Detailed information NTG0046271

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAPIG_RS14090
• Genome accession: NC_017333
• Coordinates: 2767714..2768601 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus subsp. aureus ST398
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2762714..2773601

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAPIG_RS14055	-	2762722..2762814 (+)	93	WP_031774855.1	hypothetical protein	-
SAPIG_RS14060 (SAPIG2669)	-	2762923..2763420 (-)	498	WP_001065267.1	glutathione peroxidase	-
SAPIG_RS14065	-	2763430..2763690 (-)	261	WP_014937088.1	hypothetical protein	-
SAPIG_RS14070	-	2764072..2764185 (-)	114	WP_014937089.1	hypothetical protein	-
SAPIG_RS14080 (SAPIG2671)	-	2764854..2766854 (-)	2001	WP_000776741.1	ABC transporter permease	-
SAPIG_RS14085 (SAPIG2672)	-	2766851..2767606 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
SAPIG_RS14090 (SAPIG2673)	braS	2767714..2768601 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAPIG_RS14095 (SAPIG2674)	braR	2768612..2769277 (-)	666	WP_000697874.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAPIG_RS14100 (SAPIG2675)	-	2769303..2769503 (-)	201	WP_000604731.1	hypothetical protein	-
SAPIG_RS14110 (SAPIG2676)	-	2769701..2771125 (+)	1425	WP_000953736.1	alkaline phosphatase	-
SAPIG_RS16080	-	2771185..2771286 (-)	102	WP_000731972.1	SE2200 family small protein	-
SAPIG_RS14115 (SAPIG2677)	-	2771408..2771863 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAPIG_RS14120 (SAPIG2678)	-	2772107..2772868 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=46271 SAPIG_RS14090 WP_000143420.1 2767714..2768601(-) (braS) [Staphylococcus aureus subsp. aureus ST398]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=46271 SAPIG_RS14090 WP_000143420.1 2767714..2768601(-) (braS) [Staphylococcus aureus subsp. aureus ST398]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTGGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993