Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   JJN14_RS09350 Genome accession   NZ_CP067992
Coordinates   1895983..1897932 (-) Length   649 a.a.
NCBI ID   WP_201058507.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V7-A3     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1890983..1902932
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJN14_RS09325 (JJN14_09325) - 1891777..1893033 (+) 1257 WP_201058285.1 ISL3 family transposase -
  JJN14_RS09330 (JJN14_09330) - 1893200..1894234 (+) 1035 WP_201058505.1 S66 family peptidase -
  JJN14_RS09335 (JJN14_09335) - 1894340..1894603 (+) 264 WP_000166114.1 SemiSWEET family transporter -
  JJN14_RS09340 (JJN14_09340) - 1894688..1895251 (-) 564 WP_201058506.1 DNA-3-methyladenine glycosylase I -
  JJN14_RS09345 (JJN14_09345) ruvA 1895261..1895854 (-) 594 WP_084862868.1 Holliday junction branch migration protein RuvA Machinery gene
  JJN14_RS09350 (JJN14_09350) hexB 1895983..1897932 (-) 1950 WP_201058507.1 DNA mismatch repair endonuclease MutL Machinery gene
  JJN14_RS09355 (JJN14_09355) - 1898137..1898577 (+) 441 WP_201058508.1 LytTR family DNA-binding domain-containing protein -
  JJN14_RS09360 (JJN14_09360) - 1898574..1899032 (+) 459 WP_201058509.1 DUF3021 domain-containing protein -
  JJN14_RS09365 (JJN14_09365) hexA 1899074..1901608 (-) 2535 WP_201058510.1 DNA mismatch repair protein MutS Machinery gene
  JJN14_RS09370 (JJN14_09370) argR 1901659..1902105 (-) 447 WP_001231476.1 arginine repressor -

Sequence

Protein


Download         Length: 649 a.a.        Molecular weight: 73418.87 Da        Isoelectric Point: 5.3017

>NTDB_id=458272 JJN14_RS09350 WP_201058507.1 1895983..1897932(-) (hexB) [Streptococcus mitis strain S022-V7-A3]
MSHIIELPEVLANQIAAGEVIERPASVVKELVENAIDAGSSQIIIEIEEAGLKKIQITDNGHGIAHDEVELALRRHATSK
IKNQADLFRIRTLGFRGEALPSIASVSVLTLLTAVEGASHGTKLVARGGEVEEIIPATSPVGTKVCVEDLFFNTPARLKY
MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSAKKMIEIENSDLDFEISGFVSLP
ELTRANRNYISLFINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSE
AIANSLKEQTLIPDALENLAKSTVRNREKVEQTILPLKENTLYYEKSEPTRPSQAEVADYQVELTDEGQDLTLFAKETLD
QLTKPAKLHFAERKPANYDQLDHPELDLASLDKAYDKLEREESSSFPELEFFGQMHGTYLFAQGRDGLYIIDQHAAQERV
KYEEYRESIGNVDQSQQQLLVPYIFEFPADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCD
MLLLTKEVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSKCDNPYNCPHGRPVLVHFTKSDMEKMFRRIQENH
TSLRELGKY

Nucleotide


Download         Length: 1950 bp        

>NTDB_id=458272 JJN14_RS09350 WP_201058507.1 1895983..1897932(-) (hexB) [Streptococcus mitis strain S022-V7-A3]
ATGTCTCATATTATTGAATTACCAGAGGTGCTGGCAAACCAGATTGCGGCTGGAGAGGTTATCGAGCGTCCAGCTAGCGT
TGTTAAGGAGCTGGTAGAAAATGCCATTGACGCGGGTTCTAGTCAGATTATCATTGAGATTGAGGAAGCTGGTCTCAAGA
AGATTCAAATCACAGATAATGGTCATGGAATTGCCCACGATGAGGTGGAGTTAGCCCTTCGTCGTCATGCGACCAGTAAG
ATAAAAAATCAAGCGGATCTTTTTCGGATTCGTACTTTGGGTTTTCGTGGTGAAGCCCTGCCCTCTATCGCATCCGTCAG
CGTTTTAACTCTTTTGACAGCAGTTGAGGGCGCAAGTCACGGGACCAAGCTGGTCGCGCGTGGGGGAGAAGTAGAGGAAA
TCATCCCAGCGACCAGTCCTGTGGGAACCAAGGTTTGTGTGGAGGACCTTTTTTTCAACACGCCTGCCCGCCTCAAGTAT
ATGAAGAGCCAGCAAGCAGAGTTGTCTCATATCATTGATATTGTCAACCGTCTGGGTTTGGCCCATCCTGAGATTTCTTT
TAGTTTGATTAGTGATGGTAAGGAAATGACACGAACAGCGGGAACAGGTCAATTGCGCCAAGCTATCGCAGGGATTTACG
GTTTGGTGAGTGCCAAGAAGATGATTGAAATTGAGAATTCTGACCTTGATTTCGAAATTTCTGGCTTTGTATCCTTGCCT
GAGTTAACTAGAGCCAATCGTAATTATATCAGTCTCTTCATCAATGGCCGTTATATCAAGAACTTCCTACTCAATCGTGC
TATTTTGGATGGTTACGGAAGCAAGCTCATGGTAGGCCGTTTTCCGCTGGCTGTCATTCACATCCATATCGATCCTTATC
TAGCGGATGTCAATGTGCATCCAACCAAGCAAGAGGTGCGGATTTCCAAGGAAAAAGAACTGATGACCCTGGTTTCAGAA
GCAATTGCAAATAGTCTCAAGGAACAAACCTTGATTCCAGATGCCTTGGAAAATCTTGCCAAATCGACTGTGCGCAATCG
TGAGAAGGTGGAGCAGACCATTCTCCCGCTTAAAGAAAATACCCTCTACTATGAGAAAAGTGAGCCGACAAGACCTAGTC
AAGCTGAGGTGGCTGATTATCAGGTTGAATTAACTGATGAAGGACAGGATTTAACCCTGTTTGCCAAAGAAACCTTGGAC
CAATTGACTAAGCCAGCAAAATTGCATTTTGCAGAGAGAAAACCTGCTAACTATGACCAATTAGACCATCCAGAGTTAGA
TCTAGCTAGCCTCGATAAGGCTTATGATAAGCTAGAGCGAGAAGAATCTTCAAGTTTCCCAGAGTTGGAATTTTTCGGGC
AAATGCACGGGACTTATCTCTTTGCCCAAGGACGAGATGGGCTCTACATCATAGACCAACATGCAGCTCAGGAACGGGTC
AAGTATGAGGAATATCGTGAAAGCATTGGCAATGTTGACCAGAGCCAGCAGCAACTCCTAGTGCCCTATATCTTTGAATT
TCCAGCGGATGATGCCCTTCGTCTCAAGGAAAGAATGCCTCTTTTAGAGGAAGTTGGGGTCTTTCTAGCAGAGTACGGGG
AAAATCAATTCATCCTACGTGAACATCCTATTTGGATGGCAGAGGAGGAAATCGAGTCAGGCATCTATGAAATGTGCGAC
ATGCTCCTCTTGACCAAGGAGGTTTCTATCAAGAAATACCGTGCAGAGTTGGCTATTATGATGTCCTGCAAACGGTCTAT
CAAGGCCAACCATCGTATTGACGATCATTCGGCTAGACAGCTTCTTTATCAACTTTCTAAATGTGACAATCCCTATAACT
GTCCTCACGGACGTCCTGTTTTGGTGCATTTTACCAAGTCAGATATGGAAAAGATGTTCCGACGCATTCAGGAAAATCAT
ACCAGTCTTCGTGAGTTGGGGAAATATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(450-592)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-117)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

98.151

100

0.982