Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   JFL57_RS02330 Genome accession   NZ_CP066565
Coordinates   498785..500005 (+) Length   406 a.a.
NCBI ID   WP_012341581.1    Uniprot ID   A0A9Q7E4C6
Organism   Histophilus somni strain ASc-MMNZ-VFA-076     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 493785..505005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JFL57_RS02290 (JFL57_02290) - 493934..495070 (+) 1137 WP_075319828.1 RNA-guided endonuclease InsQ/TnpB family protein -
  JFL57_RS02295 (JFL57_02295) - 495294..495536 (+) 243 WP_011608610.1 hypothetical protein -
  JFL57_RS02300 (JFL57_02300) - 495575..496309 (+) 735 WP_075294059.1 4'-phosphopantetheinyl transferase family protein -
  JFL57_RS02310 (JFL57_02310) gltX 496648..498090 (-) 1443 WP_075294058.1 glutamate--tRNA ligase -
  JFL57_RS02330 (JFL57_02330) pilC 498785..500005 (+) 1221 WP_012341581.1 type II secretion system F family protein Machinery gene
  JFL57_RS02335 (JFL57_02335) pilD 500002..500709 (+) 708 WP_075294057.1 prepilin peptidase Machinery gene
  JFL57_RS02340 (JFL57_02340) coaE 500729..501376 (+) 648 WP_075294056.1 dephospho-CoA kinase -
  JFL57_RS02345 (JFL57_02345) yacG 501373..501567 (+) 195 WP_075294055.1 DNA gyrase inhibitor YacG -
  JFL57_RS02350 (JFL57_02350) - 501972..503348 (+) 1377 WP_075294054.1 alanine/glycine:cation symporter family protein -
  JFL57_RS02355 (JFL57_02355) raiA 503584..503901 (+) 318 WP_012341586.1 ribosome-associated translation inhibitor RaiA -
  JFL57_RS02360 (JFL57_02360) hpt 504105..504644 (+) 540 WP_011608620.1 hypoxanthine phosphoribosyltransferase -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46702.12 Da        Isoelectric Point: 9.7933

>NTDB_id=455560 JFL57_RS02330 WP_012341581.1 498785..500005(+) (pilC) [Histophilus somni strain ASc-MMNZ-VFA-076]
MQNLKLFSWKATNFLQQKQAGMLVIENVQEAKRYLLQQGLNNIYLQRHWQLNKKPKKIEFCDLLTQLAMLLQSSIPLKDS
LQILLRNCVNISLNQWVRYILKNLEGGLSFSQSVAQSGLYFSYQERQLISVGEMTGDLASVCQQIAEHRQQALALQRKIQ
KILLYPMIVLSISVILTALLLIFIVPQFAEMYGSNQSELPFFTQLLLNISSFLQQYFFHMIAVSILFFYLIKLRLHNSYS
FQLKKDWFLSHVPLLNKIIRLNRTISFCRSLGLMLNSGIPLQQSLYSFLPQNSINIQKKIEGDLTLINEVKLTLRGIEQG
YKFSQSVSSNLFSIQTQQMLQVGEKSGNLGLILQHIAENQQQQLDHQIDLLSQMLEPFMMVIIGGLIGLIMLGMYLPIFN
MGSLIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=455560 JFL57_RS02330 WP_012341581.1 498785..500005(+) (pilC) [Histophilus somni strain ASc-MMNZ-VFA-076]
ATGCAGAATTTGAAGCTATTTTCTTGGAAAGCCACTAATTTTTTACAGCAAAAACAAGCTGGAATGCTTGTTATCGAAAA
TGTACAAGAGGCCAAACGCTATTTATTACAACAAGGGCTAAACAATATATATTTACAGCGTCATTGGCAACTGAATAAAA
AGCCTAAAAAAATAGAATTTTGTGATCTATTAACTCAATTAGCAATGTTATTACAATCCTCAATTCCTTTAAAAGATAGC
TTACAAATTTTATTGAGAAATTGTGTTAATATTTCTTTAAATCAATGGGTTAGATATATTTTAAAAAATCTTGAAGGAGG
ATTATCTTTTTCACAATCTGTGGCTCAATCAGGTCTATATTTTTCTTATCAAGAACGCCAACTCATTTCTGTTGGAGAAA
TGACGGGAGATTTAGCCTCTGTTTGCCAACAAATAGCAGAACATCGTCAGCAGGCATTAGCATTACAACGCAAAATTCAA
AAAATTTTACTCTATCCAATGATAGTCTTAAGTATTTCTGTCATTCTCACCGCACTTCTATTAATTTTTATCGTGCCACA
ATTTGCCGAAATGTACGGTTCTAATCAATCCGAGCTTCCTTTTTTTACGCAGCTATTGTTAAACATATCCTCTTTTTTAC
AACAGTATTTTTTTCATATGATAGCGGTATCTATTTTATTTTTTTATCTAATAAAATTACGTTTACACAATTCATATAGT
TTTCAACTCAAAAAAGATTGGTTTTTATCGCATGTGCCGTTGTTAAATAAAATTATTCGGCTTAATAGAACGATAAGTTT
TTGCCGTAGTTTAGGATTAATGCTCAACTCAGGCATTCCTTTACAACAAAGTCTATATTCTTTCCTTCCCCAAAACTCTA
TCAACATACAGAAAAAGATTGAGGGAGATCTCACGTTAATTAATGAAGTAAAGCTAACATTACGTGGTATCGAACAAGGA
TATAAATTCTCTCAGTCTGTAAGCAGTAATTTGTTTTCTATACAAACACAACAAATGCTACAAGTTGGTGAAAAGAGTGG
AAATCTAGGTTTAATTCTGCAACATATCGCAGAAAATCAGCAACAACAGTTAGATCATCAAATTGATTTACTTTCACAAA
TGTTAGAACCGTTTATGATGGTGATCATTGGCGGATTAATAGGCTTGATTATGTTAGGTATGTATTTACCAATCTTTAAT
ATGGGAAGTTTAATTCAATGA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9Q7E4C6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

53.431

100

0.537
  pilC Haemophilus influenzae 86-028NP

53.102

99.261

0.527
  pilC Glaesserella parasuis strain SC1401

39.901

100

0.399