Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JKV47_RS14410 Genome accession   NZ_CP068680
Coordinates   3008235..3008891 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain NCCP12480     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3003235..3013891
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JKV47_RS14380 (JKV47_14270) dcyD 3004115..3005101 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  JKV47_RS14385 (JKV47_14275) tcyL 3005116..3005784 (+) 669 WP_001158218.1 cystine ABC transporter permease -
  JKV47_RS14390 (JKV47_14280) tcyN 3005781..3006533 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JKV47_RS14395 (JKV47_14285) sdiA 3006763..3007485 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  JKV47_RS14400 (JKV47_14290) yecF 3007552..3007776 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JKV47_RS14405 (JKV47_14295) yecU 3007763..3007939 (-) 177 WP_000590347.1 protein YecU -
  JKV47_RS22510 - 3008022..3008093 (-) 72 Protein_2808 transcriptional regulator -
  JKV47_RS14410 (JKV47_14300) letA 3008235..3008891 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JKV47_RS14415 (JKV47_14305) uvrC 3008888..3010720 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JKV47_RS14420 (JKV47_14310) pgsA 3010777..3011325 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JKV47_RS14440 (JKV47_14330) yecA 3011975..3012640 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=460645 JKV47_RS14410 WP_000611335.1 3008235..3008891(+) (letA) [Escherichia coli strain NCCP12480]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=460645 JKV47_RS14410 WP_000611335.1 3008235..3008891(+) (letA) [Escherichia coli strain NCCP12480]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486