTGCGCGTGGGGGTGAAGTTGAGGAAG
TCATCCCAGCGACTAGTCCTGTGGGAACCAAAGTTTGTGTGGAGGACCTCTTTTTCAATACACCAGCTCGTCTCAAGTAT
ATGAAGAGTCAGCAGGCAGAGTTATCCCATATCATTGATATTGTCAACCGTCTAGGGTTAGCCCATCCTGAGATTTCTTT
TAGTTTAATCAGTGATGGCAAGGAAATGACGCGGACAGCAGGGACTGGTCAACTACGCCAAGCCATCGCAGGGATTTACG
GTTTAGCAAGCGCTAAAAAGATGATTGCTATTGAAAACTCTGACTTAGATTTCGAAATTTCAGGTTTTGTGTCCTTACCT
GAGTTGACTCGTGCAAACCGCAACTATATCAGTCTCTTTATCAATGGCCGTTATATCAAAAACTTCCTGCTCAACCGTGC
TATTTTAGATGGTTACGGCAGCAAGCTCATGGTGGGGCGTTTCCCACTGGCTGTCATTCACATCCATATTGATCCTTATC
TGGCTGATGTCAATGTGCATCCAACCAAGCAAGAAGTGCGGATTTCTAAGGAAAGAGAACTGATGGCGCTGGTTTCAGAA
GCTATTTCAAATAGTCTCAAGGAACAAGCCTTGATTCCTGATGCTTTAGAAAATCTTGCCAAGTCGACCGTGCGCAATCG
TCAAAAGGTAGAGCAAACTATTCTCCCACTCAAAGAAAATACGCTTTACTATGAAAAAACAGAACTCTCAAAACCCAGTC
AAGCTGAGGTGGCTGACCACCAGGTTGAATTAACTGAGGAGGGTAGGGACCTAACCCTGTTTGCCAAGGAAACCTTGGAC
CAGTTGACCAAGCCTGCAAAACTGCATTTTGCAGAAAGAAAACCAGCTAGCTATGACCAATTAGACCATCCAGAGTTAGA
CTTAGCCAGTCTTGATAAGGCTTATGACAAGCTGGAGAGAGAAGAATCATCCAGCTTTCCAGAGTTGGAGTTTTTCGGAC
AAATGCATGGGACCTATCTCTTTGCTCAAGGTAGAGATGGGCTTTACATCATAGATCAGCATGCGGCACAGGAACGGGTC
AAATACGAGGAATACCGAGAGAGCATTGGCAATGTTGACCAGAGTCAGCAACAACTCCTAGTGCCCTACATCTTTGAATT
CCCAGCGGATGATGCCCTTCGTCTTAAAGAAAGAATGCATCTTTTGGAGGAAGTGGGCGTCTTTCTAGCAGAGTATGGAG
AAAATCAATTCATCCTGCGTGAACATCCCATCTGGATGACCGAAGAGGAAATCGAATCTGGTATCTATGAAATGTGCGAC
ATGCTCCTCTTGACTAAAGAAGTTTCGATTAAGAAATACCGAGCAGAGTTGGCCATTATGATGTCCTGCAAGCGGTCGAT
CAAGGCCAACCATCGTATCGATGACCACTCGGCTAGACAACTCCTCTACCAACTCTCTCAATGCGACAACCCATATAACT
GTCCTCATGGACGTCCTGTTTTGGTGCATTTCACCAAGTCAGATATGGAAAAGATGTTCCGACGTATTCAGGAAAATCAC
ACCAGCCTCCGAGAGTTGGGGAAATATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(450-592)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-107)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

96.456

100

0.965