Detailed information NTG0463499

Bioinformatically predicted

Overview

• Name: comA/comEC
• Type: Machinery gene
• Locus tag: HTZ92_RS03195
• Genome accession: NZ_CP058289
• Coordinates: 682008..684440 (+)
• Length: 810 a.a.
• NCBI ID: WP_000472725.1
• Uniprot ID: A0A6F8TDY5
• Organism: Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841 strain ATCC 19606
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	676979..689117	682008..684440	within	0

Gene organization within MGE regions

Location: 676979..689117

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HTZ92_RS03170 (HTZ92_0597)	-	677159..678100 (-)	942	WP_000795874.1	hypothetical protein	-
HTZ92_RS03175 (HTZ92_0598)	-	678357..678842 (+)	486	WP_001985538.1	YaiI/YqxD family protein	-
HTZ92_RS03180 (HTZ92_0599)	-	678853..679761 (+)	909	WP_001140081.1	DMT family transporter	-
HTZ92_RS18880	-	679791..679871 (-)	81	Protein_601	PilZ domain-containing protein	-
HTZ92_RS03185 (HTZ92_0600)	-	680009..681244 (+)	1236	WP_001984636.1	lipoprotein-releasing ABC transporter permease subunit	-
HTZ92_RS03190 (HTZ92_0601)	lolD	681237..681923 (+)	687	WP_000049406.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
HTZ92_RS03195 (HTZ92_0602)	comA/comEC	682008..684440 (+)	2433	WP_000472725.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
HTZ92_RS03200 (HTZ92_0603)	-	684393..685376 (-)	984	WP_001984639.1	lysophospholipid acyltransferase family protein	-
HTZ92_RS03205 (HTZ92_0604)	sppA	685513..686529 (+)	1017	WP_001286607.1	signal peptide peptidase SppA	-
HTZ92_RS03210 (HTZ92_0605)	-	686548..687357 (+)	810	WP_000114071.1	alpha/beta fold hydrolase	-
HTZ92_RS03215 (HTZ92_0606)	purN	687421..688050 (-)	630	WP_000975526.1	phosphoribosylglycinamide formyltransferase	-
HTZ92_RS03220 (HTZ92_0607)	purM	688047..689117 (-)	1071	WP_000071984.1	phosphoribosylformylglycinamidine cyclo-ligase	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 92398.75 Da
• Isoelectric Point: 8.7619

>NTDB_id=463499 HTZ92_RS03195 WP_000472725.1 682008..684440(+) (comA/comEC) [Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841 strain ATCC 19606]
MFKIILLGWIGGIALMGIDFPLIMQYEKVGKALLLLAFIFYLYKRPMFGDRPFLKAVFCLLCTTSLFMVGYHYAEKALIE
RLEQRETDTRNLDIIVYINRLSEEKDNKVQQTAQVLNLSKEPVNWLLYLKSNNQNLLKNNQNLELGHYYRISGKTRPAHS
YATPGAFDQEKWFIQRNIMSGFNVRYIEPLSLDEIYRLGYQQHLKEQQSFSNSFRLNIEKLRLTFRQILNSSSLQQKGLI
LALLTGDESLLSDETQLQFKQLGISHLLAISGPHVLIFAIMLSWACHQFISRYYPQIYLWKPKQVLMAVPCCLGVLIYTA
FVGFEIPALRTLLSAFIFIGFLLLKQPIKPFTLLVYSASLLLLMDPFSVLSAGFWLSYGACFILLRIYQTIAQLPEQHFL
SLSSKMIFMSKVLIESQGKIFIALSPLTLLFFQQISWVAPLTNIIAVPIVGGVIVPLNIMAACAWFVIKPFGNMLFHFND
MLLSILLSCLGLLEKLSLPLQGISLTPLSLLAISCAIIILFLPKGILPKTWGILCCLPLVIMNKTSQQIQLNILDVGQGQ
AIFLQHPEQNWLIDTGGSYDEKIFSIGQNVVVPFLRQQGVRQLDHVVLSHLDQDHSGAFPLIQQEIPVKQLISNEQLPND
LKQPFQYCYQGQQWHYPELDIQILWPKEKDLAFVASNQNQYSCVVYLQFKKVGGYQNFLIMGDAGWEAEYELLKDYPNLK
IDVLVLGHHGSKHSSAYDFLATLKPKLAIASAGFDNRYGHPSQQVIARLKALHIPLKSTVEQGTLSFVLENHKIVLHDRR
LDRLWLSRGF

Nucleotide

• Length: 2433 bp

>NTDB_id=463499 HTZ92_RS03195 WP_000472725.1 682008..684440(+) (comA/comEC) [Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841 strain ATCC 19606]
ATGTTTAAGATTATTCTATTGGGGTGGATTGGCGGTATTGCATTGATGGGAATAGATTTCCCTTTAATCATGCAATATGA
AAAAGTGGGCAAGGCTCTACTGTTACTTGCCTTTATTTTTTATCTTTATAAACGCCCCATGTTCGGTGATCGACCATTTT
TAAAGGCAGTGTTTTGCTTATTATGTACAACAAGTCTTTTTATGGTTGGTTACCACTATGCTGAAAAAGCACTGATTGAA
CGATTAGAACAAAGAGAAACAGATACCCGAAATCTCGACATTATTGTTTATATAAACCGTTTAAGTGAAGAAAAAGATAA
TAAGGTTCAACAAACTGCACAAGTTCTAAATCTTTCTAAAGAACCGGTGAATTGGTTGCTATATTTAAAAAGTAATAATC
AAAATTTATTAAAGAATAATCAGAATCTTGAATTAGGTCACTATTATCGAATATCTGGAAAAACAAGACCTGCGCATAGT
TATGCCACCCCAGGAGCTTTTGATCAGGAAAAGTGGTTTATTCAGCGAAATATTATGTCTGGTTTTAACGTGAGATATAT
TGAGCCTTTAAGCCTTGATGAAATCTATCGATTAGGCTATCAGCAACATTTAAAAGAACAACAGTCTTTTTCCAATAGTT
TTCGTTTAAATATAGAAAAACTTCGCTTAACTTTTAGGCAAATATTAAACAGCTCATCTTTACAGCAAAAGGGTTTAATT
TTAGCTTTGCTGACAGGTGATGAAAGTCTTTTATCAGATGAAACTCAACTACAGTTCAAACAATTAGGAATTAGTCATTT
ATTGGCGATCTCAGGCCCACATGTGCTCATTTTTGCCATTATGTTATCTTGGGCATGTCATCAATTTATTAGTCGTTATT
ATCCTCAAATTTATTTATGGAAACCGAAACAGGTTTTGATGGCTGTACCATGCTGCCTTGGTGTTTTAATTTATACTGCA
TTTGTAGGTTTCGAAATTCCTGCACTACGAACATTATTATCAGCATTTATATTTATTGGTTTTCTATTATTAAAACAACC
TATTAAACCTTTTACATTACTCGTATATAGTGCAAGTCTACTGTTGCTAATGGACCCGTTTAGTGTGCTTTCTGCAGGTT
TTTGGCTGTCTTATGGGGCATGTTTTATTTTATTAAGAATTTACCAAACTATAGCGCAGCTACCTGAGCAACATTTTTTG
AGTCTGAGTTCAAAAATGATTTTTATGAGTAAGGTGTTAATTGAATCTCAAGGCAAAATATTTATTGCATTGAGTCCTTT
AACCTTACTTTTCTTTCAACAAATTTCTTGGGTTGCTCCATTAACCAATATTATTGCCGTGCCTATTGTTGGGGGTGTTA
TTGTCCCTTTAAACATCATGGCTGCTTGCGCATGGTTTGTAATAAAACCATTTGGAAATATGCTTTTTCATTTCAATGAT
ATGTTGCTCAGCATATTGCTGAGTTGTTTGGGCTTATTAGAAAAACTCTCTTTACCATTACAAGGTATAAGCTTGACGCC
ACTGTCTTTATTAGCGATTAGTTGTGCCATTATTATTTTATTTTTACCTAAAGGAATTCTGCCCAAAACTTGGGGAATAT
TATGTTGTTTACCCTTAGTTATTATGAACAAAACGAGTCAGCAAATTCAGCTTAATATTTTAGATGTTGGGCAGGGGCAG
GCTATTTTTCTACAACATCCCGAACAAAACTGGTTAATTGACACAGGCGGTTCTTACGATGAAAAAATATTTAGTATTGG
ACAAAATGTTGTAGTGCCTTTTCTACGTCAGCAAGGCGTAAGACAACTAGATCATGTTGTGCTATCCCATCTTGATCAAG
ACCATAGTGGCGCGTTTCCTCTTATTCAACAAGAGATTCCTGTAAAGCAGCTTATTTCGAATGAACAATTACCAAATGAT
TTAAAGCAACCATTCCAATATTGCTATCAAGGGCAACAATGGCATTATCCTGAGTTAGATATTCAAATTTTATGGCCTAA
AGAAAAAGATCTGGCTTTTGTTGCTTCTAATCAGAATCAATATTCTTGTGTTGTATATCTTCAATTTAAAAAAGTTGGTG
GTTACCAAAATTTTCTTATTATGGGCGATGCTGGATGGGAAGCTGAATACGAGTTATTAAAAGATTATCCTAACTTGAAG
ATAGATGTGTTGGTGCTAGGGCATCATGGAAGTAAGCACAGTTCGGCTTATGATTTCTTGGCGACCTTAAAACCTAAACT
GGCCATTGCATCGGCAGGGTTTGATAACCGTTATGGCCATCCTAGCCAACAAGTTATAGCACGTTTAAAAGCTCTACATA
TTCCGCTAAAAAGCACTGTGGAACAAGGAACCTTAAGTTTTGTGTTGGAAAACCACAAAATAGTTTTACATGACCGACGT
TTGGATAGGCTCTGGTTGAGTAGAGGTTTTTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (243-521)

• Domain of unknown function (DUF4131) (DUF4131) (33-188)

• Metallo-beta-lactamase superfamily (Lactamase_B) (555-645)

3D structure

• AlphaFold DB: A0A6F8TDY5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/comEC	Acinetobacter baumannii D1279779	98.642	100	0.986
comA/comEC	Acinetobacter baumannii strain A118	97.407	100	0.974
comA/comEC	Acinetobacter baylyi ADP1	50.308	100	0.504