Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   JGU77_RS03740 Genome accession   NZ_CP066806
Coordinates   774510..775169 (-) Length   219 a.a.
NCBI ID   WP_033560344.1    Uniprot ID   -
Organism   Escherichia coli strain TCM3e1     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 769510..780169
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JGU77_RS03715 (JGU77_03715) - 770252..771199 (+) 948 WP_001296418.1 iron-siderophore ABC transporter substrate-binding protein -
  JGU77_RS03720 (JGU77_03720) - 771196..772083 (+) 888 WP_075862116.1 MurR/RpiR family transcriptional regulator -
  JGU77_RS03725 (JGU77_03725) ygiN 772128..772442 (-) 315 WP_000633738.1 putative quinol monooxygenase -
  JGU77_RS03730 (JGU77_03730) mdaB 772473..773054 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  JGU77_RS03735 (JGU77_03735) qseC 773164..774513 (-) 1350 WP_106106772.1 quorum sensing histidine kinase QseC -
  JGU77_RS03740 (JGU77_03740) ciaR 774510..775169 (-) 660 WP_033560344.1 quorum sensing response regulator transcription factor QseB Regulator
  JGU77_RS03745 (JGU77_03745) ygiW 775321..775713 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  JGU77_RS03750 (JGU77_03750) ygiV 775766..776248 (+) 483 WP_000183492.1 GyrI-like domain-containing protein -
  JGU77_RS03755 (JGU77_03755) ygiS 776357..777964 (+) 1608 WP_075862117.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24673.60 Da        Isoelectric Point: 6.9850

>NTDB_id=456415 JGU77_RS03740 WP_033560344.1 774510..775169(-) (ciaR) [Escherichia coli strain TCM3e1]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVVLDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=456415 JGU77_RS03740 WP_033560344.1 774510..775169(-) (ciaR) [Escherichia coli strain TCM3e1]
ATGCGAATTTTACTGATCGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGCGCACCTTATGATGCGGTGGTCCTGGATTTAACCT
TACCGGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTTTTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGCAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTTCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365