Detailed information NTG0466544

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: JQM34_RS07510
• Genome accession: NZ_CP069427
• Coordinates: 1580069..1582603 (+)
• Length: 844 a.a.
• NCBI ID: WP_200370733.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SF100
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1575069..1587603

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JQM34_RS07485 (JQM34_0001525)	nrdI	1575137..1575607 (+)	471	WP_044021503.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
JQM34_RS07490 (JQM34_0001526)	-	1575689..1576951 (-)	1263	WP_070656858.1	NRAMP family divalent metal transporter	-
JQM34_RS07495 (JQM34_0001527)	-	1577150..1577395 (-)	246	WP_000084865.1	hypothetical protein	-
JQM34_RS07500 (JQM34_0001528)	argS	1577726..1579417 (-)	1692	WP_200370729.1	arginine--tRNA ligase	-
JQM34_RS07505 (JQM34_0001529)	argR	1579572..1580018 (+)	447	WP_001231483.1	arginine repressor	-
JQM34_RS07510 (JQM34_0001530)	hexA	1580069..1582603 (+)	2535	WP_200370733.1	DNA mismatch repair protein MutS	Machinery gene
JQM34_RS07515 (JQM34_0001531)	-	1582644..1583102 (-)	459	WP_200370734.1	DUF3021 domain-containing protein	-
JQM34_RS07520 (JQM34_0001532)	-	1583099..1583539 (-)	441	WP_200370735.1	LytTR family DNA-binding domain-containing protein	-
JQM34_RS07525 (JQM34_0001533)	hexB	1583748..1585697 (+)	1950	WP_200370736.1	DNA mismatch repair endonuclease MutL	Machinery gene
JQM34_RS07530 (JQM34_0001534)	-	1585849..1586349 (-)	501	WP_200370737.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 844 a.a.
• Molecular weight: 94723.20 Da
• Isoelectric Point: 4.8632

>NTDB_id=466544 JQM34_RS07510 WP_200370733.1 1580069..1582603(+) (hexA) [Streptococcus oralis strain SF100]
MATEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAINAAQILEISLTSRNKNAENPIPMAGVPYHSAQQYIDVLI
EQGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSGKPDSQNNFLVSLDCDGNQFGLAYMDLVTGDFYVTGLLDFTL
VCGEVRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKEGFEDLHLLDSRLAAVEQAAASKLLQYVHRTQMRELNHLKP
VIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLFWLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQDVVQVFLDHFF
ERSDLTDSLKGVYDIERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIKQLDAIPELESLISAAIAP
EAPHVITEGGIIRTGFDETLDKYRRVLREGTSWIAEIEAKERENSGISTLKIDYNKKDGYYFHVTNSQLGNVPAHFFRKA
TLKNSERFGTEELARIEGDMLEAREKSANLEYEIFMRIREEVSKYIQRLQALAQGIATIDVLQSLAVVAETQHLIRPEFG
EDSQIDIQKGRHAVVEKVMGAQTYIPNSIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQLGSYVPAERAHLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANNAISHATKDSLILFDELGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHEL
TSLESSLEHLVNVHVATLEQDGQVTFLHKIEPGPADKSYGIHVAKIAGLPGELLARADKILTQLESQGTESPVPMRETSA
ITEQMSLFDAPEEHPILAELAKLDVYNMTPMQAMNVLVELKQKL

Nucleotide

• Length: 2535 bp

>NTDB_id=466544 JQM34_RS07510 WP_200370733.1 1580069..1582603(+) (hexA) [Streptococcus oralis strain SF100]
ATGGCAACAGAAAAGCTATCACCCGGCATGCAACAGTATGTGGATATTAAGAAACAATACCCAGATGCTTTTTTGCTTTT
TCGAATGGGTGATTTTTACGAGTTGTTCTATGAAGATGCAATTAATGCAGCACAGATTTTAGAAATTTCCTTAACGAGTC
GGAATAAAAATGCAGAAAATCCGATACCTATGGCGGGCGTCCCCTATCATTCTGCCCAGCAGTATATCGATGTTCTGATT
GAGCAGGGCTATAAGGTAGCCATAGCCGAGCAGATGGAAGATCCCAAACAAGCAGTTGGTGTTGTCAAGCGAGAGGTGGT
CCAGGTCATCACACCTGGAACGGTCGTTGATAGCGGTAAGCCGGATAGTCAGAATAATTTCTTGGTTTCCTTAGATTGTG
ATGGCAATCAATTTGGTCTGGCTTATATGGATTTGGTGACGGGTGACTTTTATGTGACGGGGCTATTGGATTTCACGTTG
GTTTGTGGGGAAGTCCGTAACCTCAAGGCGCGAGAAGTGGTGCTGGGTTATGACTTGTCTGAGGAAGAAGAACAAATTCT
CAGTCGCCAGATGAATCTGGTGCTTTCCTATGAGAAGGAAGGCTTTGAGGACCTTCATTTACTGGATTCACGTTTGGCAG
CTGTGGAGCAAGCGGCAGCTAGTAAGCTCCTCCAGTATGTTCACCGTACCCAGATGCGAGAATTGAACCATCTCAAACCA
GTTATCCGCTATGAAATTAAAGATTTCTTGCAGATGGATTATGCGACCAAGGCTAGTTTAGATTTGGTTGAGAATGCCCG
TTCAGGCAAGAAGCAAGGCAGTCTTTTCTGGCTTTTAGATGAAACCAAAACAGCTATGGGAATGCGACTCTTGCGTTCTT
GGATCCATCGTCCTTTGATTGATAAGGAGCGAATCGTCCAACGTCAAGACGTGGTGCAGGTCTTTCTTGACCACTTCTTT
GAGCGTAGTGATTTAACGGACAGTCTCAAGGGTGTTTATGATATCGAACGCTTGGCTAGTCGGGTTTCTTTTGGCAAGAC
CAATCCCAAGGATCTCTTGCAACTAGCGACCACCTTGTCTAGTGTACCACGGATTCGTGCGATTTTAGAAGGCATGGAGC
AACCTGCCCTGGCCTATCTTATCAAACAGTTAGATGCCATTCCAGAGTTAGAGAGCTTGATTAGTGCTGCTATTGCTCCT
GAAGCTCCTCATGTGATTACGGAAGGTGGCATTATCCGTACGGGATTTGATGAGACCTTAGACAAGTACCGTCGTGTGCT
CAGAGAAGGGACTAGCTGGATTGCTGAGATTGAGGCTAAGGAGCGGGAAAACTCTGGCATCAGCACGCTTAAGATTGACT
ACAATAAAAAGGACGGCTACTATTTCCATGTGACTAATTCGCAACTGGGAAATGTGCCAGCCCACTTTTTCCGCAAGGCG
ACGCTGAAAAACTCAGAACGCTTTGGTACCGAAGAATTGGCCCGTATCGAAGGGGATATGTTGGAGGCGCGTGAGAAGTC
AGCCAACCTAGAATATGAAATCTTTATGCGCATCCGTGAAGAAGTCAGCAAGTACATCCAGCGTTTGCAGGCTTTAGCAC
AAGGAATTGCGACGATTGATGTTTTGCAAAGTCTGGCGGTTGTAGCTGAAACCCAGCATTTGATTCGACCTGAGTTTGGA
GAAGATTCACAAATAGATATCCAAAAAGGGCGCCATGCTGTCGTCGAAAAGGTCATGGGAGCTCAGACCTATATTCCAAA
CAGTATCCAGATGGCAGAAGATACGAGTATTCAGCTAATTACAGGGCCCAACATGAGTGGGAAGTCAACCTACATGCGCC
AGTTAGCCATGACTGCGGTTATGGCCCAGCTGGGTTCTTATGTGCCGGCAGAAAGAGCTCATTTGCCGATTTTCGATGCC
ATCTTTACCCGTATCGGAGCAGCAGATGACTTGGTTTCAGGTCAATCAACCTTCATGGTGGAGATGATGGAGGCCAACAA
TGCCATTTCGCATGCGACTAAGGACTCACTCATTCTTTTCGATGAATTGGGACGGGGAACGGCAACCTATGATGGCATGG
CTCTTGCCCAGTCCATCATCGAATACATTCATGAACATATCGGAGCCAAGACCCTCTTTGCGACCCACTACCATGAGTTG
ACCAGTCTGGAGTCTAGCTTGGAACACTTGGTCAATGTTCATGTGGCAACCTTGGAGCAGGATGGGCAGGTCACCTTCCT
TCACAAGATCGAACCAGGACCAGCTGACAAATCCTATGGTATCCATGTTGCTAAGATCGCTGGATTACCAGGAGAACTTT
TAGCAAGAGCGGATAAGATTTTAACGCAACTGGAGAGTCAAGGGACGGAAAGTCCTGTTCCGATGAGAGAAACAAGTGCT
ATCACAGAGCAGATGTCACTCTTTGATGCACCTGAAGAACATCCTATCCTAGCAGAATTAGCTAAACTGGATGTGTACAA
TATGACACCGATGCAGGCTATGAACGTCTTGGTCGAGCTCAAACAAAAGTTATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-117)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	95.616	100	0.956
mutS	Pseudomonas stutzeri strain ATCC 17587	37.237	100	0.377