Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   JNN66_RS03800 Genome accession   NZ_CP068823
Coordinates   788674..789333 (-) Length   219 a.a.
NCBI ID   WP_033560344.1    Uniprot ID   -
Organism   Escherichia coli strain RIVM_C029494     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 783674..794333
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JNN66_RS03775 (JNN66_03775) - 784416..785363 (+) 948 WP_001296418.1 iron-siderophore ABC transporter substrate-binding protein -
  JNN66_RS03780 (JNN66_03780) - 785360..786247 (+) 888 WP_075862116.1 MurR/RpiR family transcriptional regulator -
  JNN66_RS03785 (JNN66_03785) ygiN 786292..786606 (-) 315 WP_000633738.1 putative quinol monooxygenase -
  JNN66_RS03790 (JNN66_03790) mdaB 786637..787218 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  JNN66_RS03795 (JNN66_03795) qseC 787328..788677 (-) 1350 WP_000673368.1 quorum sensing histidine kinase QseC -
  JNN66_RS03800 (JNN66_03800) ciaR 788674..789333 (-) 660 WP_033560344.1 quorum sensing response regulator transcription factor QseB Regulator
  JNN66_RS03805 (JNN66_03805) ygiW 789485..789877 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  JNN66_RS03810 (JNN66_03810) ygiV 789930..790412 (+) 483 WP_000183492.1 GyrI-like domain-containing protein -
  JNN66_RS03815 (JNN66_03815) ygiS 790521..792128 (+) 1608 WP_075862117.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24673.60 Da        Isoelectric Point: 6.9850

>NTDB_id=463283 JNN66_RS03800 WP_033560344.1 788674..789333(-) (ciaR) [Escherichia coli strain RIVM_C029494]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVVLDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=463283 JNN66_RS03800 WP_033560344.1 788674..789333(-) (ciaR) [Escherichia coli strain RIVM_C029494]
ATGCGAATTTTACTGATCGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGCGCACCTTATGATGCGGTGGTCCTGGATTTAACCT
TACCGGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTTTTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGCAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTTCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365