Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   I6J15_RS03595 Genome accession   NZ_CP068056
Coordinates   686774..688714 (+) Length   646 a.a.
NCBI ID   WP_020917598.1    Uniprot ID   A0AB33APE8
Organism   Streptococcus lutetiensis strain FDAARGOS_1158     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 681774..693714
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J15_RS03580 (I6J15_03580) argR 683313..683750 (+) 438 WP_020917601.1 arginine repressor -
  I6J15_RS03585 (I6J15_03585) - 683747..684100 (+) 354 WP_020917600.1 YlbF family regulator -
  I6J15_RS03590 (I6J15_03590) hexA 684087..686654 (+) 2568 WP_058814330.1 DNA mismatch repair protein MutS Machinery gene
  I6J15_RS03595 (I6J15_03595) hexB 686774..688714 (+) 1941 WP_020917598.1 DNA mismatch repair endonuclease MutL Machinery gene
  I6J15_RS03600 (I6J15_03600) ruvA 688715..689308 (+) 594 WP_020917597.1 Holliday junction branch migration protein RuvA Machinery gene
  I6J15_RS03605 (I6J15_03605) - 689338..689889 (+) 552 WP_058814328.1 DNA-3-methyladenine glycosylase I -
  I6J15_RS09020 - 690090..690317 (+) 228 WP_233422882.1 MFS transporter -
  I6J15_RS03615 (I6J15_03615) cinA 690792..692051 (+) 1260 WP_111713037.1 competence/damage-inducible protein A Machinery gene
  I6J15_RS03620 (I6J15_03620) recA 692098..693252 (+) 1155 WP_020917594.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 646 a.a.        Molecular weight: 73143.38 Da        Isoelectric Point: 5.3658

>NTDB_id=458575 I6J15_RS03595 WP_020917598.1 686774..688714(+) (hexB) [Streptococcus lutetiensis strain FDAARGOS_1158]
MSKIIELPEVLANQIAAGEVVERPASVVKELVENSIDAGSSQITIEIEESGLKKIQVTDNGEGISQEDVALSLHRHATSK
IKSQADLFRIRTLGFRGEAIPSIASISHFTVKTATADEHYGMLLVAKGGEIERQEPISTPVGTKITVENLFYNTPARLKY
MKSLQSELAHIVDVVNRLSLAHPEIAFTLINDGHQMTTTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEIRISKEKELMSLISS
AIAESLREQDLIPDALENLAKSSTRGLPKPQQTSLPLKQTNFYYDKERHDFFVKSDTVEEEPVQLFNEVDKGVNPVDKQS
SVRYAQRSAADQEYDEHDSLDFKNKTKINRMIESLDKEEISTFPELEYFGQMHGTYLFAQGNGGLYIIDQHAAQERIKYE
YYRDKIGEVDDSLQQLLMPYLFEFSGADFIKLQEKMELLKQVGINLEPYGNNTFILREHPIWMKEGEIETAVYEMCDMLL
LTNEVSVKKYCAELAIMMSCKRSIKANHTLDDYSARQLIVQLSQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTSL
RELGKY

Nucleotide


Download         Length: 1941 bp        

>NTDB_id=458575 I6J15_RS03595 WP_020917598.1 686774..688714(+) (hexB) [Streptococcus lutetiensis strain FDAARGOS_1158]
ATGAGTAAAATTATTGAGTTGCCAGAGGTTTTGGCCAACCAGATTGCTGCAGGTGAAGTTGTTGAACGACCAGCTAGTGT
GGTTAAAGAATTGGTTGAAAATTCGATTGATGCTGGAAGTAGTCAGATTACCATCGAGATTGAAGAATCAGGTCTTAAGA
AGATTCAAGTCACTGATAATGGTGAGGGAATTTCTCAAGAGGATGTAGCGTTGAGTTTGCATCGTCATGCTACAAGTAAG
ATTAAAAGCCAAGCAGACCTTTTTCGTATCAGAACTTTGGGATTTCGCGGTGAGGCCATCCCTTCCATTGCCTCAATTAG
CCATTTCACAGTGAAAACAGCGACTGCTGATGAACACTACGGAATGCTTTTAGTGGCAAAAGGGGGCGAGATTGAGCGAC
AAGAACCAATTTCAACGCCTGTCGGGACAAAAATTACCGTTGAAAATCTTTTTTACAACACTCCTGCTCGTCTTAAGTAC
ATGAAAAGCTTGCAATCAGAGTTGGCTCATATCGTTGATGTGGTTAATCGCTTGAGCCTAGCTCATCCAGAAATTGCCTT
TACTTTGATTAATGATGGTCATCAAATGACAACGACTTCTGGGACAGGTGATTTGCGTCAAGCCATTGCTGGTATTTACG
GTTTAAATACAGCTAAGAAAATGATTGAAATCTCAAATGCCGACCTTGATTTTGAAGTGTCAGGTTATATTAGCTTACCA
GAATTGACGCGTGCCAATCGCAATTACATTACTATTTTAATCAATGGTCGCTACATCAAAAATTTCTTGCTCAACCGTGC
GATTTTGGATGGTTACGGGTCAAAATTGATGGTTGGTCGCTTCCCAATTGCTGTCATCGATATTCAAATCGATCCTTACC
TTGCTGATGTTAATGTCCACCCAACCAAGCAAGAAATTCGTATCTCAAAAGAAAAAGAACTCATGAGCTTAATCAGTTCA
GCTATTGCAGAGAGTTTGCGTGAGCAAGATTTGATTCCAGATGCTCTTGAAAATCTAGCTAAGTCAAGTACACGAGGTCT
TCCAAAACCCCAGCAAACGAGTCTGCCTTTAAAACAAACCAACTTTTACTATGATAAGGAACGTCACGATTTCTTTGTGA
AATCAGATACGGTTGAAGAAGAGCCAGTGCAGTTGTTTAATGAGGTTGACAAAGGTGTCAATCCAGTTGACAAGCAATCT
TCGGTTAGGTATGCACAGCGTTCAGCGGCAGATCAAGAGTATGATGAGCATGATAGTCTTGATTTTAAAAATAAAACGAA
AATCAATCGTATGATTGAAAGTCTTGATAAGGAGGAAATCTCTACTTTCCCTGAGTTAGAGTACTTTGGGCAAATGCACG
GTACTTATCTTTTTGCACAAGGTAATGGTGGGCTTTATATCATTGACCAGCATGCGGCGCAGGAACGTATCAAGTATGAG
TATTATCGTGACAAAATTGGCGAAGTTGATGACTCATTACAACAGTTGCTGATGCCATATCTGTTTGAATTTTCTGGGGC
AGATTTCATCAAACTTCAAGAAAAAATGGAGCTTCTAAAGCAAGTTGGTATTAATTTAGAACCATACGGCAATAACACTT
TTATCCTTCGTGAGCATCCTATTTGGATGAAGGAAGGGGAGATTGAGACAGCTGTTTATGAAATGTGCGACATGTTACTG
TTGACCAATGAAGTTTCTGTCAAGAAATACTGTGCTGAGTTAGCGATTATGATGTCATGTAAACGATCAATCAAGGCTAA
CCATACCCTTGATGACTATTCAGCCCGACAACTCATCGTTCAATTATCACAATGTAAGAATCCTTATAACTGCCCACACG
GACGTCCAGTGCTTGTTAATTTCACCAAGTCAGACATGGAAAAGATGTTCCGTCGTATTCAAGAAAATCATACAAGTTTA
AGAGAGTTAGGAAAATACTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(448-590)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AB33APE8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.313

100

0.703