Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   I6J15_RS04065 Genome accession   NZ_CP068056
Coordinates   784057..784746 (+) Length   229 a.a.
NCBI ID   WP_043895131.1    Uniprot ID   -
Organism   Streptococcus lutetiensis strain FDAARGOS_1158     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 779057..789746
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J15_RS04040 (I6J15_04040) - 779823..780767 (+) 945 WP_020917514.1 carbohydrate ABC transporter permease -
  I6J15_RS04045 (I6J15_04045) - 780767..781612 (+) 846 WP_020917513.1 carbohydrate ABC transporter permease -
  I6J15_RS04050 (I6J15_04050) - 781934..782125 (+) 192 WP_020917511.1 hypothetical protein -
  I6J15_RS04055 (I6J15_04055) bglS 782137..782778 (+) 642 WP_111713010.1 beta-glucanase -
  I6J15_RS04060 (I6J15_04060) - 782937..783731 (+) 795 WP_111713009.1 helix-turn-helix domain-containing protein -
  I6J15_RS04065 (I6J15_04065) ciaR 784057..784746 (+) 690 WP_043895131.1 response regulator transcription factor Regulator
  I6J15_RS04070 (I6J15_04070) - 784740..785900 (+) 1161 WP_164496881.1 sensor histidine kinase -
  I6J15_RS04075 (I6J15_04075) - 785910..786032 (+) 123 WP_111713008.1 teichoic acid D-Ala incorporation-associated protein DltX -
  I6J15_RS04080 (I6J15_04080) dltA 786048..787586 (+) 1539 WP_020917505.1 D-alanine--poly(phosphoribitol) ligase subunit DltA -
  I6J15_RS04085 (I6J15_04085) dltB 787583..788845 (+) 1263 WP_020917504.1 D-alanyl-lipoteichoic acid biosynthesis protein DltB -
  I6J15_RS04090 (I6J15_04090) dltC 788878..789117 (+) 240 WP_015695707.1 D-alanine--poly(phosphoribitol) ligase subunit DltC -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26086.40 Da        Isoelectric Point: 5.0608

>NTDB_id=458581 I6J15_RS04065 WP_043895131.1 784057..784746(+) (ciaR) [Streptococcus lutetiensis strain FDAARGOS_1158]
MRILVVEDEKGIAEAIQAILENHRYEVDLVFDGESALDYILTGLYDLVLLDIMLPKLDGVSVLKRVRQMGMEVPIIFLTA
KSQLEDRVLGLDLGADDYMIKPFEAEELLARIRLRTRQSSITQVNHLKFGNLILNLDTRELSVAEREVKLSNKEFLLMET
FLRNSKKIIPKNQLILKVWGPLDESDYNQLEVFISFLRKKLRFLAASAVIKTTKGVGYSLEDGEKEGSS

Nucleotide


Download         Length: 690 bp        

>NTDB_id=458581 I6J15_RS04065 WP_043895131.1 784057..784746(+) (ciaR) [Streptococcus lutetiensis strain FDAARGOS_1158]
TTGAGAATTTTAGTGGTCGAGGATGAGAAAGGAATTGCGGAAGCTATTCAAGCCATTCTTGAAAATCACCGTTATGAAGT
GGATTTGGTTTTTGATGGTGAGTCTGCACTGGATTATATATTAACGGGACTTTATGATTTGGTTCTTTTGGATATTATGT
TGCCAAAACTTGATGGTGTCAGTGTGTTGAAGCGCGTGCGCCAAATGGGAATGGAAGTTCCTATCATTTTTTTGACAGCC
AAATCTCAGTTAGAAGACCGTGTTTTGGGACTTGATTTGGGTGCTGATGACTATATGATTAAGCCATTTGAGGCAGAAGA
ATTATTGGCACGAATTCGTTTGCGGACTCGTCAATCGTCTATTACGCAAGTGAATCATCTCAAGTTTGGCAATTTGATTT
TGAATCTGGACACGAGAGAATTAAGCGTGGCAGAGCGCGAAGTTAAGTTGTCTAATAAAGAATTTCTGCTGATGGAAACT
TTCTTGCGAAATTCCAAGAAGATTATCCCCAAAAACCAATTAATTTTGAAGGTCTGGGGACCTTTAGATGAATCCGATTA
TAATCAACTGGAAGTCTTTATCTCCTTTTTACGTAAGAAACTTCGTTTCTTGGCAGCCAGTGCTGTTATTAAAACGACCA
AAGGCGTTGGTTACTCGCTAGAAGATGGAGAGAAAGAAGGCTCATCATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)

Response regulator receiver domain (Response_reg)

(3-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

39.64

96.943

0.384
  ciaR Streptococcus pneumoniae D39

39.64

96.943

0.384
  ciaR Streptococcus pneumoniae R6

39.64

96.943

0.384
  ciaR Streptococcus pneumoniae TIGR4

39.64

96.943

0.384
  ciaR Streptococcus mutans UA159

38.565

97.38

0.376