Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   LILO_RS04435 Genome accession   NC_020450
Coordinates   907548..908177 (+) Length   209 a.a.
NCBI ID   WP_003131402.1    Uniprot ID   Q9CH48
Organism   Lactococcus lactis subsp. lactis IO-1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 902548..913177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LILO_RS04410 (lilo_0835) - 902836..904035 (+) 1200 WP_015426190.1 FtsW/RodA/SpoVE family cell cycle protein -
  LILO_RS04415 (lilo_0836) - 904066..905364 (+) 1299 WP_015426191.1 LCP family protein -
  LILO_RS04420 (lilo_0837) rpsN 905462..905731 (+) 270 WP_015426192.1 30S ribosomal protein S14 -
  LILO_RS04425 (lilo_0838) liaF 905896..906525 (+) 630 WP_015426193.1 cell wall-active antibiotics response protein LiaF -
  LILO_RS04430 (lilo_0839) - 906522..907520 (+) 999 WP_015426194.1 sensor histidine kinase -
  LILO_RS04435 (lilo_0840) vraR 907548..908177 (+) 630 WP_003131402.1 LuxR C-terminal-related transcriptional regulator Regulator
  LILO_RS04440 (lilo_0841) - 908248..909054 (+) 807 WP_015426195.1 Cof-type HAD-IIB family hydrolase -
  LILO_RS04445 (lilo_0842) - 909157..909747 (+) 591 WP_012897543.1 peptidylprolyl isomerase -
  LILO_RS04450 (lilo_0843) - 909749..910180 (+) 432 WP_015426196.1 CvfD/Ygs/GSP13 family RNA-binding post-transcriptional regulator -
  LILO_RS04455 (lilo_0845) - 910177..910782 (+) 606 WP_003131406.1 TVP38/TMEM64 family protein -
  LILO_RS04460 (lilo_0846) - 911004..912248 (+) 1245 WP_015426198.1 FtsW/RodA/SpoVE family cell cycle protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23204.85 Da        Isoelectric Point: 5.3572

>NTDB_id=46081 LILO_RS04435 WP_003131402.1 907548..908177(+) (vraR) [Lactococcus lactis subsp. lactis IO-1]
MEKIKLLIVDDHQMVRLGLSSFMNIQPDIEVVGEAADGESGFLKTEMLDPDVILMDLVMDRLDGIGATQKILAKNPERKI
LILTSFIDDEKVFPALAAGAKGYILKTSQAADIASAIRKVANGEDVLSDAVKEKIAQQKHRKHELYDDLSKRELEVLKVL
ATGLSNQEIADELFISLKTVKTHVSNIFNKLEVSDRTQATIYAIQHHLV

Nucleotide


Download         Length: 630 bp        

>NTDB_id=46081 LILO_RS04435 WP_003131402.1 907548..908177(+) (vraR) [Lactococcus lactis subsp. lactis IO-1]
ATGGAAAAAATTAAACTTTTAATTGTTGATGACCACCAGATGGTGCGACTAGGTTTATCAAGTTTCATGAATATTCAACC
CGATATCGAAGTGGTTGGTGAAGCTGCCGATGGCGAGTCAGGCTTTTTAAAAACTGAAATGCTTGACCCTGATGTTATTC
TTATGGATTTAGTGATGGATCGACTTGATGGAATTGGAGCAACGCAAAAGATTTTAGCCAAAAATCCAGAACGAAAAATT
TTAATTCTAACGAGTTTTATTGATGACGAAAAAGTTTTTCCGGCTTTAGCTGCTGGAGCTAAAGGTTATATTCTTAAAAC
ATCACAAGCCGCTGATATCGCATCTGCAATCAGAAAAGTTGCCAATGGAGAAGATGTCCTTTCCGATGCTGTCAAGGAAA
AGATTGCTCAACAAAAACATCGAAAACATGAATTATATGATGATTTATCAAAAAGAGAATTAGAAGTATTAAAAGTACTT
GCGACGGGACTTTCTAATCAAGAAATTGCTGACGAACTTTTTATCAGTTTAAAAACAGTCAAAACTCACGTTTCTAATAT
TTTTAATAAGCTTGAAGTGTCAGACCGAACTCAAGCAACAATTTATGCCATTCAACATCACTTAGTTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-117)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CH48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.565

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.416

Multiple sequence alignment