Detailed information NTG0046604

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: SARLGA251_RS08035
• Genome accession: NC_017349
• Coordinates: 1646668..1648869 (-)
• Length: 733 a.a.
• NCBI ID: WP_041201403.1
• Uniprot ID: -
• Organism: Staphylococcus aureus subsp. aureus LGA251
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1641668..1653869

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SARLGA251_RS08020 (SARLGA251_14900)	lepA	1643172..1644995 (-)	1824	WP_000368338.1	translation elongation factor 4	-
SARLGA251_RS08025 (SARLGA251_14910)	rpsT	1645341..1645592 (+)	252	WP_001274017.1	30S ribosomal protein S20	-
SARLGA251_RS08030 (SARLGA251_14920)	holA	1645637..1646611 (-)	975	WP_001282572.1	DNA polymerase III subunit delta	-
SARLGA251_RS08035 (SARLGA251_14930)	comEC	1646668..1648869 (-)	2202	WP_041201403.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SARLGA251_RS08040 (SARLGA251_14940)	-	1648874..1649335 (-)	462	WP_000439693.1	ComE operon protein 2	-
SARLGA251_RS08045 (SARLGA251_14950)	comEA	1649427..1650113 (-)	687	WP_078064626.1	ComEA family DNA-binding protein	Machinery gene
SARLGA251_RS08050 (SARLGA251_14960)	-	1650153..1650869 (-)	717	WP_000084829.1	class I SAM-dependent DNA methyltransferase	-
SARLGA251_RS08055 (SARLGA251_14970)	rsfS	1650872..1651225 (-)	354	WP_001088019.1	ribosome silencing factor	-
SARLGA251_RS08060 (SARLGA251_14980)	yqeK	1651226..1651810 (-)	585	WP_001019324.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
SARLGA251_RS08065 (SARLGA251_14990)	nadD	1651800..1652369 (-)	570	WP_000725161.1	nicotinate (nicotinamide) nucleotide adenylyltransferase	-
SARLGA251_RS08070 (SARLGA251_15000)	yhbY	1652372..1652662 (-)	291	WP_000955234.1	ribosome assembly RNA-binding protein YhbY	-
SARLGA251_RS08075 (SARLGA251_15010)	aroE	1652666..1653472 (-)	807	WP_000666747.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 733 a.a.
• Molecular weight: 84898.92 Da
• Isoelectric Point: 10.0424

>NTDB_id=46604 SARLGA251_RS08035 WP_041201403.1 1646668..1648869(-) (comEC) [Staphylococcus aureus subsp. aureus LGA251]
MLYVALSMIVGVLWNSSKVLSTFLFILLLYIAYRKNKIVYAPISLFLIIFSSWYLHYSQQAIFNYINYIERNSQFNERAQ
VIQIQRQGSDTYKGRLSLKNEIYPFFLTNKKNFDLKKIESRNCIVKGQFKVNDNKFVTLKLQSIVVQSCLESNRSNLIEK
HKQFIMNRIYDSSIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAIVFLIYQPLKRLNLPLFVIKGIT
IIVLALFAQYTNYAPSAVRAIIMTTLVLLITKQIKIKGIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQ
QLSKLQSLFIITFIAQLASFIVAIPNFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTSLNYLADLSFNFH
DWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRKYILVTFWTIIILTLLITFPTNSHHKITMLNVGQGDSI
LYEGGKNQNVLIDTGGKVIDDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGEVEYIISHIKIKHIVIYNKG
YSSNTLMLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNESLLL
KKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNL
KVDSNSYGNASGL

Nucleotide

• Length: 2202 bp

>NTDB_id=46604 SARLGA251_RS08035 WP_041201403.1 1646668..1648869(-) (comEC) [Staphylococcus aureus subsp. aureus LGA251]
TTGCTGTATGTCGCATTATCAATGATTGTAGGAGTGCTTTGGAATTCTAGCAAAGTGCTCTCTACATTTCTTTTCATTTT
ACTTTTGTATATTGCTTATCGTAAAAATAAAATCGTTTATGCCCCTATTTCTCTCTTTTTAATCATTTTCTCCTCATGGT
ATTTACATTATTCACAACAAGCAATTTTTAATTATATCAATTATATTGAACGTAATTCTCAGTTTAATGAGCGTGCTCAA
GTAATCCAAATTCAACGTCAAGGTAGTGACACATATAAAGGTAGGTTAAGTTTAAAAAATGAAATATATCCTTTCTTTTT
AACAAATAAAAAGAATTTTGATTTAAAGAAAATTGAAAGTCGTAATTGTATTGTTAAAGGACAATTCAAAGTTAATGACA
ATAAGTTTGTAACTCTTAAATTACAAAGTATAGTTGTACAAAGCTGTCTAGAATCGAACCGGTCTAATTTAATTGAGAAA
CATAAACAGTTTATAATGAATCGAATTTATGATTCGAGTATTAAGTTTCCGGATCGTATTATGGCATTGATTACTGGTGA
CGTAAAAGAAATTAATGAGCAATTTAAGGAACGTGTTAAAGAGATAGGTATATATCATTTGCTGGCAGTTAGTGGCTCGC
ATATAGCTGCAATTGTATTCTTAATTTACCAACCTTTAAAACGATTAAATTTACCTTTATTTGTCATTAAAGGAATTACA
ATCATTGTATTAGCTTTATTTGCTCAATACACAAATTATGCACCTAGTGCTGTAAGAGCTATAATAATGACAACTCTTGT
ATTGCTTATTACTAAGCAAATTAAAATAAAGGGTATTCAGCTATTAGCATTTGCATTTATAATTATGTTTATTTTAAATC
CACTAGTTGTTTATGATATTGGATTTCAATTTTCATTCATCATTTCATTTTTTATTATGCTACTTTTTCCTTTTTTACAG
CAATTGTCAAAGTTACAATCATTATTCATAATTACGTTTATTGCACAATTAGCTTCATTTATCGTTGCCATTCCAAACTT
TCATCAACTTCAATGGGTGGGATTTTTATCTAATTTGATTTTTGTACCGTACTATTCGATTATATTGTTTCCGCTATCTA
TTTTATTCTTTATTACAAGTCATTTTATTGTGGGATTAACGTCGCTAAATTACTTGGCTGACCTAAGTTTTAATTTTCAT
GACTGGTTACTAGACCTATTCACAAGAATCAAGCAATCACATTTTTCTGTTCCCAAGTTTAATGATTGGATATTTATAAT
ATTTATAATTTCTGTTTATTACATATTTTGGTTATTGGCTAAACGTAAATATATATTGGTTACGTTTTGGACTATAATTA
TTCTGACATTATTAATAACGTTTCCAACAAATTCACATCACAAAATTACAATGTTAAATGTGGGGCAGGGAGACAGTATT
TTATATGAAGGTGGTAAGAACCAAAATGTCTTGATTGATACAGGTGGGAAAGTGATTGATGACACTAAACAACCTAGTTA
TTCAATTTCTAAATATCATATTTTACCAACGCTAAATGAAAGAGGGATAAATGAATTAGAGTATCTAATTTTAACACATC
CACACAATGACCATATTGGTGAAGTGGAATATATTATTAGTCATATTAAAATTAAACATATAGTGATATACAATAAGGGA
TATAGTAGTAATACATTGATGTTATTATCGAAATTAAGCCATAAGTATAACATTAAACTTATGGATGTAAGACAAGTTAG
TAGTTTTAAACTTGGAGATAGTAGTTTTCTATTTTTTGATAGTTTTATTCCAAATAGCCGAGATAAAAATGAATATTCGA
TTATTACTATGATTACATATCAAAATAAAAAAGTTTTATTAATGGGCGATGCTAGTAAAAATAATGAATCTTTACTACTA
AAAAAATATAACTTGCCGGAGATTGATATTTTAAAAGTAGGACATCATGGGAGCAAGACAAGTAGTTCTAAAGAATTTAT
AGAGATGATTAAGCCTAAAATAAGTTTGATTTCTTCTGGAAAGAACAATATGTATCATCTTCCTAACATAGAAGTTGTTA
AACGATTGCAAAGGATTCGCAGTCGCATTTACAATAGTCAACAAAACGGTCAAGTTACAATTGACTTAGATGATAATTTA
AAAGTTGATTCAAACTCTTATGGAAATGCAAGTGGTTTATAG

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (474-679)

• Competence protein (Competence) (183-441)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Staphylococcus aureus N315	98.909	100	0.989
comEC	Staphylococcus aureus MW2	98.772	100	0.988