Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   I6J13_RS09365 Genome accession   NZ_CP068213
Coordinates   84099..84920 (-) Length   273 a.a.
NCBI ID   WP_232565280.1    Uniprot ID   -
Organism   Streptococcus constellatus strain FDAARGOS_1156     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 79099..89920
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J13_RS00405 (I6J13_00405) - 79431..79805 (-) 375 WP_006270124.1 hypothetical protein -
  I6J13_RS00410 (I6J13_00410) comA/nlmT 80289..82439 (+) 2151 WP_006270130.1 peptide cleavage/export ABC transporter Regulator
  I6J13_RS00415 (I6J13_00415) - 82450..83811 (+) 1362 WP_006270117.1 bacteriocin secretion accessory protein -
  I6J13_RS00420 (I6J13_00420) - 83905..84054 (+) 150 WP_003025431.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  I6J13_RS09365 comD/blpH 84099..84920 (-) 822 WP_232565280.1 sensor histidine kinase Regulator
  I6J13_RS00430 (I6J13_00430) comE/blpR 85411..86157 (-) 747 WP_006270174.1 response regulator transcription factor Regulator
  I6J13_RS00435 (I6J13_00435) - 86326..87039 (-) 714 WP_006270152.1 CPBP family intramembrane glutamic endopeptidase -
  I6J13_RS00440 (I6J13_00440) - 87271..87492 (+) 222 WP_006267535.1 Blp family class II bacteriocin -
  I6J13_RS00445 (I6J13_00445) - 88169..88489 (+) 321 WP_006270150.1 hypothetical protein -
  I6J13_RS09540 - 88497..88715 (+) 219 Protein_90 garvicin Q family class II bacteriocin -
  I6J13_RS00450 (I6J13_00450) - 88782..89072 (+) 291 WP_006270118.1 bacteriocin immunity protein -
  I6J13_RS00455 (I6J13_00455) - 89222..89542 (+) 321 WP_006270149.1 hypothetical protein -

Sequence

Protein


Download         Length: 273 a.a.        Molecular weight: 31432.06 Da        Isoelectric Point: 6.2782

>NTDB_id=459189 I6J13_RS09365 WP_232565280.1 84099..84920(-) (comD/blpH) [Streptococcus constellatus strain FDAARGOS_1156]
MIVYHLIVQVLSYLENESNIQTLNFRESLVVLYLILFVSVANYLDRHLRERIQNDLMLQKDLQLKNMENYSHHIEELYTE
VRNFRHDYENILMTLKLGIEQNNLSIVKNVYHSVLKDSNKRFRNPKYDIGRLVHIKNEALKSLLAAKFAQAQEHNVAVSL
EVPEDIYPQGMELVDFITIVSILCDNAIEAAAPTMTIAYILSENKQVFSIENTIKEEHIDMSRIFDAGVSSKGAGRGIGL
SNVLAILDRYPNVSLTSASQNYRFQHVLEIHLN

Nucleotide


Download         Length: 822 bp        

>NTDB_id=459189 I6J13_RS09365 WP_232565280.1 84099..84920(-) (comD/blpH) [Streptococcus constellatus strain FDAARGOS_1156]
ATGATTGTTTATCATCTTATTGTTCAAGTTCTATCTTATTTAGAAAACGAGAGTAACATACAGACACTAAATTTTAGAGA
AAGTTTAGTAGTTCTTTATCTTATCCTTTTTGTGAGTGTTGCCAATTATTTAGACCGTCATTTACGAGAGAGAATCCAAA
ATGATTTAATGCTTCAAAAAGATTTACAGTTAAAAAATATGGAAAACTACAGTCATCACATTGAAGAACTGTACACAGAA
GTTCGGAATTTTCGGCATGATTACGAAAATATTTTAATGACCTTAAAATTAGGAATTGAACAAAATAATCTAAGTATTGT
AAAGAATGTCTATCATTCTGTTTTGAAAGATTCCAATAAGCGCTTTCGCAATCCCAAGTATGATATCGGACGGTTAGTCC
ATATCAAAAATGAAGCTTTAAAGAGCCTGCTAGCTGCTAAATTTGCACAAGCTCAAGAGCATAATGTAGCCGTTTCATTG
GAGGTTCCAGAAGATATTTACCCGCAAGGAATGGAATTAGTTGACTTTATCACCATTGTCTCCATTTTGTGTGATAATGC
TATTGAAGCTGCTGCTCCAACTATGACGATTGCTTATATTTTGTCAGAAAACAAGCAGGTATTCTCCATTGAAAATACTA
TAAAAGAGGAACATATAGACATGTCTCGTATTTTTGATGCAGGAGTTAGTTCTAAAGGAGCTGGGCGAGGAATTGGATTA
TCAAATGTCTTAGCAATTCTGGATAGGTACCCAAATGTTTCTCTTACTAGCGCTAGTCAAAATTATCGTTTCCAGCATGT
CCTTGAGATTCATCTGAATTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(171-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

43.066

100

0.432
  comD/comD3 Streptococcus equinus JB1

41.502

92.674

0.385
  comD/comD2 Streptococcus equinus JB1

38.043

100

0.385