Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   JNN45_RS03490 Genome accession   NZ_CP068800
Coordinates   735507..736166 (-) Length   219 a.a.
NCBI ID   WP_106106579.1    Uniprot ID   -
Organism   Escherichia coli strain RIVM_C017997     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 730507..741166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JNN45_RS03465 (JNN45_03465) parE 730598..732490 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  JNN45_RS03470 (JNN45_03470) ygiN 732538..732852 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  JNN45_RS03475 (JNN45_03475) mdaB 732883..733464 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  JNN45_RS03480 (JNN45_03480) ygiZ 733783..734115 (+) 333 WP_000917684.1 DUF2645 family protein -
  JNN45_RS03485 (JNN45_03485) qseC 734161..735510 (-) 1350 WP_000673402.1 quorum sensing histidine kinase QseC -
  JNN45_RS03490 (JNN45_03490) ciaR 735507..736166 (-) 660 WP_106106579.1 quorum sensing response regulator transcription factor QseB Regulator
  JNN45_RS03495 (JNN45_03495) ygiW 736318..736710 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  JNN45_RS03500 (JNN45_03500) ygiV 736763..737245 (+) 483 WP_106106578.1 GyrI-like domain-containing protein -
  JNN45_RS03505 (JNN45_03505) mqsR 737450..737746 (+) 297 WP_000415583.1 type II toxin-antitoxin system toxin MqsR -
  JNN45_RS03510 (JNN45_03510) mqsA 737748..738143 (+) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  JNN45_RS03515 (JNN45_03515) ygiS 738276..739883 (+) 1608 WP_106106577.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24668.58 Da        Isoelectric Point: 6.7638

>NTDB_id=461325 JNN45_RS03490 WP_106106579.1 735507..736166(-) (ciaR) [Escherichia coli strain RIVM_C017997]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGHQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=461325 JNN45_RS03490 WP_106106579.1 735507..736166(-) (ciaR) [Escherichia coli strain RIVM_C017997]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCATCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGTT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365