Detailed information
Bioinformatically predicted
Overview
| Name | comR | Type | Regulator |
| Locus tag | SSU1300283_RS00355 | Genome accession | NZ_CP058741 |
| Coordinates | 59531..60448 (+) | Length | 305 a.a. |
| NCBI ID | WP_002935296.1 | Uniprot ID | - |
| Organism | Streptococcus suis strain 13-00283-02 | ||
| Function | activate transcription of comX (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 13840..58644 | 59531..60448 | flank | 887 |
| IS/Tn | 60857..62059 | 59531..60448 | flank | 409 |
Gene organization within MGE regions
Location: 13840..62059
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SSU1300283_RS00070 (SSU1300283_00015) | ftsH | 13840..15810 (+) | 1971 | WP_004194314.1 | ATP-dependent zinc metalloprotease FtsH | - |
| SSU1300283_RS10970 | - | 16136..16577 (+) | 442 | Protein_15 | sigma-70 family RNA polymerase sigma factor | - |
| SSU1300283_RS00180 (SSU1300283_00037) | mreC | 23880..24716 (+) | 837 | WP_009908845.1 | rod shape-determining protein MreC | - |
| SSU1300283_RS00185 (SSU1300283_00038) | mreD | 24733..25221 (+) | 489 | WP_009908846.1 | rod shape-determining protein MreD | - |
| SSU1300283_RS00190 (SSU1300283_00039) | pcsB | 25306..26562 (+) | 1257 | WP_002935338.1 | peptidoglycan hydrolase PcsB | - |
| SSU1300283_RS00195 (SSU1300283_00040) | - | 26665..27633 (+) | 969 | WP_002935337.1 | ribose-phosphate diphosphokinase | - |
| SSU1300283_RS00200 (SSU1300283_00041) | - | 27720..28898 (+) | 1179 | WP_002935336.1 | pyridoxal phosphate-dependent aminotransferase | - |
| SSU1300283_RS00205 (SSU1300283_00042) | recO | 28885..29667 (+) | 783 | WP_002935335.1 | DNA repair protein RecO | - |
| SSU1300283_RS00210 (SSU1300283_00043) | plsX | 29664..30671 (+) | 1008 | WP_002935334.1 | phosphate acyltransferase PlsX | - |
| SSU1300283_RS00215 (SSU1300283_00044) | - | 30664..30912 (+) | 249 | WP_002935333.1 | phosphopantetheine-binding protein | - |
| SSU1300283_RS00220 (SSU1300283_00045) | purC | 31030..31737 (+) | 708 | WP_002935328.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| SSU1300283_RS00225 (SSU1300283_00046) | - | 31750..35469 (+) | 3720 | WP_014636740.1 | phosphoribosylformylglycinamidine synthase | - |
| SSU1300283_RS00230 (SSU1300283_00047) | purF | 35472..36926 (+) | 1455 | WP_002935326.1 | amidophosphoribosyltransferase | - |
| SSU1300283_RS00235 (SSU1300283_00048) | purM | 36982..38004 (+) | 1023 | WP_009908859.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| SSU1300283_RS00240 (SSU1300283_00049) | purN | 38001..38552 (+) | 552 | WP_009908860.1 | phosphoribosylglycinamide formyltransferase | - |
| SSU1300283_RS00245 (SSU1300283_00050) | purH | 38562..40109 (+) | 1548 | WP_002935323.1 | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | - |
| SSU1300283_RS00250 (SSU1300283_00051) | - | 40174..41004 (+) | 831 | WP_002935322.1 | DNA adenine methylase | - |
| SSU1300283_RS00255 (SSU1300283_00052) | - | 40994..41809 (+) | 816 | WP_032499218.1 | site-specific DNA-methyltransferase | - |
| SSU1300283_RS10905 (SSU1300283_00053) | - | 41787..42347 (+) | 561 | WP_256791905.1 | type II restriction endonuclease | - |
| SSU1300283_RS10910 | - | 42385..42714 (+) | 330 | WP_256791907.1 | type II restriction endonuclease | - |
| SSU1300283_RS00265 | - | 42714..43611 (+) | 898 | Protein_34 | type II restriction endonuclease | - |
| SSU1300283_RS00270 (SSU1300283_00056) | purD | 43732..44994 (+) | 1263 | WP_002935318.1 | phosphoribosylamine--glycine ligase | - |
| SSU1300283_RS00275 (SSU1300283_00057) | purE | 45020..45508 (+) | 489 | WP_002935317.1 | 5-(carboxyamino)imidazole ribonucleotide mutase | - |
| SSU1300283_RS00280 (SSU1300283_00058) | purK | 45495..46580 (+) | 1086 | WP_002935314.1 | 5-(carboxyamino)imidazole ribonucleotide synthase | - |
| SSU1300283_RS00285 (SSU1300283_00059) | - | 46567..47490 (+) | 924 | WP_002935313.1 | DUF4268 domain-containing protein | - |
| SSU1300283_RS00290 (SSU1300283_00060) | purB | 47525..48817 (+) | 1293 | WP_013730055.1 | adenylosuccinate lyase | - |
| SSU1300283_RS00295 (SSU1300283_00061) | - | 49326..50150 (+) | 825 | WP_002935311.1 | ABC transporter ATP-binding protein | - |
| SSU1300283_RS00300 (SSU1300283_00062) | - | 50143..50877 (+) | 735 | WP_002935310.1 | ABC transporter permease | - |
| SSU1300283_RS00305 (SSU1300283_00063) | - | 51212..51940 (+) | 729 | WP_002935309.1 | DUF2705 family protein | - |
| SSU1300283_RS00310 (SSU1300283_00064) | - | 51950..52528 (+) | 579 | WP_002935308.1 | CPBP family intramembrane glutamic endopeptidase | - |
| SSU1300283_RS00315 (SSU1300283_00065) | - | 52543..52971 (+) | 429 | WP_002935307.1 | Msa family membrane protein | - |
| SSU1300283_RS00320 (SSU1300283_00066) | - | 52964..53836 (+) | 873 | WP_002935305.1 | ABC transporter ATP-binding protein | - |
| SSU1300283_RS00325 (SSU1300283_00067) | - | 53842..54612 (+) | 771 | WP_002935304.1 | membrane protein | - |
| SSU1300283_RS00330 (SSU1300283_00068) | - | 54615..56327 (+) | 1713 | WP_002935303.1 | ABC transporter ATP-binding protein | - |
| SSU1300283_RS00335 (SSU1300283_00069) | - | 56429..56602 (+) | 174 | WP_014636741.1 | hypothetical protein | - |
| SSU1300283_RS00340 (SSU1300283_00070) | ruvB | 56897..57898 (+) | 1002 | WP_002935300.1 | Holliday junction branch migration DNA helicase RuvB | - |
| SSU1300283_RS00345 (SSU1300283_00071) | - | 57898..58644 (+) | 747 | WP_002935299.1 | GNAT family N-acetyltransferase | - |
| SSU1300283_RS00350 (SSU1300283_00072) | - | 58646..59284 (+) | 639 | WP_002935298.1 | HAD-IA family hydrolase | - |
| SSU1300283_RS00355 (SSU1300283_00073) | comR | 59531..60448 (+) | 918 | WP_002935296.1 | helix-turn-helix domain-containing protein | Regulator |
| SSU1300283_RS00360 (SSU1300283_00074) | - | 60857..62059 (-) | 1203 | WP_002935295.1 | IS110-like element ISSsu7 family transposase | - |
Sequence
Protein
Download Length: 305 a.a. Molecular weight: 36252.32 Da Isoelectric Point: 4.6744
>NTDB_id=465172 SSU1300283_RS00355 WP_002935296.1 59531..60448(+) (comR) [Streptococcus suis strain 13-00283-02]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIVVDTLCSLFDVLDTDSQEYGKEILDDYLHQSYHRSKLSIND
LMILRLFIEHCQLEDLSVGTSNYALFTDLIEKLPQSIYDVHSESLFIVRDLFLAIVRILFSKELYNHIPVYIEKIENIME
LSQDFQKKPILNLVKWKYELKVQHNHEIAERYYNEAITFASLLNQFHLKEKLQMEWEKDTQSLKR
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIVVDTLCSLFDVLDTDSQEYGKEILDDYLHQSYHRSKLSIND
LMILRLFIEHCQLEDLSVGTSNYALFTDLIEKLPQSIYDVHSESLFIVRDLFLAIVRILFSKELYNHIPVYIEKIENIME
LSQDFQKKPILNLVKWKYELKVQHNHEIAERYYNEAITFASLLNQFHLKEKLQMEWEKDTQSLKR
Nucleotide
Download Length: 918 bp
>NTDB_id=465172 SSU1300283_RS00355 WP_002935296.1 59531..60448(+) (comR) [Streptococcus suis strain 13-00283-02]
ATGAACGATAAGGAGTTTGGACAGCGTGTGCGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAAATAGTTGTAGACACCCTATGTTCCCTATTTGATGTATTGGATACAG
ATAGCCAGGAATACGGTAAAGAAATTCTTGATGATTATTTACATCAAAGCTATCACCGTTCCAAACTATCTATAAACGAT
TTAATGATTTTGCGATTATTTATTGAACATTGTCAGTTGGAGGATTTATCTGTTGGAACTTCCAATTATGCTTTATTTAC
AGATTTGATAGAGAAATTGCCTCAATCAATCTATGATGTACATTCGGAATCCTTATTCATTGTCCGCGATTTATTTCTAG
CTATTGTTCGTATTTTATTTTCGAAGGAGTTGTATAATCATATTCCAGTCTATATAGAAAAAATAGAAAACATCATGGAA
TTATCACAAGATTTTCAGAAGAAGCCAATTCTAAATCTTGTGAAATGGAAATATGAATTAAAGGTACAACATAATCATGA
AATTGCTGAGAGGTACTATAATGAAGCGATTACATTTGCCAGCCTACTAAATCAATTTCACTTGAAAGAAAAACTGCAAA
TGGAATGGGAAAAAGATACGCAGAGTCTAAAAAGATGA
ATGAACGATAAGGAGTTTGGACAGCGTGTGCGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAAATAGTTGTAGACACCCTATGTTCCCTATTTGATGTATTGGATACAG
ATAGCCAGGAATACGGTAAAGAAATTCTTGATGATTATTTACATCAAAGCTATCACCGTTCCAAACTATCTATAAACGAT
TTAATGATTTTGCGATTATTTATTGAACATTGTCAGTTGGAGGATTTATCTGTTGGAACTTCCAATTATGCTTTATTTAC
AGATTTGATAGAGAAATTGCCTCAATCAATCTATGATGTACATTCGGAATCCTTATTCATTGTCCGCGATTTATTTCTAG
CTATTGTTCGTATTTTATTTTCGAAGGAGTTGTATAATCATATTCCAGTCTATATAGAAAAAATAGAAAACATCATGGAA
TTATCACAAGATTTTCAGAAGAAGCCAATTCTAAATCTTGTGAAATGGAAATATGAATTAAAGGTACAACATAATCATGA
AATTGCTGAGAGGTACTATAATGAAGCGATTACATTTGCCAGCCTACTAAATCAATTTCACTTGAAAGAAAAACTGCAAA
TGGAATGGGAAAAAGATACGCAGAGTCTAAAAAGATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comR | Streptococcus suis D9 |
100 |
100 |
1 |
| comR | Streptococcus suis P1/7 |
62.126 |
98.689 |
0.613 |
| comR | Streptococcus suis 05ZYH33 |
62.126 |
98.689 |
0.613 |
| comR | Streptococcus mutans UA159 |
37 |
98.361 |
0.364 |