Detailed information NTG0458273

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: JJN14_RS09365
• Genome accession: NZ_CP067992
• Coordinates: 1899074..1901608 (-)
• Length: 844 a.a.
• NCBI ID: WP_201058510.1
• Uniprot ID: -
• Organism: Streptococcus mitis strain S022-V7-A3
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1894074..1906608

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JJN14_RS09335 (JJN14_09335)	-	1894340..1894603 (+)	264	WP_000166114.1	SemiSWEET family transporter	-
JJN14_RS09340 (JJN14_09340)	-	1894688..1895251 (-)	564	WP_201058506.1	DNA-3-methyladenine glycosylase I	-
JJN14_RS09345 (JJN14_09345)	ruvA	1895261..1895854 (-)	594	WP_084862868.1	Holliday junction branch migration protein RuvA	Machinery gene
JJN14_RS09350 (JJN14_09350)	hexB	1895983..1897932 (-)	1950	WP_201058507.1	DNA mismatch repair endonuclease MutL	Machinery gene
JJN14_RS09355 (JJN14_09355)	-	1898137..1898577 (+)	441	WP_201058508.1	LytTR family DNA-binding domain-containing protein	-
JJN14_RS09360 (JJN14_09360)	-	1898574..1899032 (+)	459	WP_201058509.1	DUF3021 domain-containing protein	-
JJN14_RS09365 (JJN14_09365)	hexA	1899074..1901608 (-)	2535	WP_201058510.1	DNA mismatch repair protein MutS	Machinery gene
JJN14_RS09370 (JJN14_09370)	argR	1901659..1902105 (-)	447	WP_001231476.1	arginine repressor	-
JJN14_RS09375 (JJN14_09375)	argS	1902241..1903932 (+)	1692	WP_201058511.1	arginine--tRNA ligase	-
JJN14_RS09380 (JJN14_09380)	-	1904502..1904747 (+)	246	WP_042751768.1	hypothetical protein	-
JJN14_RS09385 (JJN14_09385)	nrdI	1904914..1905378 (-)	465	WP_020901834.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
JJN14_RS09390 (JJN14_09390)	-	1905452..1905985 (-)	534	WP_049487383.1	hypothetical protein	-

Sequence

Protein

• Length: 844 a.a.
• Molecular weight: 94699.96 Da
• Isoelectric Point: 4.8587

>NTDB_id=458273 JJN14_RS09365 WP_201058510.1 1899074..1901608(-) (hexA) [Streptococcus mitis strain S022-V7-A3]
MATEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLI
EQGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKEGFEDLHLLDSRLATVEQAASSKLLQYVHRTQMRELNHLKP
VIRYEIKDYLQMDYATKASLDLVENARSGKKQGSLFWLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFF
ERSDLTDSLKGVYDIERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIEQLDGIPELESLISAAIAP
EAPHVITEGGIIRTGFDETLDKYRRVLREGTGWIAEIEAKERENSGISTLKIDYNKKDGYYFHVTNSQLGNVPAHFFRKA
TLKNSERFGTEELARIEGDMLEAREKSANLEYEIFMRIREEVSKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFG
DDSQIDIQKGRHAVVEKVMGAQTYIPNTIQMAEDSSIQLITGPNMSGKSTYMRQLAMTAVMAQLGSYVPAESAHLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDELGRGTATYDGMAIAQSIIEYIHEHIGAKTLFATHYHEL
TSLESSLEHLVNVHVATLEQDGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLTRADKILTQLESQGTESPAPMRQTSA
VTEQISLFDTAEEHPVLAELSKLDVYNMTPMQAMNVLVELKQKL

Nucleotide

• Length: 2535 bp

>NTDB_id=458273 JJN14_RS09365 WP_201058510.1 1899074..1901608(-) (hexA) [Streptococcus mitis strain S022-V7-A3]
ATGGCGACAGAAAAGCTATCACCCGGCATGCAACAGTATGTGGATATTAAAAAGCAATATCCAGATGCTTTTTTGCTCTT
TCGGATGGGTGATTTTTATGAATTGTTTTATGAGGATGCGGTCAATGCTGCGCAGATTCTGGAAATTTCCTTAACGAGTC
GCAACAAGAATGCGGATAACCCGATTCCTATGGCGGGGGTTCCTTATCATTCTGCCCAACAGTACATCGATGTCTTGATT
GAGCAGGGCTATAAGGTAGCCATTGCTGAACAGATGGAAGATCCTAAACAAGCAGTTGGGGTTGTAAAACGAGAGGTTGT
TCAGGTTATTACGCCAGGGACAGTAGTCGATAGCAGTAAGCCGGATAGTCAGAATAATTTTTTGGTTGCCATAGACCGCG
AAGGCAATCAATTCGGCCTAGCTTATATGGACCTGGTGACGGGTGACTTTTATGTGACAGGTCTTTTGGATTTTACGCTT
GTTTGTGGGGAAATCCGCAATCTCAAGGCTCGAGAAGTGGTGCTGGGTTATGACTTGTCTGAGGAAGAGGAACAAATTCT
CAGTCGTCAGATGAATCTGGTGCTTTCCTATGAAAAAGAAGGCTTTGAGGACCTTCATTTACTGGATTCACGATTGGCAA
CTGTGGAGCAAGCGGCCTCTAGTAAGCTCCTCCAGTATGTCCATCGAACCCAGATGAGGGAATTGAACCACCTCAAGCCT
GTTATCCGCTATGAAATCAAAGATTACTTGCAGATGGATTATGCGACCAAGGCTAGTCTGGATCTGGTTGAGAATGCTCG
GTCAGGCAAGAAGCAAGGCAGTCTTTTCTGGCTTTTGGATGAAACCAAAACAGCTATGGGTATGCGGCTCTTGCGTTCTT
GGATTCATCGTCCTTTGATTGATAAGGAACGAATCGTCCAACGCCAAGAAGTGGTGCAGGTCTTTCTCGACCATTTCTTT
GAGCGTAGTGATTTGACAGACAGTCTCAAGGGAGTTTATGATATCGAACGCTTGGCTAGTCGGGTTTCTTTTGGCAAAAC
CAATCCCAAGGATCTCTTGCAGTTGGCGACCACCTTGTCCAGTGTGCCACGGATTCGTGCGATTTTAGAAGGGATGGAGC
AACCTGCTCTGGCTTATCTTATCGAACAATTAGATGGAATCCCTGAGTTGGAGAGTTTGATTAGCGCAGCGATTGCTCCT
GAAGCTCCTCATGTGATTACGGAAGGTGGCATTATCCGCACTGGATTTGATGAAACCTTAGACAAGTACCGTCGTGTGCT
CAGAGAAGGGACTGGTTGGATTGCTGAGATTGAGGCTAAGGAACGCGAAAACTCTGGTATCAGCACGCTTAAGATTGACT
ACAATAAAAAGGATGGCTACTATTTCCATGTAACCAATTCACAACTGGGAAATGTGCCAGCTCACTTTTTCCGCAAGGCA
ACGCTGAAAAACTCGGAACGTTTTGGAACTGAGGAATTAGCGCGTATCGAGGGAGATATGCTGGAGGCGCGTGAGAAGTC
AGCCAACCTAGAGTATGAAATCTTTATGCGTATCCGTGAGGAAGTCAGCAAGTACATTCAGCGTTTGCAGGCTCTAGCTC
AAGGGATTGCGACAGTTGATGTCTTACAAAGCTTGGCAGTTGTAGCTGAAACCCAGCATTTGATTCGACCAGAGTTCGGA
GACGATTCGCAGATCGATATCCAGAAAGGGCGCCATGCTGTCGTTGAAAAGGTTATGGGGGCTCAGACCTATATTCCAAA
TACGATTCAGATGGCAGAAGATAGCAGTATTCAACTGATTACAGGGCCAAACATGAGTGGGAAGTCAACCTACATGCGTC
AGTTAGCCATGACGGCGGTGATGGCCCAGCTGGGTTCTTATGTGCCAGCAGAAAGCGCCCATTTGCCGATTTTTGATGCG
ATTTTTACCCGTATCGGAGCAGCCGATGATTTGGTTTCAGGTCAGTCAACCTTTATGGTGGAGATGATGGAGGCCAACAA
TGCCATTTCGCATGCGACTAAGAATTCTTTGATTCTCTTTGATGAGTTAGGTCGGGGAACTGCTACTTATGACGGGATGG
CTATTGCACAGTCCATTATTGAATACATCCATGAGCATATCGGAGCCAAGACTCTCTTTGCGACCCACTACCATGAGTTG
ACCAGTCTAGAGTCTAGCTTGGAACACTTGGTCAATGTCCACGTGGCAACCTTGGAGCAGGATGGGCAGGTTACCTTCCT
TCACAAGATTGAACCAGGTCCAGCTGATAAGTCCTATGGTATCCATGTTGCCAAGATTGCTGGTTTGCCAGCAGACCTTT
TAACAAGGGCGGATAAGATTTTGACCCAACTGGAGAGTCAGGGGACAGAAAGTCCTGCTCCAATGAGGCAAACAAGTGCT
GTCACTGAACAGATTTCACTCTTTGATACGGCAGAAGAGCATCCTGTCCTAGCAGAATTGTCTAAACTGGATGTTTACAA
TATGACACCTATGCAGGCTATGAATGTCTTGGTTGAGTTAAAACAAAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain III (MutS_III) (256-546)

• MutS domain II (MutS_II) (126-239)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	97.038	100	0.97
mutS	Pseudomonas stutzeri strain ATCC 17587	36.534	100	0.37