Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   JJB22_RS13435 Genome accession   NZ_CP067307
Coordinates   2854528..2856360 (-) Length   610 a.a.
NCBI ID   WP_208782350.1    Uniprot ID   -
Organism   Escherichia coli strain ABW_A19     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2849528..2861360
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJB22_RS13385 (JJB22_13380) azuC 2849528..2849614 (-) 87 WP_010723106.1 stress response protein AzuC -
  JJB22_RS13390 (JJB22_13385) yecR 2849877..2850200 (+) 324 WP_001237869.1 YecR-like lipofamily protein -
  JJB22_RS13395 (JJB22_13390) ftnA 2850371..2850868 (+) 498 WP_000917208.1 non-heme ferritin -
  JJB22_RS13400 (JJB22_13395) yecH 2850906..2851145 (-) 240 WP_000377225.1 YecH family metal-binding protein -
  JJB22_RS13405 (JJB22_13400) tyrP 2851336..2852547 (+) 1212 WP_000797560.1 tyrosine transporter TyrP -
  JJB22_RS13410 (JJB22_13405) yecA 2852609..2853274 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  JJB22_RS13430 (JJB22_13425) pgsA 2853923..2854471 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JJB22_RS13435 (JJB22_13430) uvrC 2854528..2856360 (-) 1833 WP_208782350.1 excinuclease ABC subunit UvrC Machinery gene
  JJB22_RS13440 (JJB22_13435) letA 2856357..2857013 (-) 657 WP_208782352.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JJB22_RS27325 - 2857155..2857226 (+) 72 Protein_2668 transcriptional regulator -
  JJB22_RS13445 (JJB22_13440) yecU 2857309..2857485 (+) 177 WP_000590347.1 protein YecU -
  JJB22_RS13450 (JJB22_13445) yecF 2857472..2857696 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  JJB22_RS13455 (JJB22_13450) sdiA 2857763..2858485 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  JJB22_RS13460 (JJB22_13455) tcyN 2858715..2859467 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JJB22_RS13465 (JJB22_13460) tcyL 2859464..2860132 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  JJB22_RS13470 (JJB22_13465) dcyD 2860147..2861133 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68271.17 Da        Isoelectric Point: 9.4502

>NTDB_id=457796 JJB22_RS13435 WP_208782350.1 2854528..2856360(-) (uvrC) [Escherichia coli strain ABW_A19]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGIRPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIVKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=457796 JJB22_RS13435 WP_208782350.1 2854528..2856360(-) (uvrC) [Escherichia coli strain ABW_A19]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCATATCCTTTTATCTTCCT
GAGTGGCGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCAAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAACAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATATCAGATAGGACGTTGTCTGGGGCCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTGATTAGCCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAGTTTGTGTCCAATACCGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTTGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTGGAAACCTTCGTAGGACAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATAGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGTGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACAGGCATCAGGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TTGACGACAGTAAGATCCCTGATGTGATCCTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACATGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGCCGGCAAATGTTGTTGAAATATATGGGTGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGTAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

38.056

99.508

0.379
  uvrC Streptococcus pneumoniae R6

37.727

99.508

0.375
  uvrC Streptococcus pneumoniae D39

37.727

99.508

0.375