Detailed information NTG0458574

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: I6J15_RS03590
• Genome accession: NZ_CP068056
• Coordinates: 684087..686654 (+)
• Length: 855 a.a.
• NCBI ID: WP_058814330.1
• Uniprot ID: -
• Organism: Streptococcus lutetiensis strain FDAARGOS_1158
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 679087..691654

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J15_RS03570 (I6J15_03570)	-	679966..681384 (+)	1419	WP_111699143.1	prolyl oligopeptidase family serine peptidase	-
I6J15_RS03575 (I6J15_03575)	argS	681432..683123 (-)	1692	WP_111713039.1	arginine--tRNA ligase	-
I6J15_RS03580 (I6J15_03580)	argR	683313..683750 (+)	438	WP_020917601.1	arginine repressor	-
I6J15_RS03585 (I6J15_03585)	-	683747..684100 (+)	354	WP_020917600.1	YlbF family regulator	-
I6J15_RS03590 (I6J15_03590)	hexA	684087..686654 (+)	2568	WP_058814330.1	DNA mismatch repair protein MutS	Machinery gene
I6J15_RS03595 (I6J15_03595)	hexB	686774..688714 (+)	1941	WP_020917598.1	DNA mismatch repair endonuclease MutL	Machinery gene
I6J15_RS03600 (I6J15_03600)	ruvA	688715..689308 (+)	594	WP_020917597.1	Holliday junction branch migration protein RuvA	Machinery gene
I6J15_RS03605 (I6J15_03605)	-	689338..689889 (+)	552	WP_058814328.1	DNA-3-methyladenine glycosylase I	-
I6J15_RS09020	-	690090..690317 (+)	228	WP_233422882.1	MFS transporter	-

Sequence

Protein

• Length: 855 a.a.
• Molecular weight: 95902.06 Da
• Isoelectric Point: 4.9508

>NTDB_id=458574 I6J15_RS03590 WP_058814330.1 684087..686654(+) (hexA) [Streptococcus lutetiensis strain FDAARGOS_1158]
MAKDKISPGMQQYLDVKKDYPEAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVIQVITPGTAVDSSKPDNANNFLVAIDSDGKTFGLAYMDVSTGEFYATSLSDFTS
LKSEILNLKAREIVVGYDLSEDEQHSLVKQLNLLLSFEQERYEDVHLIDPNLTALEISAAEKLLQYVHTTQKRELSHLQK
LVHYEIKDYLQMSYTTKSSLDLLENARTSKKHGSLYWLLDETKTAMGMRLLRNWIDRPLVNQEQIEERQNIIQVFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLGQVPTIKAILESFDSPYLDKLVNSIDTLPELKSLISSAIDS
DAQAVITEGSIIRTGFDETLDKYRKVMREGTSWIAEIEAKERAASGITNLKIDYNKKDGYYFHVTNSNLSLVPDYFFRKA
TLKNSERFGTAELAKIEGEMLEAHEQSASLEYDIFMRVRAQVERYISRLQDLAKAISTVDVLQSLAVVAENNHYVRPTFN
NNHEIKIDKGRHAVVEKVMGTQEYIPNTITFGRNTNIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAAESVSLPVFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASEKSLILFDELGRGTATYDGMALAQSIIEYIHDHIGAKTMFATHYHEL
TSLSTTLTHLVNVHVATLERNGDVTFLHKIAEGPADKSYGIHVAKIAGLPEDLLQRAGSILTNLESGAAQLHLTAETEEK
TQVKTEAAEPVAEQLSLFADDSSNQEVIEALKKVDLMNLTPMQAMNVIYELKNML

Nucleotide

• Length: 2568 bp

>NTDB_id=458574 I6J15_RS03590 WP_058814330.1 684087..686654(+) (hexA) [Streptococcus lutetiensis strain FDAARGOS_1158]
ATGGCAAAAGATAAAATTTCTCCAGGCATGCAACAGTATTTGGATGTCAAAAAAGACTATCCAGAGGCTTTTTTACTTTT
CCGCATGGGAGACTTTTACGAACTATTTTATGATGACGCCGTTAAGGCGGCACAGATTTTAGAGATTAGTTTAACTAGTC
GTAATAAAAATGCTGACAATCCTATTCCGATGGCTGGTGTTCCTTATCATTCAGCCCAACAATACATTGATGTCTTGGTT
GAGATGGGGTATAAGGTTGCCATTGCTGAGCAGATGGAAGATCCGAAGCAGGCAGTGGGTGTGGTTAAGCGTGAAGTCAT
TCAGGTTATTACACCAGGGACAGCGGTTGATTCTTCTAAGCCAGATAATGCTAATAATTTCTTGGTAGCCATCGATTCAG
ATGGTAAAACTTTTGGTTTGGCATACATGGATGTGTCAACGGGTGAGTTTTACGCGACAAGTTTGTCTGATTTTACAAGC
CTAAAAAGTGAGATTTTAAATCTCAAGGCTCGTGAAATCGTGGTTGGTTATGACCTTTCTGAAGATGAGCAACACAGCTT
GGTTAAACAACTCAATCTCTTATTATCGTTTGAGCAAGAGCGCTATGAAGATGTGCATTTGATTGACCCTAATTTAACAG
CGTTAGAGATTTCTGCTGCTGAAAAATTACTTCAATACGTTCACACAACACAAAAACGTGAACTTAGTCACTTGCAAAAG
CTTGTTCACTATGAAATCAAAGACTATCTTCAAATGTCTTATACGACAAAATCAAGTCTTGATTTGCTAGAAAATGCCCG
TACTAGCAAGAAACACGGTAGTCTTTATTGGTTGCTTGATGAGACTAAAACTGCCATGGGGATGCGTTTGTTGCGTAACT
GGATTGATCGTCCATTGGTTAACCAAGAACAAATTGAAGAACGTCAAAATATTATTCAAGTTTTCTTAGACAACTTCTTT
GAACGTAGTGATTTGACGGACAGTCTAAAAGGTGTCTATGATATTGAACGTTTGGCTAGTCGCGTGTCATTTGGAAAAGC
CAATCCAAAAGATTTGCTTCAACTTGGTCACACTTTGGGGCAAGTGCCAACGATTAAAGCTATCTTGGAGTCTTTTGATA
GTCCGTACCTTGACAAGCTTGTCAACAGCATTGACACTTTACCAGAGCTAAAGTCATTGATTAGCTCTGCTATTGATTCA
GATGCTCAAGCGGTGATTACGGAAGGAAGTATTATCAGAACTGGTTTTGATGAGACTTTGGACAAATACCGTAAAGTCAT
GCGCGAAGGGACAAGCTGGATTGCTGAGATTGAAGCTAAAGAACGTGCGGCAAGTGGCATTACCAATCTAAAAATTGATT
ACAATAAAAAAGATGGCTATTATTTCCATGTCACAAATTCTAACCTTTCTTTGGTGCCAGATTACTTCTTCCGTAAAGCA
ACTTTGAAGAATTCAGAGCGTTTTGGTACAGCAGAATTGGCTAAAATTGAAGGTGAAATGCTAGAAGCGCATGAGCAATC
AGCGAGTCTGGAATACGATATTTTCATGCGTGTTCGCGCACAGGTGGAACGTTATATTTCACGTCTGCAAGATTTGGCAA
AAGCTATTTCTACAGTCGATGTTCTGCAAAGTTTGGCAGTGGTTGCGGAAAATAATCATTACGTGCGTCCAACTTTCAAC
AATAATCATGAAATTAAGATTGATAAAGGTCGCCATGCAGTTGTTGAAAAAGTCATGGGCACGCAAGAGTATATTCCAAA
TACCATTACATTTGGCAGAAATACCAATATTCAGCTGATTACTGGTCCAAATATGAGTGGTAAATCAACTTATATGCGTC
AGTTAGCTTTGACGGTTATCATGGCACAGATGGGGTCATACGTTGCTGCTGAGAGTGTTAGTCTTCCAGTTTTTGATGCG
ATTTTCACACGTATCGGTGCGGCGGATGATTTGATTTCAGGTCAGTCAACCTTCATGGTGGAAATGATGGAAGCCAACCA
AGCCATTAAACGTGCTAGTGAAAAATCTTTGATTCTCTTTGATGAATTGGGACGCGGGACAGCGACTTATGATGGAATGG
CTTTAGCACAATCTATCATTGAGTATATCCATGATCACATTGGTGCTAAGACCATGTTTGCGACTCACTATCATGAATTG
ACATCTCTGTCAACTACCTTGACACATCTTGTAAACGTCCATGTTGCAACGCTTGAACGTAATGGTGATGTGACTTTTCT
TCATAAAATCGCAGAAGGACCAGCTGACAAATCTTATGGTATTCACGTTGCGAAAATTGCAGGTTTGCCAGAAGATTTGT
TGCAACGAGCAGGTAGTATTTTAACCAATCTCGAATCAGGTGCTGCGCAGCTTCATTTGACAGCAGAAACTGAAGAGAAA
ACTCAAGTGAAGACAGAAGCGGCAGAACCTGTTGCAGAGCAGCTTAGCTTATTTGCAGATGACTCAAGTAACCAAGAAGT
GATTGAAGCTCTTAAAAAAGTGGACTTGATGAATCTAACACCAATGCAAGCCATGAATGTCATTTATGAATTGAAAAACA
TGTTATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (256-546)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	72.047	100	0.72
mutS	Pseudomonas stutzeri strain ATCC 17587	37.228	100	0.38