Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JNN61_RS03825 Genome accession   NZ_CP068812
Coordinates   775725..776381 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain RIVM_C029020     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 770725..781381
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JNN61_RS03795 (JNN61_03795) yecA 771976..772641 (-) 666 WP_000847880.1 UPF0149 family protein YecA -
  JNN61_RS03815 (JNN61_03815) pgsA 773291..773839 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JNN61_RS03820 (JNN61_03820) uvrC 773896..775728 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JNN61_RS03825 (JNN61_03825) letA 775725..776381 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JNN61_RS25480 - 776523..776639 (+) 117 WP_023063716.1 hypothetical protein -
  JNN61_RS03830 (JNN61_03830) yecU 776677..776853 (+) 177 WP_000590344.1 protein YecU -
  JNN61_RS03835 (JNN61_03835) yecF 776840..777064 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  JNN61_RS03840 (JNN61_03840) sdiA 777131..777853 (-) 723 WP_001154265.1 transcriptional regulator SdiA -
  JNN61_RS03845 (JNN61_03845) tcyN 778083..778835 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JNN61_RS03850 (JNN61_03850) tcyL 778832..779500 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  JNN61_RS03855 (JNN61_03855) dcyD 779515..780501 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=462324 JNN61_RS03825 WP_000611328.1 775725..776381(-) (letA) [Escherichia coli strain RIVM_C029020]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=462324 JNN61_RS03825 WP_000611328.1 775725..776381(-) (letA) [Escherichia coli strain RIVM_C029020]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482