Detailed information    

insolico Bioinformatically predicted

Overview

Name   comZ   Type   Machinery gene
Locus tag   THTHE16_RS06285 Genome accession   NC_017272
Coordinates   1185711..1187426 (+) Length   571 a.a.
NCBI ID   WP_014510474.1    Uniprot ID   F6DHL7
Organism   Thermus thermophilus SG0.5JP17-16     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1180711..1192426
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  THTHE16_RS06260 (Ththe16_1228) - 1182308..1183288 (-) 981 WP_008631297.1 YpdA family putative bacillithiol disulfide reductase -
  THTHE16_RS06265 (Ththe16_1229) pilA/pilA1 1183446..1183916 (+) 471 WP_014510470.1 GspH/FimT family protein Machinery gene
  THTHE16_RS06270 (Ththe16_1230) - 1183972..1184445 (+) 474 WP_014510471.1 GspH/FimT family pseudopilin -
  THTHE16_RS06275 (Ththe16_1231) pilA/pilA2 1184442..1184999 (+) 558 WP_014510472.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  THTHE16_RS06280 (Ththe16_1232) pilA/pilA3 1184996..1185700 (+) 705 WP_014510473.1 PilW family protein Machinery gene
  THTHE16_RS06285 (Ththe16_1233) comZ 1185711..1187426 (+) 1716 WP_014510474.1 pilus assembly PilX N-terminal domain-containing protein Machinery gene
  THTHE16_RS12275 (Ththe16_1234) - 1187666..1188073 (+) 408 WP_014510475.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  THTHE16_RS06295 (Ththe16_1235) - 1188242..1188439 (+) 198 WP_018461701.1 nucleotidyltransferase family protein -
  THTHE16_RS06300 (Ththe16_1236) - 1188610..1189089 (+) 480 WP_014510476.1 DUF1640 domain-containing protein -
  THTHE16_RS06305 (Ththe16_1237) - 1189165..1189707 (+) 543 WP_008631313.1 Uma2 family endonuclease -
  THTHE16_RS06310 (Ththe16_1238) - 1189730..1190029 (+) 300 WP_008631315.1 nucleotidyltransferase family protein -
  THTHE16_RS06315 (Ththe16_1240) - 1190236..1190793 (-) 558 WP_014510477.1 Uma2 family endonuclease -
  THTHE16_RS06320 (Ththe16_1241) - 1190812..1191468 (-) 657 WP_014510478.1 chromosome segregation protein ScpA -

Sequence

Protein


Download         Length: 571 a.a.        Molecular weight: 61558.26 Da        Isoelectric Point: 7.4396

>NTDB_id=45781 THTHE16_RS06285 WP_014510474.1 1185711..1187426(+) (comZ) [Thermus thermophilus SG0.5JP17-16]
MNRKGIALVATLALMVVIALLVFGTFFTTQIELWTTRNDTTSVQAFYAAEAGLQKYKAALFQQYVWREQRGGTGGGGGCF
TSLARGLDLDRDGILTPFVNNRLVLAQNEVVTDANGNPVGRYTATLYKDAQDGQLFTLVSEGTSGGAKARVQATFRISNS
DYLEQAIFAGAGQANKWLNGRATIRGGVYVVGSPNNPDQYVIKTNGNFALYNWYDLTTYSGIADRVERSYQRVNDLCASL
RVQYGKISVGGSTQIGEPDNKVKGVFVGRGAQDITGNNEDVCQSNKGVCTEAMGPFDLSNPPPFPTLDAKLNSPACESYS
TWRSCLQDKAALHIQRIGNEVSVAKPLSVTLNSTCLSAMTTGTLTLDNTTVDCTFTQLDGTLGGFKYTYAGGQGLLELYG
DVVLEGLNLELKQATEYKALSGTKKSATLVVLKRNNQGGDVDINGNLLPQTSHGLFPNHVLGLVAEGDIYQQGQYVMAPL
YAGGTFRVVQDNVLFGSVIANEFCTTSAGGQNTGNQGGNKNNKNEEKEDQCNAGQKAEVVYIRIPKENRPALLPSLKGGK
PVFQILSYERR

Nucleotide


Download         Length: 1716 bp        

>NTDB_id=45781 THTHE16_RS06285 WP_014510474.1 1185711..1187426(+) (comZ) [Thermus thermophilus SG0.5JP17-16]
GTGAACCGCAAAGGTATCGCCCTCGTAGCCACTTTGGCCCTCATGGTGGTCATCGCCCTCTTGGTCTTCGGCACCTTCTT
CACCACCCAGATAGAGCTCTGGACCACCCGCAACGACACCACCTCGGTCCAGGCCTTCTACGCCGCCGAGGCGGGGTTAC
AGAAGTACAAGGCCGCCCTCTTCCAGCAGTACGTCTGGCGGGAGCAGCGGGGCGGGACGGGGGGAGGTGGGGGCTGCTTC
ACCTCCCTGGCAAGGGGGCTAGACCTGGACCGGGATGGAATCCTCACCCCCTTCGTCAACAACCGGCTGGTCCTGGCGCA
AAACGAGGTGGTCACCGACGCCAACGGAAACCCCGTGGGGCGGTACACGGCAACCCTTTACAAGGACGCCCAAGACGGCC
AGCTCTTCACCCTGGTGTCCGAGGGCACCTCGGGCGGGGCCAAGGCCCGGGTCCAGGCCACCTTCCGCATCAGCAACTCG
GACTACCTAGAGCAGGCCATCTTCGCCGGCGCGGGCCAGGCCAACAAGTGGCTGAACGGCAGGGCCACCATCCGGGGTGG
GGTCTACGTGGTGGGAAGCCCTAACAACCCGGACCAGTACGTCATAAAGACCAACGGCAACTTCGCCCTCTACAACTGGT
ATGACCTTACCACCTACTCCGGAATCGCCGACCGGGTGGAACGCAGCTACCAGCGGGTCAACGACCTCTGTGCAAGCCTT
AGGGTGCAGTACGGCAAAATTTCCGTGGGTGGCAGCACACAAATCGGCGAACCCGACAACAAGGTAAAGGGGGTTTTCGT
GGGCCGGGGAGCTCAGGACATCACCGGGAACAACGAGGACGTTTGCCAAAGCAACAAAGGCGTCTGCACCGAGGCCATGG
GTCCCTTTGACCTCTCCAACCCGCCCCCCTTCCCGACCCTGGACGCCAAGCTGAACTCCCCCGCCTGCGAGAGCTACAGC
ACCTGGCGGTCCTGCCTGCAGGACAAAGCCGCCTTGCACATCCAGCGTATCGGTAACGAGGTGAGCGTTGCCAAGCCCCT
TAGCGTCACCCTGAATTCCACCTGCCTGAGCGCCATGACCACGGGAACCCTCACCCTGGACAACACCACCGTGGACTGCA
CCTTCACCCAGTTGGACGGCACCCTGGGAGGCTTCAAGTACACCTACGCGGGCGGGCAGGGGCTTTTGGAACTCTACGGG
GACGTGGTCCTGGAGGGGCTAAACCTGGAGCTGAAGCAAGCCACAGAGTACAAGGCCCTCTCCGGCACCAAGAAGAGCGC
CACCCTCGTGGTGCTGAAGAGGAACAACCAAGGAGGCGACGTGGACATAAACGGCAATCTCCTCCCCCAAACCAGCCACG
GCCTTTTCCCCAACCATGTCCTGGGCCTGGTGGCGGAAGGCGACATCTACCAGCAGGGCCAGTACGTCATGGCCCCCCTC
TATGCGGGCGGGACCTTCCGGGTGGTGCAGGACAACGTGCTTTTCGGTTCTGTCATCGCCAACGAGTTTTGCACCACCAG
CGCTGGCGGCCAAAACACCGGTAATCAAGGCGGAAATAAAAATAATAAGAACGAGGAGAAGGAAGACCAATGCAACGCCG
GCCAGAAGGCCGAGGTGGTCTACATCCGCATCCCCAAGGAAAACCGCCCCGCCCTCCTACCAAGCCTCAAAGGCGGGAAA
CCCGTCTTCCAGATCCTCTCCTATGAACGGCGCTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F6DHL7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comZ Thermus thermophilus HB27

80.21

100

0.802

Multiple sequence alignment