Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   HW271_RS08575 Genome accession   NZ_CP058258
Coordinates   1733404..1734702 (-) Length   432 a.a.
NCBI ID   WP_178895612.1    Uniprot ID   A0A7H8ZBR5
Organism   Streptococcus sp. oral taxon 061 strain F0704     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1728404..1739702
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HW271_RS08555 (HW271_08555) rplI 1729542..1729994 (-) 453 WP_178895608.1 50S ribosomal protein L9 -
  HW271_RS08560 (HW271_08560) - 1729991..1731901 (-) 1911 WP_398588224.1 DHH family phosphoesterase -
  HW271_RS08565 (HW271_08565) hpf 1732117..1732665 (-) 549 WP_178895610.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  HW271_RS08570 (HW271_08570) comFC/cflB 1732745..1733407 (-) 663 WP_178895611.1 ComF family protein Machinery gene
  HW271_RS08575 (HW271_08575) comFA/cflA 1733404..1734702 (-) 1299 WP_178895612.1 DEAD/DEAH box helicase Machinery gene
  HW271_RS08580 (HW271_08580) - 1734758..1735393 (+) 636 WP_178895613.1 YigZ family protein -
  HW271_RS08585 (HW271_08585) cysK 1735549..1736475 (+) 927 WP_178895614.1 cysteine synthase A -
  HW271_RS08590 (HW271_08590) - 1736599..1737947 (+) 1349 WP_178894523.1 IS3 family transposase -
  HW271_RS08595 (HW271_08595) tsf 1738003..1739043 (-) 1041 WP_049494452.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49660.80 Da        Isoelectric Point: 8.8664

>NTDB_id=463261 HW271_RS08575 WP_178895612.1 1733404..1734702(-) (comFA/cflA) [Streptococcus sp. oral taxon 061 strain F0704]
MKINPNYLGRLFTEQELSSEEQQLAEKLPSMRKEKGKLFCQRCDSMIQDEWSLPINAHYCRECLLMKRVRSDQGLYYFPQ
EKFPKQDVLKWKGQLTPFQEKVSEGLLQAVESQQPTLVHAVTGAGKTEMIYQVVAKVINDGGAVCLASPRIDVCLELYKR
LQNDFTCEIALLHGESKPYFRTPLVVATTHQLLKFYHAFDLLIVDEVDAFPYVDNRMLYKAVKNCVKDDGLRIFLTATST
DELDKKVRLGELKRLSLPRRFHGNPLIIPKPVWLSDLDKCLDKFRLPLKLKRYVENQRRTGYPLLIFASEITKGEKLKEI
LQLEFPNEKIGFVSSVTEDRLEQVQAFRDREMTILISTTILERGVTFPSVDVCVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGDLIFFHNGLNRSIKNAIKEIKLMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=463261 HW271_RS08575 WP_178895612.1 1733404..1734702(-) (comFA/cflA) [Streptococcus sp. oral taxon 061 strain F0704]
ATGAAAATAAATCCAAATTATCTTGGTCGACTTTTTACAGAACAAGAATTAAGCTCAGAAGAACAACAGTTGGCGGAGAA
GCTACCAAGCATGAGAAAAGAGAAGGGGAAACTCTTCTGTCAACGATGTGATAGTATGATTCAAGATGAATGGTCTCTAC
CTATTAATGCTCATTACTGCCGAGAATGCTTGTTGATGAAGCGAGTTAGGAGTGATCAAGGATTATATTATTTCCCTCAG
GAAAAATTTCCAAAACAAGATGTTCTTAAATGGAAGGGACAATTGACTCCATTTCAAGAGAAAGTATCAGAGGGATTACT
TCAAGCGGTAGAAAGTCAGCAGCCAACTTTAGTTCATGCAGTGACTGGCGCTGGGAAGACAGAGATGATTTATCAAGTTG
TTGCGAAAGTTATTAATGATGGTGGCGCAGTTTGTCTAGCCAGTCCCCGTATAGATGTTTGTTTGGAATTGTATAAGCGA
TTGCAGAATGATTTTACTTGTGAGATAGCCTTGCTGCATGGAGAGTCCAAACCATATTTTCGGACACCTCTGGTTGTTGC
GACGACTCATCAATTATTAAAGTTTTATCATGCTTTTGATTTGCTAATAGTAGATGAAGTAGATGCTTTTCCATATGTTG
ATAACAGGATGCTTTACAAAGCTGTAAAGAATTGTGTAAAGGATGATGGACTAAGAATTTTCCTCACCGCTACTTCTACA
GACGAGTTGGATAAGAAGGTTCGACTAGGGGAACTAAAACGACTAAGCCTACCAAGGCGGTTCCATGGGAATCCTTTAAT
TATTCCAAAACCCGTCTGGCTATCTGATCTGGATAAATGTTTGGATAAGTTTCGCCTACCATTAAAGTTAAAAAGATATG
TTGAAAACCAGAGAAGAACTGGCTACCCCTTACTAATATTTGCATCAGAAATTACAAAGGGAGAGAAGTTGAAGGAAATC
TTGCAGCTAGAGTTTCCGAATGAGAAAATTGGTTTCGTATCCTCAGTTACTGAAGATAGATTAGAGCAAGTTCAAGCTTT
TAGGGATAGGGAAATGACCATATTGATAAGCACAACAATATTGGAGCGCGGAGTTACCTTCCCTTCTGTTGATGTCTGTG
TCGTAGAAGCAAACCATCGTCTTTTTACAAAATCAAGTCTCATTCAAATTGGAGGACGTGTAGGTCGTAGCATGGATAGG
CCAACAGGAGATTTAATTTTCTTTCATAATGGATTAAACCGTTCGATTAAGAATGCTATAAAGGAAATCAAGCTGATGAA
CAAGGAGGCAGGCTTATGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-238)

Helicase conserved C-terminal domain (Helicase_C)

(291-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8ZBR5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

85.648

100

0.856
  comFA/cflA Streptococcus pneumoniae Rx1

85.648

100

0.856
  comFA/cflA Streptococcus pneumoniae D39

85.648

100

0.856
  comFA/cflA Streptococcus pneumoniae R6

85.648

100

0.856
  comFA/cflA Streptococcus pneumoniae TIGR4

85.417

100

0.854
  comFA/cflA Streptococcus mitis SK321

85.417

100

0.854
  comFA Lactococcus lactis subsp. cremoris KW2

52.261

92.13

0.481
  comFA Latilactobacillus sakei subsp. sakei 23K

38.695

99.306

0.384